Zobrazeno 1 - 10
of 163
pro vyhledávání: '"FILIO BILLIA"'
Autor:
Vicki N. Wang, MD, Darshan H. Brahmbhatt, MB BChir, MD(Res), Julie K.K. Vishram-Nielsen, MD, PhD, Fernando L. Scolari, MD, PhD, Nicole L. Fung, Madison Otsuki, Vesna Mihajlovic, MD, Narmin Ibrahimova, Filio Billia, MD, PhD, Christopher B. Overgaard, MD, Adriana C. Luk, MD, MSc
Publikováno v:
CJC Open, Vol 6, Iss 11, Pp 1342-1350 (2024)
Background: Cardiogenic shock (CS) is a complex, life-threatening condition that requires timely care of patients. The purpose of this study is to evaluate the characteristics and outcomes of patients transferred to a cardiac intensive-care unit from
Externí odkaz:
https://doaj.org/article/adc018a8b76f418498fa6fdf72d086ad
Autor:
Luigi Colarusso, Darshan H. Brahmbhatt, Fernando L. Scolari, Kristine A. Keon, Emily Shin, Ava I. De Pellegrin Overgaard, Mahrukh Nisar, Nicole Fung, Narmin Ibrahimova, Filio Billia, Christopher B. Overgaard, Adriana C. Luk
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 3023-3032 (2024)
Abstract Background Cardiogenic shock (CS) is associated with high in‐hospital mortality. Objective assessment of its severity and prognosis is paramount for timely therapeutic interventions. This study aimed to evaluate the efficacy of the shock i
Externí odkaz:
https://doaj.org/article/cd5af78e0b1e43cc9fc92152746fa095
Autor:
Julie K.K. Vishram-Nielsen, MD, PhD, Fernando Luis Scolari, MD, PhD, Chun-Po Steve Fan, PhD, Yas Moayedi, MD, Heather J. Ross, MD, MHSc, Cedric Manlhiot, PhD, Melissa A. Allwood, MD, PhD, Ana Carolina Alba, MD, PhD, Keith R. Brunt, PhD, Jeremy A. Simpson, PhD, Filio Billia, MD, PhD
Publikováno v:
CJC Open, Vol 6, Iss 5, Pp 745-754 (2024)
Background: Diaphragm atrophy can contribute to dyspnea in patients with heart failure (HF) with its link to central neurohormonal overactivation. HF medications that cross the blood-brain barrier could act centrally and improve respiratory function,
Externí odkaz:
https://doaj.org/article/833a36761fe34a46a519f4e099cc39aa
Autor:
Yanan Zhao, Beibei Du, Praloy Chakraborty, Nathan Denham, Stéphane Massé, Patrick F.H. Lai, Mohammed Ali Azam, Filio Billia, Paaladinesh Thavendiranathan, Husam Abdel‐Qadir, Gary D. Lopaschuk, Kumaraswamy Nanthakumar
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background We recently demonstrated that acute administration of ibrutinib, a Bruton's tyrosine kinase inhibitor used in chemotherapy for blood malignancies, increases ventricular arrhythmia (VA) vulnerability. A pathway of ibrutinib‐induced vulner
Externí odkaz:
https://doaj.org/article/b2f674f7a00f4bfabfc90509645f8705
Autor:
Frank Yu, MSc, Roberto Ribeiro, MD, PhD, Roizar Rosales, MD, Ludger Hauck, PhD, Daniela Grothe, Juglans Alvarez, MD, Mitchell Adamson, MSc, Vivek Rao, MD, PhD, Mitesh Badiwala, MD, PhD, Filio Billia, MD, PhD
Publikováno v:
JHLT Open, Vol 4, Iss , Pp 100074- (2024)
Background: Ex situ heart perfusion (ESHP) has been used to optimize donor organs before heart transplantation. However, cardiac function often deteriorates with the development of myocardial edema. The use of dialysis during ESHP could assist in car
Externí odkaz:
