Zobrazeno 1 - 9
of 9
pro vyhledávání: '"FLD, fatty liver disease"'
Autor:
Fei Luo, Eriks Smagris, Sarah A. Martin, Goncalo Vale, Jeffrey G. McDonald, Justin A. Fletcher, Shawn C. Burgess, Helen H. Hobbs, Jonathan C. Cohen
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 879-899 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 879-899 (2022)
Background & Aims: Substitution of lysine for glutamic acid at residu 167 in Transmembrane 6 superfamily member 2 (TM6SF2) is associated with fatty liver disease and reduced plasma lipid levels. Tm6sf2-/- mice replicate the human phenotype but were n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c501eab0983bab28ced1482110d3291c
http://europepmc.org/articles/PMC8804273
http://europepmc.org/articles/PMC8804273
Autor:
Harry L.A. Janssen, Laurens A. van Kleef, Bettina E. Hansen, Keyur Patel, Willem P. Brouwer, Robert A. de Man, Hannah S.J. Choi, Robert J. de Knegt, Milan J. Sonneveld
Publikováno v:
JHEP Reports, Vol 3, Iss 5, Pp 100350-(2021)
JHEP Reports
JHEP Reports, 3(5):100350. Elsevier
JHEP Reports
JHEP Reports, 3(5):100350. Elsevier
Background & Aims A recent consensus document has defined metabolic dysfunction-associated fatty liver disease (MAFLD) as hepatic steatosis together with overweight, diabetes, and/or a combination of other metabolic risk factors. The clinical relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea513ed394452d7f95cca663d85f99f
http://www.sciencedirect.com/science/article/pii/S2589555921001269
http://www.sciencedirect.com/science/article/pii/S2589555921001269
Autor:
Oveis Jamialahmadi, Antonio Picardi, Luca Valenti, Roberta Pujia, Federica Tavaglione, Umberto Vespasiani-Gentilucci, Stefano Romeo, Antonio De Vincentis, Rocco Spagnuolo, Susanna Morano
Publikováno v:
JHEP Reports, Vol 3, Iss 3, Pp 100262-(2021)
JHEP Reports
JHEP Reports
Background & Aims Type 2 diabetes is a major driver of fatty liver disease and its long-term complications. The aim of this study was to investigate the individual contribution of inborn and acquired risk factors for severe liver disease in individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3548cf2562154577ca36519f424df8d4
https://pubmed.ncbi.nlm.nih.gov/33997749
https://pubmed.ncbi.nlm.nih.gov/33997749
Autor:
Hartmut Ruetten, Sebastian Brachs, Dieter Schmoll, Bodo Brunner, Joachim Spranger, Angelika F. Winkel, Kerstin Jahn-Hofmann, Andreas L. Birkenfeld, Hui Tang, Daniel Margerie
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 5, Iss 11, Pp 1072-1082 (2016)
Molecular Metabolism, Vol 5, Iss 11, Pp 1072-1082 (2016)
Objective Non-alcoholic fatty liver disease is a world-wide health concern and risk factor for cardio-metabolic diseases. Citrate uptake modifies intracellular hepatic energy metabolism and is controlled by the conserved sodium-dicarboxylate cotransp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387a0397cf560df92007d51d7e2ffd73
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100284-(2021)
JHEP Reports, Vol 3, Iss 3, Pp 100284-(2021)
Summary: Fatty liver disease can be triggered by a combination of excess alcohol, dysmetabolism and other environmental cues, which can lead to steatohepatitis and can evolve to acute/chronic liver failure and hepatocellular carcinoma, especially in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208fb7d0b5b574d80e6e97a913828e36
Autor:
van Kleef LA; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands., Choi HSJ; Toronto Centre for Liver Disease, University Health Network, Toronto, Canada., Brouwer WP; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands., Hansen BE; Toronto Centre for Liver Disease, University Health Network, Toronto, Canada., Patel K; Toronto Centre for Liver Disease, University Health Network, Toronto, Canada., de Man RA; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands., Janssen HLA; Toronto Centre for Liver Disease, University Health Network, Toronto, Canada., de Knegt RJ; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands., Sonneveld MJ; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2021 Aug 08; Vol. 3 (5), pp. 100350. Date of Electronic Publication: 2021 Aug 08 (Print Publication: 2021).
