Zobrazeno 1 - 10
of 84
pro vyhledávání: '"FMNL1"'
Autor:
Ashton L. Sigler, Scott B. Thompson, Logan Ellwood-Digel, Adithan Kandasamy, Mary J. Michaels, Dean Thumkeo, Shuh Narumiya, Juan C. Del Alamo, Jordan Jacobelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Lymphocyte trafficking and migration through tissues is critical for adaptive immune function and, to perform their roles, T cells must be able to navigate through diverse tissue environments that present a range of mechanical challenges. T cells pre
Externí odkaz:
https://doaj.org/article/8d8a242143d24c529f8431db63d56272
Autor:
Xiaoxiao Wang, Zilong Wang, Baiyi Liu, Rui Jin, Yuyun Song, Ran Fei, Xu Cong, Rui Huang, Xiaohe Li, Jia Yang, Lai Wei, Huiying Rao, Feng Liu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe monocyte-macrophage-dendritic cell (DC) (MMD) system exerts crucial functions that may modulate fibrogenesis in nonalcoholic steatohepatitis (NASH). In this study, we explored the cell characteristics, distribution and developmental tra
Externí odkaz:
https://doaj.org/article/3f3b2584cc894984aac19b47b22c8625
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Formin-like (FMNL) proteins are responsible for cytoskeletal remodeling and have been implicated in the progression and spread of human cancers. Yet the clinical significance and biological function of FMNL1 in clear cell renal cell carcinoma (ccRCC)
Externí odkaz:
https://doaj.org/article/dfe2b93eeb72464b84638d30f0329cff
Autor:
Scott B Thompson, Adam M Sandor, Victor Lui, Jeffrey W Chung, Monique M Waldman, Robert A Long, Miriam L Estin, Jennifer L Matsuda, Rachel S Friedman, Jordan Jacobelli
Publikováno v:
eLife, Vol 9 (2020)
Lymphocyte migration is essential for the function of the adaptive immune system, and regulation of T cell entry into tissues is an effective therapy in autoimmune diseases. Little is known about the specific role of cytoskeletal effectors that media
Externí odkaz:
https://doaj.org/article/05848d0787a543cab416fc0649eb8077
Autor:
Ana Bello-Gamboa, Marta Velasco, Solange Moreno, Gonzalo Herranz, Roxana Ilie, Silvia Huetos, Sergio Dávila, Alicia Sánchez, Jorge Bernardino De La Serna, Víctor Calvo, Manuel Izquierdo
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
T-cell receptor stimulation induces the convergence of multivesicular bodies towards the microtubule-organizing centre (MTOC) and the polarization of the MTOC to the immune synapse (IS). These events lead to exosome secretion at the IS. We describe h
Externí odkaz:
https://doaj.org/article/a25386762720464da87db4b4874789f9
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 117, Iss , Pp - (2019)
Approximately 40% of patients with non-small cell lung cancer (NSCLC) develop bone metastasis. The formin protein formin-like 1 (FMNL1) plays a key role in the pathogenic processes of hematopoietic malignancies, and has been reported to be associated
Externí odkaz:
https://doaj.org/article/5eb610e96e344dd392ba9c42bb257fc9
Akademický článek
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Autor:
Zirui Wang, Lili Zhang, Panfeng Shang, Junyao Liu, Shengjun Fu, Duo Zheng, Gui Ma, Zhongjin Yue
Publikováno v:
Journal of Cancer
Purpose: In this study, we have undertaken the whole proteomic analysis and got a better understanding of biological processes involved in the development and progression of ccRCC. We hope promising biomarkers can be uncovered to facilitate early dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd84bbb7d18b363353ae3b9093f96281
https://doi.org/10.7150/jca.62309
https://doi.org/10.7150/jca.62309