https://doaj.org/article/6779d26f4d9b419e86353ba7841e728a
Autor:
Sabri Soussi, Claudia dos Santos, Jacob C. Jentzer, Alexandre Mebazaa, Etienne Gayat, Janine Pöss, Hannah Schaubroeck, Filio Billia, John C. Marshall, Patrick R. Lawler
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Circulatory shock is defined syndromically as hypotension associated with tissue hypoperfusion and often subcategorized according to hemodynamic profile (e.g., distributive, cardiogenic, hypovolemic) and etiology (e.g., infection, myocardial
Externí odkaz:
https://doaj.org/article/0fc7c390b1824d438226e300f9975299
Autor:
Eduard Rodenas‐Alesina, Fernando Luis Scolari, Vicki N. Wang, Darshan H. Brahmbhatt, Vesna Mihajlovic, Nicole L. Fung, Madison Otsuki, Filio Billia, Christopher B. Overgaard, Adriana Luk
Publikováno v:
ESC Heart Failure, Vol 10, Iss 4, Pp 2577-2587 (2023)
Abstract Aims Studies in cardiogenic shock (CS) often have a heterogeneous population of patients, including those with acute myocardial infarction and acute decompensated heart failure (ADHF‐CS). The therapeutic profile of milrinone may benefit pa
Externí odkaz:
https://doaj.org/article/649db6ee4f8548099dbed5ca276e228f
Autor:
Keith Dadson, PhD, Paaladinesh Thavendiranathan, MD, SM, Ludger Hauck, PhD, Daniela Grothe, Mohammed Ali Azam, MBBS, PhD, Shanna Stanley-Hasnain, MSc, Donya Mahiny-Shahmohammady, BSc, Daoyuan Si, MD, PhD, Mahmoud Bokhari, MD, Patrick F.H. Lai, MSc, Stéphane Massé, MASc, Kumaraswamy Nanthakumar, MD, Filio Billia, MD, PhD
Publikováno v:
CJC Open, Vol 4, Iss 12, Pp 1043-1052 (2022)
Background: Doxorubicin-induced cardiomyopathy (DICM) is one of the complications that can limit treatment for a significant number of cancer patients. In animal models, the administration of statins can prevent the development of DICM. Therefore, th
Externí odkaz:
https://doaj.org/article/c86b0b14759e4a9d902608a4ef2a3376
Autor:
Aws Almufleh, MBBS, MPH, FRCPC, Ricky D. Turgeon, BSc (Pharm), ACPR, PharmD, Anique Ducharme, MD, MSc, FRCPC, Filio Billia, MD, PhD, FRCPC, Justin Ezekowitz, MD, MBBCh, MSc, FRCPC
Publikováno v:
CJC Open, Vol 4, Iss 10, Pp 866-872 (2022)
Background: The suboptimal implementation of guideline-directed medical therapy (GDMT) for heart failure (HF) patients has been linked with poor clinical outcomes. Little is known about the potential role of cardiology residency training programs in
Externí odkaz:
https://doaj.org/article/70657c1077de428198fa83f4ec46e6d6
Autor:
Veera Ganesh Yerra, Sri Nagarjun Batchu, Harmandeep Kaur, MD Golam Kabir, Youan Liu, Suzanne L. Advani, Duc Tin Tran, Shadi Sadeghian, Phelopater Sedrak, Filio Billia, Uros Kuzmanov, Anthony O. Gramolini, Deema O. Qasrawi, Evgeniy V. Petrotchenko, Christoph H. Borchers, Kim A. Connelly, Andrew Advani
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Inflammation promotes adverse ventricular remodeling, a common antecedent of heart failure. Here, we set out to determine how inflammatory cells affect cardiomyocytes in the remodeling heart. Pathogenic cardiac macrophages induced an IFN response in
Externí odkaz:
https://doaj.org/article/0c5911e4a2bf433aac0c14bc3122354f