Zobrazeno 1 - 10
of 409
pro vyhledávání: '"FLASH radiotherapy"'
Publikováno v:
Journal of Synchrotron Radiation, Vol 31, Iss 5, Pp 1189-1196 (2024)
The Circular Electron–Positron Collider (CEPC) in China can also work as an excellent powerful synchrotron light source, which can generate high-quality synchrotron radiation. This synchrotron radiation has potential advantages in the medical field
Externí odkaz:
https://doaj.org/article/ae755a68caa74242865e32dd5f0dd3ee
Autor:
Hanchen Shen, Hongbin Wang, Jianlan Mo, Jianyu Zhang, Changhuo Xu, Feiyi Sun, Xinwen Ou, Xinyan Zhu, Lidong Du, Huaqiang Ju, Ruquan Ye, Guangfu Shi, Ryan T.K. Kwok, Jacky W.Y. Lam, Jianwei Sun, Tianfu Zhang, Shipeng Ning, Ben Zhong Tang
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 299-312 (2024)
Ultrahigh dose-rate (FLASH) radiotherapy is an emerging technology with excellent therapeutic effects and low biological toxicity. However, tumor recurrence largely impede the effectiveness of FLASH therapy. Overcoming tumor recurrence is crucial for
Externí odkaz:
https://doaj.org/article/f3b895ccb8d1429386dc260ec747833c
Autor:
Hannah C. Wanstall, Pierre Korysko, Wilfred Farabolini, Roberto Corsini, Joseph J. Bateman, Vilde Rieker, Abigail Hemming, Nicholas T. Henthorn, Michael J. Merchant, Elham Santina, Amy L. Chadwick, Cameron Robertson, Alexander Malyzhenkov, Roger M. Jones
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Ultra-high dose rate (UHDR) irradiation has been shown to have a sparing effect on healthy tissue, an effect known as ‘FLASH’. This effect has been studied across several radiation modalities, including photons, protons and clinical ener
Externí odkaz:
https://doaj.org/article/61a9decb02b44d5288fc685095853dbb
Autor:
EC Daugherty, Y Zhang, Z Xiao, AE Mascia, M Sertorio, J Woo, C McCann, KJ Russell, RA Sharma, D Khuntia, JD Bradley, CB Simone, JC Breneman, JP Perentesis
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background FLASH therapy is a treatment technique in which radiation is delivered at ultra-high dose rates (≥ 40 Gy/s). The first-in-human FAST-01 clinical trial demonstrated the clinical feasibility of proton FLASH in the treatment of ext
Externí odkaz:
https://doaj.org/article/3730163268f8475da81223dd3a8d96e9
Autor:
Fabio Di Martino, Emanuele Scifoni, Vincenzo Patera, Pierre Montay-Gruel, Francesco Romano, Arash Darafsheh, Valentina Tozzini
Publikováno v:
Frontiers in Physics, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/de94f9d30a974c06988a38b10805f24a
Autor:
Verdi Vanreusel, Hugo Vallet, Jordi Wijnen, Benjamin Côté, Paul Leblans, Paul Sterckx, Dirk Vandenbroucke, Dirk Verellen, Luana de Freitas Nascimento
Publikováno v:
Photonics, Vol 11, Iss 9, p 865 (2024)
Dosimetry is crucial in radiotherapy to warrant safe and correct treatment. In FLASH radiotherapy, where ultra-high dose rates (UHDRs) are used, the dosimetric demands are more stringent, requiring the development and investigation of new dosemeters.
Externí odkaz:
https://doaj.org/article/d8a86764c7f44205994fe1540168bbd0
Autor:
Umberto Deut, Aurora Camperi, Cristiano Cavicchi, Roberto Cirio, Emanuele Maria Data, Elisabetta Alessandra Durisi, Veronica Ferrero, Arianna Ferro, Simona Giordanengo, Oscar Martì Villarreal, Felix Mas Milian, Elisabetta Medina, Diango M. Montalvan Olivares, Franco Mostardi, Valeria Monti, Roberto Sacchi, Edoardo Salmeri, Anna Vignati
Publikováno v:
Applied Sciences, Vol 14, Iss 17, p 7582 (2024)
Irradiations at Ultra-High Dose Rate (UHDR) regimes, exceeding 40 Gy/s in single fractions lasting less than 200 ms, have shown an equivalent antitumor effect compared to conventional radiotherapy with reduced harm to normal tissues. This work detail
Externí odkaz:
https://doaj.org/article/2267e99d252a4588b8674d38f2940227
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionFLASH proton therapy (FLASH-PT) requires ultra-high dose rate (≥ 40 Gy/s) protons to be delivered in a short timescale whilst conforming to a patient-specific target. This study investigates the feasibility and constraints of Bragg peak
Externí odkaz:
https://doaj.org/article/c8977bed619041f492f20fd50a865809
Autor:
Rémy Kinj, Olivier Gaide, Wendy Jeanneret-Sozzi, Urania Dafni, Stéphanie Viguet-Carrin, Enea Sagittario, Magdalini Kypriotou, Julie Chenal, Frederic Duclos, Marine Hebeisen, Teresa Falco, Reiner Geyer, Patrik Gonçalves Jorge, Raphaël Moeckli, Jean Bourhis
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 45, Iss , Pp 100743- (2024)
Background: Cutaneous basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most prevalent skin cancers in western countries. Surgery is the standard of care for these cancers and conventional external radiotherapy (CONV-RT) with conve
Externí odkaz:
https://doaj.org/article/54ad39c994b04bd891c8f8a64eb87764
Autor:
Elisabetta Medina, Arianna Ferro, Mohammad Abujami, Aurora Camperi, Matteo Centis Vignali, Emanuele Data, Damiano Del Sarto, Umberto Deut, Fabio Di Martino, Mohammad Fadavi Mazinani, Marco Ferrero, Veronica Ferrero, Simona Giordanengo, Oscar A. Martì Villarreal, Mohammad Amin Hosseini, Felix Mas Milian, Luigi Masturzo, Diango M. Montalvan Olivares, Marco Montefiori, Giovanni Paternoster, Jake Harold Pensavalle, Valentina Sola, Roberto Cirio, Roberto Sacchi, Anna Vignati
Publikováno v:
Frontiers in Physics, Vol 12 (2024)
Monitoring Ultra-High Dose Rate (UHDR) beams is one of the multiple challenges posed by the emergent FLASH radiotherapy. Technologies (i.e., gas-filled ionization chambers) nowadays used in conventional radiotherapy are no longer effective when appli
Externí odkaz:
https://doaj.org/article/3b2a0e3546e7426194e3cce1aac0b2e9