Zobrazeno 1 - 10
of 85
pro vyhledávání: '"FGF21, Fibroblast growth factor 21"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/02b5868a15ce4f9eb9a4dacf48a32c5f
Autor:
Hong Zhu, Jie Xu, Min Zhao, Hangqi Luo, Minjie Lin, Yuting Luo, Yuan Li, Huacheng He, Jiang Wu
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
As conventional treatments for diabetic wounds often fail to achieve rapid satisfactory healing, the development of effective strategies to accelerate diabetic wound repair is highly demanded. Herein, fibroblast growth factor 21 (FGF21) and metformin
Externí odkaz:
https://doaj.org/article/7b6811beb3dd484c90da0aead554aaf8
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Mice with hepatocyte-specific deletion of autophagy-related 7 (Atg7ΔHep mice) develop hepatoma, suggesting that autophagy deficiency could be a factor in the initiation of tumorigenesis. We have shown that FGF21 is induced as a ‘mitokine’ when A
Externí odkaz:
https://doaj.org/article/10e9b539b8bc49b59ca7dfa95c19ec46
Autor:
Guillaume Bourdon, Anthony Estienne, Claire Chevaleyre, Christelle Ramé, Fabrice Guérif, Jean-Sébastien Brun, Claudine Vasseur, Gaelle Fromont, Ingrid Plotton, Diane Dufour-Rainfray, Erika Caldas-Silveira, Joëlle Dupont, Pascal Froment, Pierre-Henri Ducluzeau
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Lifestyle, environment and excess body weight are not only associated with an increased risk of metabolic disorders, such as type 2 diabetes, but also to other pathological processes, such as infertility. A hormone produced mainly by the liver called
Externí odkaz:
https://doaj.org/article/1121dad6512449618274ff10916d7f85
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Background: Maternal high-fat diet (MHFD) has been shown to increase susceptibility to neurological disease in later offspring, but the underlying mechanism is not clear. Fibroblast growth factor 21 (FGF21) has been reported to have a neuroprotective
Externí odkaz:
https://doaj.org/article/a40409428ecc4ba28e766c1ce7a9d895
Autor:
Jiamin Li, Yuanshi Li, Yining Liu, Hang Yu, Ning Xu, Di Huang, Yadong Xue, Sijia Li, Haixin Chen, Jiali Liu, Qingsui Li, Yiming Zhao, Ronghao Zhang, Hongru Xue, Yuehang Sun, Ming Li, Pengyu Li, Mingbin Liu, Zhen Zhang, Xin Li, Weijie Du, Ning Wang, Baofeng Yang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Infarcted myocardium is predisposed to cause lethal ventricular arrhythmias that remain the main cause of death in patients suffering myocardial ischemia. Liver-derived fibroblast growth factor 21 (FGF21) is an endocrine regulator, which exerts metab
Externí odkaz:
https://doaj.org/article/0010fdb7e79b4f0f8ec1c08510d453fe
Autor:
Banrida Wahlang, Monika Thapa, Michael L. Merchant, Jian Jin, Sudhir Srivastava, Josiah E. Hardesty, Russell A. Prough, Shesh N. Rai, Matthew C. Cave, Kimberly Z. Head
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3806-3819 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Dioxin-like molecules have been associated with endocrine disruption and liver disease. To better understand aryl hydrocarbon receptor (AHR) biology, metabolic phenotyping and liver proteomics were performed in mice following ligand-activation or who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd0117be990219f236c36406e5afea7
https://doi.org/10.1016/j.apsb.2021.10.014
https://doi.org/10.1016/j.apsb.2021.10.014
Autor:
Yatrik M. Shah, Shogo Takahashi, Sadeesh K. Ramakrishnan, Raja Gopal Reddy Mooli, Frank J. Gonzalez, Sumeet Solanki, Jessica Rodriguez
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 585-597 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Fatty liver or nonalcoholic fatty liver disease (NAFLD) is the most common liver disease associated with comorbidities such as insulin resistance and cardiovascular and metabolic diseases. Chronic activation of hypoxic signaling, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d8ab9d3e6c8736a8ba6e7154654a18
https://doi.org/10.1016/j.jcmgh.2021.03.011
https://doi.org/10.1016/j.jcmgh.2021.03.011
Autor:
Carlos Jose Pirola, Adrian Salatino, Maria Florencia Quintanilla, Gustavo Osvaldo Castaño, Martin Garaycoechea, Silvia Sookoian
Publikováno v:
EBioMedicine, Vol 76, Iss, Pp 103858-(2022)
EBioMedicine
EBioMedicine
Summary Background Human body microbiotas are influenced by several factors, including the interaction of the host with the environment and dietary preferences. The role of host genetics in modulating the liver microbiota in the context of NAFLD rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4440e3a11be1e15f228774d5b112786e
http://www.sciencedirect.com/science/article/pii/S2352396422000421
http://www.sciencedirect.com/science/article/pii/S2352396422000421
Autor:
Tirthadipa Pradhan-Sundd
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1199-1201 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1199-1201 (2021)
Background & Aims cAMP responsive element-binding protein 3 like 3 (CREB3L3) is a membrane-bound transcription factor involved in the maintenance of lipid metabolism in the liver and small intestine. CREB3L3 controls hepatic triglyceride and glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b659cdeaf5713387b2f5a214c940ddf
https://doi.org/10.1016/j.jcmgh.2021.01.002
https://doi.org/10.1016/j.jcmgh.2021.01.002