Zobrazeno 1 - 10
of 7 375
pro vyhledávání: '"FLT3"'
Autor:
Ling Jiang, Yu Zhao, Fang Liu, Yun Huang, Yujiao Zhang, Baoyi Yuan, Jiaying Cheng, Ping Yan, Jinle Ni, Yongshuai Jiang, Quan Wu, Xuejie Jiang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Approximately 25–30% of patients with acute myeloid leukemia (AML) have FMS-like receptor tyrosine kinase-3 (FLT3) mutations that contribute to disease progression and poor prognosis. Prolonged exposure to FLT3 tyrosine kinase i
Externí odkaz:
https://doaj.org/article/14b61ae9140e425ebfee0407ee01a1be
Autor:
Chuhong Hu, Yvyin Zhang, Jie Yang, Yanli Xu, Tingfen Deng, Yumiao Li, Shilin Xu, Shunqing Wang, Peihong Wang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is a common mutation type in acute myeloid leukemia (AML) and is usually associated with poor patient prognosis. With advancements in molecular diagnostics and the
Externí odkaz:
https://doaj.org/article/8009670eecd249c4ad38edcc32956240
Autor:
Liu Jianwei, Gu Jianguo
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1199-1207 (2024)
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase expressed in hematopoietic cells. Internal-tandem duplication domain (ITD) mutation and tyrosine kinase domain (TKD) mutation are the two most common mutations in acute myeloid leukemia
Externí odkaz:
https://doaj.org/article/a040752fc06f4781813d074953acfa5a
Autor:
Meng Zhang, Mei-Ling She, Jun Chen, Xiao-Qi Zeng, Qing-Quan Xiong, Ying-Huan Cen, Jia-An Ye, Guo-Bin Qiu, Shu-Yi Yang, Guang-Hui Ren
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117603- (2024)
Multi-drug resistance (MDR) poses a significant challenge to cancer treatment. Targeting ATP-binding cassette subfamily B member 1 (ABCB1) is a viable strategy for overcoming MDR. This study examined the preclinical in vitro and animal studies that u
Externí odkaz:
https://doaj.org/article/273f1352baaf47069f41b66f52ec6cd9
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Transient Perivascular Inflammation of the\ Carotid Artery (TIPIC) syndrome is uncommon, and cases of TIPIC induced by the targeted drug, sorafenib, are extremely rare. This case report describes a patient with acute myeloid leukemia carrying an FMS
Externí odkaz:
https://doaj.org/article/8c8acb52e97e4373b3f5ff764cd39a0c
Publikováno v:
Brazilian Journal of Biology, Vol 84 (2024)
Abstract This study aimed to investigate the impact of Vernonia amygdalina leaf extract on FLT3 regulation. V. amygdalina was extracted with 96% ethanol (VAE-96), and its cytotoxicity against FLT3- cell lines (MOLM-13 and MV-4-11) was evaluated. The
Externí odkaz:
https://doaj.org/article/1a3cef1efc8e46868fc111f476b0700f
Autor:
Karam Ashouri, Krithika Chennapan, Anastasia Martynova, Samvel Nazaretyan, Amir Ali, Anush Aram Ginosyan, Eric Tam, Abdullah Ladha, Karrune Woan, Preet Chaudhary, Imran Siddiqi, George Yaghmour
Publikováno v:
eJHaem, Vol 5, Iss 2, Pp 423-427 (2024)
Externí odkaz:
https://doaj.org/article/275e3b98e2f440e8abd653b714c3971f
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
ABSTRACTObjective: Extramedullary relapse (EMR) is rare in acute promyelocytic leukemia (APL) and, there is a lack of information on its management. Current practices for EMR in APL are always to adopt strategies from other subtypes of Acute lymphobl
Externí odkaz:
https://doaj.org/article/fc78f18c7ef54d06b5baf47e66b46a1d
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Akademický článek
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