Zobrazeno 1 - 10
of 212
pro vyhledávání: '"FDA, the Food and Drug Administration"'
Publikováno v:
Indian Business Case Studies Volume I, 2022.
Externí odkaz:
https://doi.org/10.1093/oso/9780192869371.003.0011
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1567-1590
HIV reverse transcriptase (RT) inhibitors are the important components of highly active antiretroviral therapies (HAARTs) for anti-HIV treatment and pre-exposure prophylaxis in clinical practice. Many RT inhibitors and their combination regimens have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef424a5c6c813905e85108700bf093a5
https://doi.org/10.1016/j.apsb.2021.11.009
https://doi.org/10.1016/j.apsb.2021.11.009
Autor:
John B. Hagan, MD, Elizabeth Ender, MD, Rohit D. Divekar, MBBS, PhD, Thanai Pongdee, MD, Matthew A. Rank, MD
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 6, Iss 1, Pp 69-76 (2022)
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 6, Iss 1, Pp 69-76 (2022)
Objective: To estimate the potential risk for a future postmarket black box warning (BBW) of US Food and Drug Administration (FDA)-approved monoclonal antibodies (mAbs) because of the importance for medical clinicians to understand mAb risks and bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401b96e5615755d7c31a16937dafc148
https://doi.org/10.1016/j.mayocpiqo.2021.11.009
https://doi.org/10.1016/j.mayocpiqo.2021.11.009
Publikováno v:
JACC: Basic to Translational Science
Highlights • Knowledge of the genetic etiologies of cardiomyopathies has created novel opportunities for treatments. • Emerging treatments targets include gene therapy, myofilament function, protein quality control, and metabolism. • Considerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c656f79b564e9e437a00ca02b88041ed
https://doi.org/10.1016/j.jacbts.2021.07.012
https://doi.org/10.1016/j.jacbts.2021.07.012
Autor:
Gail A. Van Norman
Publikováno v:
JACC: Basic to Translational Science
Summary Phase I and II clinical trials increasingly combine therapeutic and toxicity endpoints. Recently, therapeutic agents have even achieved U.S. Food and Drug Agency approval based on early phase trials alone. These developments point to new chal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e17e57e5b0cd0a23203803446e8792
https://doi.org/10.1016/j.jacbts.2021.09.005
https://doi.org/10.1016/j.jacbts.2021.09.005
Autor:
Xianglin Zhang, Qi Zhang, Wenqing Tian, Chunqing Meng, Xiaodong Guo, Tingfang Sun, Keda Yu, Qiuyue Ding, Zekang Xiong, Bin Wu, Wancheng Zhang
Publikováno v:
Bioactive Materials, Vol 6, Iss 11, Pp 4163-4175 (2021)
Bioactive Materials
Bioactive Materials
In situ tissue engineering is a powerful strategy for the treatment of bone defects. It could overcome the limitations of traditional bone tissue engineering, which typically involves extensive cell expansion steps, low cell survival rates upon trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2598d49223c891cdcd36fd9c9afab4a6
http://www.sciencedirect.com/science/article/pii/S2452199X21001821
http://www.sciencedirect.com/science/article/pii/S2452199X21001821
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2469-2487 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Lipid-based formulations (LBFs) have demonstrated a great potential in enhancing the oral absorption of poorly water-soluble drugs. However, construction of in vitro and in vivo correlations (IVIVCs) for LBFs is quite challenging, owing to a complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b31a53f79e1ed99a94fbe16d77554c
https://doi.org/10.1016/j.apsb.2021.03.025
https://doi.org/10.1016/j.apsb.2021.03.025
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2416-2448 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2416-2448 (2021)
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules than small molecular drugs due to their high selectivity and efficacy, but fewer side effects. Owing to the poor stability and limited permeability through gastro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6732d4326595a5ad29955ebaff92173
https://doi.org/10.1016/j.apsb.2021.04.001
https://doi.org/10.1016/j.apsb.2021.04.001
Publikováno v:
Bioactive Materials
Bioactive Materials, Vol 6, Iss 7, Pp 1973-1987 (2021)
Bioactive Materials, Vol 6, Iss 7, Pp 1973-1987 (2021)
The tumor development and metastasis are closely related to the structure and function of the tumor microenvironment (TME). Recently, TME modulation strategies have attracted much attention in cancer immunotherapy. Despite the preliminary success of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9e3a12774af1e45fb188f205ad9bdc
https://doi.org/10.1016/j.bioactmat.2020.12.010
https://doi.org/10.1016/j.bioactmat.2020.12.010
Publikováno v:
Mayo Clinic Proceedings
The coronavirus disease 2019 (COVID-19) pandemic has rapidly created widespread impacts on global health and the economy. Data suggest that women are less prone to severe illness; however, sex-disaggregated data are incomplete, leaving room for misin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c01733e2d4f7d86a2a2e4ef79f918b8
https://doi.org/10.1016/j.mayocp.2021.04.009
https://doi.org/10.1016/j.mayocp.2021.04.009