Zobrazeno 1 - 10
of 2 221
pro vyhledávání: '"FKBP5"'
Autor:
Zhenjie Chen, Shi Fu, Yiqian Shan, Zexi He, Jun Gu, Haichao Wu, Jiawei Lin, Yinglong Huang, Haifeng Wang, Yangbai Lu, Mingxia Ding
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Prostate cancer (PCa), with high heterogeneity and poor prognosis, is one of the most common malignant tumors in men. Circular RNAs (circRNAs) have been identified in tumor progression and resistance to medication in numerous studies. Howeve
Externí odkaz:
https://doaj.org/article/9893fe391c8e4cc2b2159f0390e93b77
Autor:
Mengdi Chen, Congcong Zhang, Zewen Wu, Siwei Guo, Wenfa Lv, Jixuan Song, Beibei Hao, Jinhui Bai, Xinxin Zhang, Hongyan Xu, Guangjun Xia
Publikováno v:
Animal Bioscience, Vol 37, Iss 7, Pp 1156-1167 (2024)
Objective MicroRNAs (miRNAs) are endogenous non-coding RNAs that can play a role in the post-transcriptional regulation of mammalian preadipocyte differentiation. However, the precise functional mechanism of its regulation of fat metabolism is not fu
Externí odkaz:
https://doaj.org/article/56c9ddb6904649da8ca5d1b84a0f4085
Autor:
Arsenii Ya. Gayduk, Aleksei S. Sustretov, Daniil A. Kokorev, Aleksei A. Kuznetsov, Xenia Gonda, Alexander T. Sack, Timur S. Syunyakov, Darya A. Smirnova
Publikováno v:
Наука и инновации в медицине, Vol 9, Iss 1, Pp 61-67 (2024)
The increasing relevance of PTSD issues is associated with the escalation of military conflicts worldwide. Complex biological mechanisms also play a significant role in the pathogenesis of PTSD, including those changes observed in the hippocampus and
Externí odkaz:
https://doaj.org/article/3c1741226cd74af6bb602a33a5d55d69
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background Given the inconsistencies in current studies regarding the impact of FKBP5 gene polymorphisms on depression, arising from variations in study methods, subjects, and treatment strategies, this paper provides a comprehensive review
Externí odkaz:
https://doaj.org/article/5e572134ecf34da69890a1260d658c28
Autor:
Guo Chen, Xinyuan Li, Xiang Zhou, Yang Li, Haitao Yu, Xiang Peng, Xuesong Bai, Chunlin Zhang, Zhenwei Feng, Yuhua Mei, Li Li, Yu Liu, Xin Gou, Yuanbin Jiang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The incidence of acute kidney injury (AKI) due to ischemia–reperfusion (IR) injury is increasing. There is no effective treatment for AKI, and because of this clinical challenge, AKI often progresses to chronic kidney disease, which is clo
Externí odkaz:
https://doaj.org/article/e61e7b93002a4af29dd24a276ad0ce9a
Publikováno v:
Stress, Vol 27, Iss 1 (2024)
AbstractPerinatal stress is associated with altered placental methylation, which plays a critical role in fetal development and infant outcomes. This proof-of-concept pilot study investigated the impact of lifetime trauma exposure and perinatal PTSD
Externí odkaz:
https://doaj.org/article/09b335bc345d4e55beb30336ef1cc439
Autor:
Sydney Rowson, Mandakh Bekhbat, Sean Kelly, Molly M. Hyer, Samya Dyer, David Weinshenker, Gretchen Neigh
Publikováno v:
Stress, Vol 27, Iss 1 (2024)
AbstractChronic stress exposure during development can have lasting behavioral consequences that differ in males and females. More specifically, increased depressive behaviors in females, but not males, are observed in both humans and rodent models o
Externí odkaz:
https://doaj.org/article/2c6c0a3909b0480e81ed8769067efb7e
Autor:
Maria Maiarù, Richard J. Acton, Eva L. Woźniak, Charles A. Mein, Christopher G. Bell, Sandrine M. Géranton
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Epigenetic changes can bring insight into gene regulatory mechanisms associated with disease pathogenicity, including chronicity and increased vulnerability. To date, we are yet to identify genes sensitive to epigenetic regulation
Externí odkaz:
https://doaj.org/article/41d2449ab5be4d6a83bfd42f7e60f74c
Publikováno v:
Electronic Journal of Biotechnology, Vol 65, Iss , Pp 24-44 (2023)
Background: The high disability rate of osteoarthritis (OA), a joint disease with an insidious onset and widespread effects, places a heavy financial burden on patients, families, and society. Traditional diagnostic approaches, including radiology an
Externí odkaz:
https://doaj.org/article/688be9256c2043e4b40c2e61366e128c
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