Zobrazeno 1 - 10
of 197
pro vyhledávání: '"FLORENZ SASSE"'
Autor:
Saheed O. Anifowose, Wejdan S. N. Alqahtani, Badr A. Al-Dahmash, Florenz Sasse, Maroua Jalouli, Mourad A. M. Aboul-Soud, Ahmed Y. Badjah-Hadj-Ahmed, Yasser A. Elnakady
Publikováno v:
Molecules, Vol 27, Iss 23, p 8307 (2022)
Bioprospecting natural products to find prominent agents for medical application is an area of scientific endeavor that has produced many clinically used bioactive compounds, including anticancer agents. These compounds come from plants, microorganis
Externí odkaz:
https://doaj.org/article/4b1c2083a26a49eb976988f4b213218b
Autor:
Yazh Muthukumar, Johanna Münkemer, Daniel Mathieu, Christian Richter, Harald Schwalbe, Heinrich Steinmetz, Wolfgang Kessler, Joachim Reichelt, Ulrike Beutling, Ronald Frank, Konrad Büssow, Joop van den Heuvel, Mark Brönstrup, Richard E Taylor, Sabine Laschat, Florenz Sasse
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201605 (2018)
The identification of inhibitors of eukaryotic protein biosynthesis, which are targeting single translation factors, is highly demanded. Here we report on a small molecule inhibitor, gephyronic acid, isolated from the myxobacterium Archangium gephyra
Externí odkaz:
https://doaj.org/article/773d2a0fde3942c3a38ead1de53be427
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 535-543 (2014)
The preparation of alkyne-modified ansamitocins by mutasynthetic supplementation of Actinosynnema pretiosum mutants with alkyne-substituted aminobenzoic acids is described. This modification paved the way to introduce a thiol linker by Huisgen-type c
Externí odkaz:
https://doaj.org/article/8d6498ead2da499897a399bf28f3115a
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 861-869 (2012)
We describe the unprecedented formation of six ansamitocin derivatives that are deoxygenated at C-7 of the ansamitocin core, obtained during fermentation experiments by employing a variety of Actinosynnema pretiosum mutants and mutasynthetic approach
Externí odkaz:
https://doaj.org/article/6b39916c9ab44e218d6b12e0924608eb
Autor:
Irene Wagner-Dobler, Randi Diestel, Florenz Sasse, Jeroen S. Dickschat, Brigitte Kunze, Stefan Schulz
Publikováno v:
Marine Drugs, Vol 8, Iss 12, Pp 2976-2987 (2010)
The antiproliferative activity of 52 volatile compounds released from bacteria was investigated in agar diffusion assays against medically important microorganisms and mouse fibroblasts. Furthermore, the activity of these compounds to interfere with
Externí odkaz:
https://doaj.org/article/f79510a1fca94ae59c9419686146cae4
Autor:
Mark Brönstrup, Frank Klawonn, Bettina Hinkelmann, Raimo Franke, Theresia E. B. Stradal, Florenz Sasse, Verena Fetz
Publikováno v:
SLAS DISCOVERY: Advancing Life Sciences R&D
Mode of action (MoA) identification of bioactive compounds is very often a challenging and time-consuming task. We used a label-free kinetic profiling method based on an impedance readout to monitor the time-dependent cellular response profiles for t
Autor:
Florenz Sasse, Mark Brönstrup
Publikováno v:
Natural product reports
England
England
Covering: 2000 to 2020 The translation of mRNA into proteins is a precisely regulated, complex process that can be divided into three main stages, i.e. initiation, elongation, termination, and recycling. This contribution is intended to highlight how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a47c0f7b5440517ddbd684077be039
https://hdl.handle.net/10033/622887
https://hdl.handle.net/10033/622887
Publikováno v:
Kavaka. 57:1
Autor:
Florenz Sasse, Maira Peres de Carvalho, Matheus Weiler Amaral, Heinrich Lünsdorf, Giuseppe Gulotta, Wolf-Rainer Abraham
Publikováno v:
Environmental Microbiology. 18:4254-4264
Pathogens embedded in biofilms are involved in many infections and are very difficult to treat with antibiotics because of higher resistance compared to planktonic cells. Therefore, new approaches for their control are urgently needed. One way to sea
Autor:
Carsten Zeilinger, Lena Mancuso, Andreas Kirschning, Benjamin Schröder, Simone Eichner, Florenz Sasse, Jekaterina Hermane
Publikováno v:
Organic and Biomolecular Chemistry 17 (2019), Nr. 21
Organic & biomolecular chemistry
Organic & Biomolecular Chemistry 17 (2019), Nr. 21
Organic & biomolecular chemistry
Organic & Biomolecular Chemistry 17 (2019), Nr. 21
Mutasynthetic supplementation of the AHBA blocked mutant strain of S. hygroscopicus, the geldanamycin producer, with 21 aromatic and heteroaromatic amino acids provided new nonquinoid geldanamycin derivatives. Large scale (5 L) fermentation provided
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe2d7042f7935365b7df7b6c16eb9c2