Zobrazeno 1 - 10
of 98
pro vyhledávání: '"FLUORINATED NUCLEOSIDES"'
Akademický článek
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Autor:
Kler Huonnic, Bruno Linclau
Publikováno v:
CHEMICAL REVIEWS
Fluorinated carbohydrates have found many applications in the glycosciences. Typically, these contain fluorination at a single position. There are not many applications involving polyfluorinated carbohydrates, here defined as monosaccharides in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5174b3e01206289db545616838af8a00
https://pubmed.ncbi.nlm.nih.gov/35613331
https://pubmed.ncbi.nlm.nih.gov/35613331
Autor:
Luciano Mayol, Vincenzo Piccialli, Daniele D'Alonzo, Jussara Amato, Nicola Borbone, Giorgia Oliviero, Stefano D'Errico, Gennaro Piccialli
Publikováno v:
Molecules, Vol 17, Iss 11, Pp 13036-13044 (2012)
The substitution of a hydroxyl group by a fluorine atom in a potential drug is an efficient reaction that can, in principle, improve its pharmacological properties. Herein, the synthesis of the novel compound 5′-fluoro-5′-deoxyacadesine (5′-F-A
Externí odkaz:
https://doaj.org/article/353d6913fbf94f87b8a2453f3052974b
Akademický článek
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Autor:
Smolka, Ondřej
This thesis deals with the synthesis of prodrugs based on analogs of nucleoside phosphonates derived from 6-fluoro-3-hydroxypyrazine-2-carboxamide (T-705) and 3- hydroxypyrazine-2-carboxamide (T-1105). T-705 and T-1105 act as inhibitors of an influen
Externí odkaz:
http://www.nusl.cz/ntk/nusl-435858
Autor:
Nguyen, Van Hai
The key intermediate 6-amino-7-iodo-7-deazapurine 3'-deoxy-3'-fluororibonucleoside was synthesized using multistep sequence of several reactions, which started from the commercially available D-xylose and 6-chloro-7-deazapurine. The synthetic strateg
Externí odkaz:
http://www.nusl.cz/ntk/nusl-415871
Autor:
Smolka, Ondřej
This thesis deals with the synthesis of prodrugs based on analogs of nucleoside phosphonates derived from 6-fluoro-3-hydroxypyrazine-2-carboxamide (T-705) and 3- hydroxypyrazine-2-carboxamide (T-1105). T-705 and T-1105 act as inhibitors of an influen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::7e3acfa9fc972b377bf7a2d4f0462e76
http://www.nusl.cz/ntk/nusl-435858
http://www.nusl.cz/ntk/nusl-435858
Autor:
Štefek, Milan
This master thesis is dedicated to the preparation of fluorinated derivatives of carbocyclic nucleosides, that may serve as flaviviral replication inhibitors. Preparation of both monofluorinated as well as gem-difluorinated analogs of ribo and 2'-deo
Externí odkaz:
http://www.nusl.cz/ntk/nusl-406273
Autor:
Štefek, Milan
This master thesis is dedicated to the preparation of fluorinated derivatives of carbocyclic nucleosides, that may serve as flaviviral replication inhibitors. Preparation of both monofluorinated as well as gem-difluorinated analogs of ribo and 2'-deo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::e8d110ea2b5949c25d87dc900a314262
http://www.nusl.cz/ntk/nusl-406273
http://www.nusl.cz/ntk/nusl-406273
Autor:
Armando Zarrelli, Giovanni Di Fabio, Giovanni Palumbo, Annalisa Guaragna, Daniele D'Alonzo, Maria De Fenza, Valeria Romanucci
Publikováno v:
Synthesis. 49:998-1008
The synthesis of (1'S,2'S,4'R) and (1'S,2'R,4'R) stereoisomers of 2'-fluoro-3'-thiacytidine [(2' S)-F-3TC and (2' R)-F-3TC], the earliest examples of oxathiolanyl nucleosides with a fluorine atom in the 'sugar' backbone, is herein reported. From of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9de2f889067fd95ec7d75d6424021f0
https://doi.org/10.1055/s-0036-1588680
https://doi.org/10.1055/s-0036-1588680