A weekly 4-methylpyrazole treatment attenuates the development of non-obese metabolic dysfunction-associated steatotic liver disease (MASLD) in male mice: Role of JNK.

Autor: Burger K; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Vienna, Austria., Jung F; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Vienna, Austria., Staltner R; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Vienna, Austria., Csarmann K; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Vienna, Austria., Schweiger K; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Vienna, Austria., Brandt A; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Vienna, Austria., Baumann A; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Vienna, Austria., Scholda J; Department of Pharmaceutical Sciences, Clinical Pharmacy Group, University of Vienna, Vienna, Austria., Kopp F; Department of Pharmaceutical Sciences, Clinical Pharmacy Group, University of Vienna, Vienna, Austria., Bergheim I; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Vienna, Austria.

Publikováno v: European journal of clinical investigation [Eur J Clin Invest] 2025 Jan; Vol. 55 (1), pp. e14320. Date of Electronic Publication: 2024 Sep 29.

When Vaping Isn't Actually Safer: A Death From Toxic Alcohol Contaminated Vape Juice.

Autor: Ogburn T; From the University of Nevada-Reno School of Medicine, Reno, NV., Chaudhry I; Washoe County Regional Medical Examiner's Office, and Department of Pathology, University of Nevada-Reno School of Medicine, Reno, NV., Knight LD; Washoe County Regional Medical Examiner's Office, and Departments of Pathology and Pediatrics, University of Nevada-Reno School of Medicine, Reno, NV.

Publikováno v: The American journal of forensic medicine and pathology [Am J Forensic Med Pathol] 2024 Dec 01; Vol. 45 (4), pp. 335-339. Date of Electronic Publication: 2024 May 23.

Transcriptome Study of Bursaphelenchus xylophilus Treated with Fomepizole Reveals a Serine/Threonine-Protein Phosphatase Gene that Is Substantially Linked with Vitality and Pathogenicity.

Autor: Wang L; College of Life Sciences, Qingdao University, Qingdao 266071, P.R. China., Qin C; College of Life Sciences, Qingdao University, Qingdao 266071, P.R. China., Guo Q; College of Life Sciences, Qingdao University, Qingdao 266071, P.R. China., Han Y; College of Life Sciences, Qingdao University, Qingdao 266071, P.R. China., Du G; College of Life Sciences, Qingdao University, Qingdao 266071, P.R. China., Li R; College of Life Sciences, Qingdao University, Qingdao 266071, P.R. China.

Publikováno v: Phytopathology [Phytopathology] 2024 Mar; Vol. 114 (3), pp. 630-640. Date of Electronic Publication: 2024 Mar 08.

Real-time visualization the pH fluctuations of living cells with a ratiometric near-infrared fluorescent probe.

Autor: Ma J; Department of Chemistry, Changzhi University, Changzhi 046011, PR China; Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China., Lu X; Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China., Hao M; Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China; University of Chinese Academy of Sciences, 100049 Beijing, PR China., Wang Y; Department of Chemistry, Changzhi University, Changzhi 046011, PR China., Guo Y; Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China. Electronic address: guoyong@licp.cas.cn., Wang Z; Department of Chemistry, Changzhi University, Changzhi 046011, PR China. Electronic address: czxywzj@163.com.

Publikováno v: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2024 Feb 05; Vol. 306, pp. 123572. Date of Electronic Publication: 2023 Oct 25.

High-Dose Acetaminophen with Concurrent CYP2E1 Inhibition Has Profound Anticancer Activity without Liver Toxicity.

Autor: Bryan A; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., Pingali P; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., Faber A; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., Landry J; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., Akakpo JY; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., Jaeschke H; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., Li H; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., Lee WS; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., May L; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., Patel B; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.)., Neuwelt A; Department of Veterans Affairs, Richmond, Virginia. (A.B., P.P., W.S.L., B.P., A.N.); Departments of Oral and Craniofacial Molecular Biology (A.F.) and Human and Molecular Genetics (J.L., L.M.), Virginia Commonwealth University, Richmond, Virginia; Department of Veterans Affairs, Charleston, South Carolina (H.L.); and Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas, Lawrence, Kansas (J.Y.A., H.J.) alexander.neuwelt@va.gov.

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2024 Jan 02; Vol. 388 (1), pp. 209-217. Date of Electronic Publication: 2024 Jan 02.