Zobrazeno 1 - 10
of 75
pro vyhledávání: '"FIASMA"'
Autor:
Susann Kummer, Angelika Lander, Jonas Goretzko, Norman Kirchoff, Ursula Rescher, Sebastian Schloer
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 195-207 (2022)
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus (EBOV). The latest occasional EVD outbreak (2013–2016) in Western African, which was accompanied by a high fatality rate, showed the great potential of epidem
Externí odkaz:
https://doaj.org/article/673fa9eaf29b4e8e97536ec71e50e379
Autor:
Nicolas Hoertel, Katayoun Rezaei, Marina Sánchez-Rico, Alfonso Delgado-Álvarez, Johannes Kornhuber, Erich Gulbins, Mark Olfson, Charles Ouazana-Vedrines, Alexander Carpinteiro, Céline Cougoule, Katrin Anne Becker, Jesús M. Alvarado, Frédéric Limosin, on behalf of the AP-HP/Université Paris Cité/INSERM COVID-19 Research Collaboration, AP-HP COVID CDR Initiative and “Entrepôt de Données de Santé” AP-HP Consortium
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1107 (2023)
Prior evidence indicates the potential central role of the acid sphingomyelinase (ASM)/ceramide system in the infection of cells with SARS-CoV-2. We conducted a multicenter retrospective observational study including 72,105 adult patients with labora
Externí odkaz:
https://doaj.org/article/71a90dcb88054f20b5877d034930daa3
Autor:
Sebastian Schloer, Linda Brunotte, Jonas Goretzko, Angeles Mecate-Zambrano, Nadia Korthals, Volker Gerke, Stephan Ludwig, Ursula Rescher
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2245-2255 (2020)
ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic caused by the Severe Acute Respiratory Syndrome Related Coronavirus 2 (SARS-CoV-2) is a global health emergency. As only very limited therapeutic options are clinically available, there is an u
Externí odkaz:
https://doaj.org/article/bcf82b4bf73a42dcb504646c60eb279b
Autor:
Murad Abusukhun, Martin S. Winkler, Stefan Pöhlmann, Onnen Moerer, Konrad Meissner, Björn Tampe, Heike Hofmann-Winkler, Michael Bauer, Markus H. Gräler, Ralf A. Claus
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Effective treatment strategies for severe coronavirus disease (COVID-19) remain scarce. Hydrolysis of membrane-embedded, inert sphingomyelin by stress responsive sphingomyelinases is a hallmark of adaptive responses and cellular repair. As demonstrat
Externí odkaz:
https://doaj.org/article/ffd281b80d554c438e499f3120e6ff91
Autor:
Ha-Yeun Chung, Ralf A. Claus
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
Breakdown of the inert and constitutive membrane building block sphingomyelin to the highly active lipid mediator ceramide by extracellularly active acid sphingomyelinase is tightly regulated during stress response and opens the gate for invading pat
Externí odkaz:
https://doaj.org/article/8279985826df45b69206a1df962ecebb
Akademický článek
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Autor:
Marina Sánchez-Rico, Frédéric Limosin, Raphaël Vernet, Nathanaël Beeker, Antoine Neuraz, Carlos Blanco, Mark Olfson, Cédric Lemogne, Pierre Meneton, Christel Daniel, Nicolas Paris, Alexandre Gramfort, Guillaume Lemaitre, Pedro De La Muela, Elisa Salamanca, Mélodie Bernaux, Ali Bellamine, Anita Burgun, Nicolas Hoertel, on behalf of AP-HP/Université de Paris/INSERM COVID-19 Research Collaboration/AP-HP COVID CDR Initiative/“Entrepôt de Données de Santé” AP-HP Consortium
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 24, p 5891 (2021)
(1) Background: Based on its antiviral activity, anti-inflammatory properties, and functional inhibition effects on the acid sphingomyelinase/ceramide system (FIASMA), we sought to examine the potential usefulness of the H1 antihistamine hydroxyzine
Externí odkaz:
https://doaj.org/article/2c111d8ee8bf47dab71b92074cd8cd23
Autor:
Johannes Kornhuber, Erich Gulbins
Publikováno v:
Pharmaceuticals, Vol 14, Iss 9, p 894 (2021)
Major depressive disorder (MDD) is a common and severe mental disorder that is usually recurrent and has a high risk of suicide. This disorder manifests not only with psychological symptoms but also multiple changes throughout the body, including inc
Externí odkaz:
https://doaj.org/article/cef55aed28a145f7aca9cdd500540b88
Akademický článek
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Akademický článek
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