Use of Combinatorial and Multiple Parallel Synthesis Methodologies for the Development of Antiinfective Natural Products.

Autor: Fecik, R. A.¹, Frank, K. E.¹, Gentry, E. J.¹, Mitscher, L. A.¹, Shibatam, M.¹

Publikováno v: Revista Cubana de Química. 2000, Vol. 12 Issue 1, p3-9. 7p.

Chiral DNA Gyrase Inhibitors. 3. Probing the Chiral Preference of the Active Site of DNA Gyrase. Synthesis of 10-Fluoro-6-methyl-6,7-dihydro-9-piperazinyl- 2H-benzo[a]quinolizin-20-one-3-carboxylic Acid Analogues

Autor: Fecik, R. A., Devasthale, P., Pillai, S., Keschavarz-Shokri, A., Shen, L., Mitscher, L. A.

Publikováno v: Journal of Medicinal Chemistry; February 2005, Vol. 48 Issue: 4 p1229-1236, 8p

Fatty acid amide hydrolase substrate specificity

Autor: Boger, D. L., Fecik, R. A., Patterson, J. E., Miyauchi, H., Patricelli, M. P., Cravatt, B. F.

Publikováno v: Bioorganic & Medicinal Chemistry Letters; 2000, Vol. 10 Issue: 23 p2613-2616, 4p

ChemInform Abstract: The Search for Orally Active Medications Through Combinatorial Chemistry.

Autor: FECIK, R. A., FRANK, K. E., GENTRY, E. J., MENON, S. R., MITSCHER, L. A., TELIKEPALLI, H.

Publikováno v: ChemInform; Aug1998, Vol. 29 Issue 31, pno-no, 1p

Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide.

Autor: Boger DL; Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. boger@scripps.edu, Sato H, Lerner AE, Hedrick MP, Fecik RA, Miyauchi H, Wilkie GD, Austin BJ, Patricelli MP, Cravatt BF

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2000 May 09; Vol. 97 (10), pp. 5044-9.