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Akademický článek

Localized Phosphorylation of a Kinesin-1 Adaptor by a Capsid-Associated Kinase Regulates HIV-1 Motility and Uncoating

Autor: Viacheslav Malikov, Mojgan H. Naghavi

Publikováno v: Cell Reports, Vol 20, Iss 12, Pp 2792-2799 (2017)

Although microtubule motors mediate intracellular virus transport, the underlying interactions and control mechanisms remain poorly defined. This is particularly true for HIV-1 cores, which undergo complex, interconnected processes of cytosolic trans

Externí odkaz: https://doaj.org/article/5b4f01a23de04e23aa3149d971868744

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Akademický článek

The effects of lack of melatonin in experimental rat model of Alzheimers Disease: relationship with FEZ1 gene expression

Autor: Mehmet Demir, Umit Yilmaz, Cemil Colak, Yilmaz Cigremis, Fatma Ozyalin, Ibrahim Tekedereli, Ayten Kilincli, Suleyman Sandal

Publikováno v: Medicine Science, Vol 6, Iss 2, Pp 217-23 (2017)

Alzheimers Disease (AD), which is the most common reason for dementia, is an irreversible neurodegenerative brain disease. FEZ1 is a protein expressed in the brain. High expressions of FEZ1 mRNA have been interpreted as an indicator of high neural pl

Externí odkaz: https://doaj.org/article/eab3ec8895e748e4bfac41075961f7ce

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Akademický článek

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Akademický článek

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Akademický článek

Investigation of Fasciculation and Elongation Protein ζ-1 (FEZ1) in Peripheral Blood Reveals Differences in Gene Expression in Patients with Schizophrenia

Autor: Vachev T.I., Stoyanova V.K., Ivanov H.Y., Minkov I.N., Popov N.T.

Publikováno v: Balkan Journal of Medical Genetics, Vol 18, Iss 1, Pp 31-38 (2015)

Schizophrenia (SZ) is a chronic neuropsychiatric disorder characterized by affective, neuromorphological and cognitive impairment, deteriorated social functioning and psychosis with underlying molecular abnormalities, including gene expression change

Externí odkaz: https://doaj.org/article/0951541a678a4b969e0dde3dad23e41c

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Akademický článek

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Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice

Autor: Hongxin Zhu, Xiao-Li Tian, Qiang Li, Sheng Li, Gil Alterovitz, Shiwei Duan, Mingqing Xu, Xinhui Wang, Fudi Wang, Xinzhi Zhao, Fuquan Zhang, Xinyue Lu, Huimin Li

Publikováno v: Aging (Albany NY)

Background: Aging has often been linked to age-related vascular disorders. The elucidation of the putative genes and pathways underlying vascular aging likely provides useful insights into vascular diseases at advanced ages. Transcriptional regulator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3cb895f43f8e52cd704a045c465aaf6
https://doi.org/10.18632/aging.102275

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Fasciculation and elongation zeta proteins 1 and 2: From structural flexibility to functional diversity

Autor: Jörg Kobarg, Mariana Teixeira, Marcos Rodrigo Alborghetti

Publikováno v: World Journal of Biological Chemistry

Fasciculation and elongation zeta/zygin (FEZ) proteins are a family of hub proteins and share many characteristics like high connectivity in interaction networks, they are involved in several cellular processes, evolve slowly and in general have intr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4aef7f164148198a9e4318a2b20642c
https://doi.org/10.4331/wjbc.v10.i2.28

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Is there a new pathway relationship between melatonin and FEZ1 in experimental rat model of Alzheimer’s disease?

Autor: Suleyman Sandal, M Demir, Cemil Colak, İbrahim Tekedereli, Fatma Ozyalin, U Yilmaz, Yilmaz Cigremis

Publikováno v: Bratislava Medical Journal. 120:70-77

Alzheimer's disease (AD) is a progressive neurodegenerative disease. This study was performed to determine the possible relationship between melatonin, which is known to play a role in the neuro-protective mechanism in AD, and fasciculation and elong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b507d8de0b193f284f57f77fb27aa2f
https://doi.org/10.4149/bll_2019_011

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Schizophrenia risk ZNF804A interacts with its associated proteins to modulate dendritic morphology and synaptic development

Autor: Joseph Mao, Fengping Dong, Joy Yoon, Yingwei Mao, Miranda Chen

Publikováno v: Molecular Brain
Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)

Schizophrenia (SZ) is a devastating brain disease that affects about 1% of world population. Among the top genetic associations,zinc finger protein 804A(ZNF804A) gene encodes a zinc finger protein, associated with SZ and biolar disorder (BD). Copy nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1731080ef69256ebfd37a7b8c08d38ea
http://europepmc.org/articles/PMC7809827

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