Genetic predisposition similarities between NASH and ASH: Identification of new therapeutic targets.
Autor:
Bianco C; Precision Medicine - Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Casirati E; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Malvestiti F; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Valenti L; Precision Medicine - Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2021 Mar 30; Vol. 3 (3), pp. 100284. Date of Electronic Publication: 2021 Mar 30 (Print Publication: 2021).
Autor:
Tavaglione F; Clinical Medicine and Hepatology Unit, Department of Internal Medicine and Geriatrics, Campus Bio-Medico University, Rome, Italy.; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden., De Vincentis A; Internal Medicine Unit, Department of Internal Medicine and Geriatrics, Campus Bio-Medico University, Rome, Italy.; Clinical Lecturer of Internal Medicine, Saint Camillus International University of Health and Medical Sciences, Rome, Italy., Jamialahmadi O; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden., Pujia R; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, University Magna Graecia, Catanzaro, Italy., Spagnuolo R; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, University Magna Graecia, Catanzaro, Italy., Picardi A; Clinical Medicine and Hepatology Unit, Department of Internal Medicine and Geriatrics, Campus Bio-Medico University, Rome, Italy., Morano S; Department of Experimental Medicine, Sapienza University, Rome, Italy., Valenti L; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.; Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Romeo S; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden.; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, University Magna Graecia, Catanzaro, Italy.; Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden., Vespasiani-Gentilucci U; Clinical Medicine and Hepatology Unit, Department of Internal Medicine and Geriatrics, Campus Bio-Medico University, Rome, Italy.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2021 Mar 02; Vol. 3 (3), pp. 100262. Date of Electronic Publication: 2021 Mar 02 (Print Publication: 2021).
Autor:
Brachs S; Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité - University School of Medicine, Berlin, 10117, Germany; DZHK (German Center for Cardiovascular Research), Partner Site, Berlin, Germany. Electronic address: Sebastian.Brachs@charite.de., Winkel AF; Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, 65926, Germany. Electronic address: Angelika.Winkel@sanofi.com., Tang H; Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité - University School of Medicine, Berlin, 10117, Germany; DZHK (German Center for Cardiovascular Research), Partner Site, Berlin, Germany. Electronic address: Hui.Tang@charite.de., Birkenfeld AL; Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité - University School of Medicine, Berlin, 10117, Germany; DZHK (German Center for Cardiovascular Research), Partner Site, Berlin, Germany; Section of Metabolic Vascular Medicine, Medical Clinic III and Paul Langerhans Institute Dresden (PLID), a Member of the German Diabetes Center (DZD), Technische Universität, Dresden, 01307, Germany. Electronic address: Andreas.Birkenfeld@uniklinikum-dresden.de., Brunner B; Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, 65926, Germany. Electronic address: Bodo.Brunner@sanofi.com., Jahn-Hofmann K; Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, 65926, Germany. Electronic address: Kerstin.Jahn-Hofmann@sanofi.com., Margerie D; Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, 65926, Germany. Electronic address: Daniel.Margerie@sanofi.com., Ruetten H; Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, 65926, Germany. Electronic address: Hartmut.Ruetten@sanofi.com., Schmoll D; Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, 65926, Germany. Electronic address: Dieter.Schmoll@sanofi.com., Spranger J; Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité - University School of Medicine, Berlin, 10117, Germany; DZHK (German Center for Cardiovascular Research), Partner Site, Berlin, Germany. Electronic address: joachim.spranger@charite.de.
Publikováno v:
Molecular metabolism [Mol Metab] 2016 Aug 13; Vol. 5 (11), pp. 1072-1082. Date of Electronic Publication: 2016 Aug 13 (Print Publication: 2016).