Výsledky vyhledávání

Akademický článek

Unlocking the Genetic Secrets of Acromegaly: Exploring the Role of Genetics in a Rare Disorder

Autor: Ioana Balinisteanu, Lavinia Caba, Andreea Florea, Roxana Popescu, Laura Florea, Maria-Christina Ungureanu, Letitia Leustean, Eusebiu Vlad Gorduza, Cristina Preda

Publikováno v: Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 9093-9121 (2024)

Acromegaly is a rare endocrine disorder characterized by the excessive production of growth hormone (GH) in adulthood. Currently, it is understood that certain pituitary neuroendocrine tumors (PitNETs) exhibit a hereditary predisposition. These tumor

Externí odkaz: https://doaj.org/article/b53c9e28ccd7456c81452098d88c379b

Zobrazit plný text záznamu

Akademický článek

Multi-Agent System Combined With Distributed Data Mining for Mutual Collaboration Classification

Autor: Mais Haj Qasem, Nadim Obeid, Amjad Hudaib, Mohammed Amin Almaiah, Ali Al-Zahrani, Ahmad Al-Khasawneh

Publikováno v: IEEE Access, Vol 9, Pp 70531-70547 (2021)

Distributed Data Mining (DDM) has been proposed as a means to deal with the analysis of distributed data, where DDM discovers patterns and implements prediction based on multiple distributed data sources. However, DDM faces several problems in terms

Externí odkaz: https://doaj.org/article/755bdd7a88b7457ab1a3a37261643c7e

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

AIP-mutated acromegaly resistant to first-generation somatostatin analogs: long-term control with pasireotide LAR in two patients

Autor: Adrian F Daly, Liliya Rostomyan, Daniela Betea, Jean-François Bonneville, Chiara Villa, Natalia S Pellegata, Beatrice Waser, Jean-Claude Reubi, Catherine Waeber Stephan, Emanuel Christ, Albert Beckers

Publikováno v: Endocrine Connections, Vol 8, Iss 4, Pp 367-377 (2019)

Acromegaly is a rare disease due to chronic excess growth hormone (GH) and IGF-1. Aryl hydrocarbon receptor interacting protein (AIP) mutations are associated with an aggressive, inheritable form of acromegaly that responds poorly to SST2-specific so

Externí odkaz: https://doaj.org/article/99d6a84e6ca34e03ae4397339330bbfb

Zobrazit plný text záznamu

Akademický článek

Circulating aryl hydrocarbon receptor-interacting protein (AIP) is independent of GH secretion

Autor: Marko Stojanovic, Zida Wu, Craig E Stiles, Dragana Miljic, Ivan Soldatovic, Sandra Pekic, Mirjana Doknic, Milan Petakov, Vera Popovic, Christian Strasburger, Márta Korbonits

Publikováno v: Endocrine Connections, Vol 8, Iss 4, Pp 326-337 (2019)

Background: Aryl hydrocarbon receptor-interacting protein (AIP) is evolutionarily conserved and expressed widely throughout the organism. Loss-of-function AIP mutations predispose to young-onset pituitary adenomas. AIP co-localizes with growth hormon

Externí odkaz: https://doaj.org/article/e57dfafa287449668177691133d77aa5

Zobrazit plný text záznamu

Akademický článek

AIP and MEN1 mutations and AIP immunohistochemistry in pituitary adenomas in a tertiary referral center

Autor: Adrian F Daly, David A Cano, Eva Venegas-Moreno, Patrick Petrossians, Elena Dios, Emilie Castermans, Alvaro Flores-Martínez, Vincent Bours, Albert Beckers, Alfonso Soto-Moreno

Publikováno v: Endocrine Connections, Vol 8, Iss 4, Pp 338-348 (2019)

Background: Pituitary adenomas have a high disease burden due to tumor growth/ invasion and disordered hormonal secretion. Germline mutations in genes such as MEN1 and AIP are associated with early onset of aggressive pituitary adenomas that can be r

Externí odkaz: https://doaj.org/article/5ba297d7db284cefb8f6d3bcf79c86e7

Zobrazit plný text záznamu