Zobrazeno 1 - 10
of 4 829
pro vyhledávání: '"FGF23"'
Autor:
Eduardo Jorge Duque, Gustavo Fernandes Ferreira, Ivone Braga Oliveira, Wagner Dominguez, Fabiana Agena, Vanda Jorgetti, Francine Lemos, Myles Wolf, Elias David-Neto, Rosa Maria A. Moysés
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background Living kidney donors (LKD) experience an abrupt decline in glomerular filtration rate (GFR) resulting in abnormalities of mineral and bone metabolism (MBD), and this may have implications for skeletal health. We prospectively stud
Externí odkaz:
https://doaj.org/article/0e96ce2f1d6248d3a26a56cbce3a0c95
Publikováno v:
FEBS Open Bio, Vol 14, Iss 10, Pp 1691-1700 (2024)
Renal αKlotho along with fibroblast growth factor 23 regulates phosphate and vitamin D metabolism. Its cleavage yields soluble Klotho controlling intracellular processes. αKlotho has anti‐inflammatory and antioxidant effects and is nephro‐ and
Externí odkaz:
https://doaj.org/article/e667f172159f4135b188f2bb6388fb67
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Steroid-induced osteonecrosis of the femoral head (SONFH) is the predominant cause of non-traumatic osteonecrosis of the femoral head (ONFH). Impaired blood supply and reduced osteogenic activity of the femoral head are the key pathogenic me
Externí odkaz:
https://doaj.org/article/95f8227a2af34e5ab6c1e38ed061c82e
Publikováno v:
Hearts, Vol 5, Iss 2, Pp 211-224 (2024)
Heart failure with preserved ejection fraction (HFpEF) is a major health concern. There is a growing recognition of the causal interplay between arterial stiffness and HFpEF. We recently reported that phosphate retention is a trigger for arterial sti
Externí odkaz:
https://doaj.org/article/431da8d8d2894a028e7f31d4493c6b58
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Compelling evidence suggests that calcium/phosphorus homeostasis-related parameters may be linked to diabetes mellitus and cardiovascular events. However, few studies have investigated the association of fibroblast growth factor 2
Externí odkaz:
https://doaj.org/article/ad81883634b4452e97872565f4dbd34d
Akademický článek
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Autor:
Stephanie Vermeulen, Mirjam E. A. Scheffer‐Rath, Martine T. P. Besouw, Amarens van derVaart, Martin H. deBorst, Annemieke M. Boot
Publikováno v:
Journal of Diabetes, Vol 16, Iss 6, Pp n/a-n/a (2024)
Abstract Background Cardiovascular disease (CVD) is the major cause of mortality in type 1 diabetes (T1D). The objective of this study is to evaluate fibroblast growth factor 23 (FGF23) and calcium‐phosphate metabolism in relation to cardiovascular
Externí odkaz:
https://doaj.org/article/b06f4e9a79194cc181aa678a969771fa
Autor:
Ana M. Valdes, Adeel Ikram, Lauren A. Taylor, Amy Zheng, Afroditi Kouraki, Anthony Kelly, Waheed Ashraf, Amrita Vijay, Suzanne Miller, Jessica Nightingale, Nicholas M. Selby, Benjamin J. Ollivere
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHip fractures in frail patients result in excess mortality not accounted for by age or comorbidities. The mechanisms behind the high risk of mortality remain undetermined but are hypothesized to be related to the inflammatory status of frai
Externí odkaz:
https://doaj.org/article/2d8827e73ea04aca82361fe79e3edd1d
Autor:
Isaac Campos, Beatrice Richter, Sarah Madison Thomas, Brian Czaya, Christopher Yanucil, Dominik Kentrup, Abul Fajol, Qing Li, Stephen M. Secor, Christian Faul
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 11, Iss 10, p 320 (2024)
Fibroblast growth factor (FGF) 23 is a bone-derived hormone that promotes renal phosphate excretion. Serum FGF23 is increased in chronic kidney disease (CKD) and contributes to pathologic cardiac hypertrophy by activating FGF receptor (FGFR) 4 on car
Externí odkaz:
https://doaj.org/article/2e51a25aa686470b905f7306364beafd
Autor:
Lisanne Brueck, Sascha Roocke, Veronika Matschke, Annette Richter-Unruh, Katrin Marcus-Alic, Carsten Theiss, Sarah Stahlke
Publikováno v:
Cells, Vol 13, Iss 18, p 1515 (2024)
Our study investigates the impact of FGF23 overexpression on SaOS-2 cells to elucidate its role in cellular stress and morphology, contributing to the understanding of skeletal pathologies like X-linked hypophosphatemia (XLH). Using transmission elec
Externí odkaz:
https://doaj.org/article/0ba2d1a10db546899059638b78d0a225