Zobrazeno 1 - 10
of 37
pro vyhledávání: '"FDA, United States Food and Drug Administration"'
Autor:
Eric Macy, Shalin Pandya, Javed Sheikh, Amber Burnette, Jiaxiao M. Shi, Joanie Chung, Nancy Gin, William Crawford, Jing Zhang
Publikováno v:
The Journal of Allergy and Clinical Immunology. in Practice
Background COVID-19 mRNA vaccination-associated acute-onset hypersensitivity reactions have caused anxiety and may be contributing to vaccine hesitancy. Objective Determine the incidence, severity, and risk factors for treated acute-onset COVID-19 mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4940a3d7675f37b8eeb14dbcc07a5bfb
https://doi.org/10.1016/j.jaip.2021.12.021
https://doi.org/10.1016/j.jaip.2021.12.021
Autor:
Andrew P, Cap
Publikováno v:
Chest
Background Pulmonary vascular microthrombi are a proposed mechanism of COVID19 respiratory failure. We hypothesized that early administration of tissue-plasminogen activator(tPA) followed by therapeutic heparin would improve pulmonary function in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499c3a7c368a3ca1e8c0249cca23364d
http://europepmc.org/articles/PMC8767759
http://europepmc.org/articles/PMC8767759
Autor:
Natalie E. Dean, Kourtney Davis, M. Elizabeth Halloran, Zachary J. Madewell, Jesse A. Berlin, Paul Coplan, Claudio J. Struchiner
Publikováno v:
Epidemics, Vol 37, Iss, Pp 100506-(2021)
Epidemics
Epidemics
Outbreaks of emerging pathogens pose unique methodological and practical challenges for the design, implementation, and evaluation of vaccine efficacy trials. Lessons learned from COVID-19 highlight the need for innovative and flexible study design a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3984dd5d66efb42710d8c047b02eb36
http://www.sciencedirect.com/science/article/pii/S1755436521000554
http://www.sciencedirect.com/science/article/pii/S1755436521000554
Publikováno v:
Biochemistry and Biophysics Reports
Oxidative damage to lens epithelial cells plays an important role in the development of age-related cataract, and the health of the lens has important implications for overall ocular health. As a result, there is a need for effective therapeutic agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6ad6a048992849fbae63780b9c9e9c3
https://pubmed.ncbi.nlm.nih.gov/35128081
https://pubmed.ncbi.nlm.nih.gov/35128081
Autor:
Raj Vuppalanchi, Mary F. Paine, Robin J. Marles, Steven J. Casper, Leonard B. Seeff, Bill J. Gurley, Hellen A. Oketch-Rabah, Tieraona Low Dog, Amy L. Roe, Jawad Ahmad, Scott A. Jordan, Gabriel I. Giancaspro, Andrew Stolz, Cynthia V. Rider, Christopher Koh, Richard Ko, Averell H. Sherker, Kan He, Jose Serrano, Robert J. Fontana, Herbert L. Bonkovsky, Víctor M. Navarro, Joseph M. Betz, Theertham P. Rao, Simona Rossi, Mahendra P. Kapoor
Publikováno v:
Toxicology Reports, Vol 7, Iss, Pp 386-402 (2020)
Toxicology Reports
Toxicology Reports
As part of the United States Pharmacopeia’s ongoing review of dietary supplement safety data, a new comprehensive systematic review on green tea extracts (GTE) has been completed. GTEs may contain hepatotoxic solvent residues, pesticide residues, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0d82c68321543dfc2fccf506f4b9cc
http://www.sciencedirect.com/science/article/pii/S2214750019306596
http://www.sciencedirect.com/science/article/pii/S2214750019306596
Publikováno v:
Advanced Drug Delivery Reviews
Current preclinical studies in drug development utilize high-throughput in vitro screens to identify lead drug candidates, followed by both in vitro and in vivo models to predict lead candidates' pharmacokinetic and pharmacodynamic properties. The go
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27450d16dc16ed032dd279f5267ef128
https://doi.org/10.1016/j.addr.2020.09.012
https://doi.org/10.1016/j.addr.2020.09.012
Autor:
Rabindra R. Watson, Arvind J. Trindade, Kuman Krishnan, Guru Trikudanathan, Allison R. Schulman, Joshua Melson, Udayakumar Navaneethan, John T. Maple, Rahul Pannala, Harry R. Aslanian, David R. Lichtenstein, Mansour A. Parsi, Manoop S. Bhutani, Amrita Sethi
Publikováno v:
VideoGIE
Background Endoscopic intervention is often the first line of therapy for GI nonvariceal bleeding. Although some of the devices and techniques used for this purpose have been well studied, others are relatively new, with few available outcomes data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92246eaa939cbd230892446ffad4ea0c
https://doi.org/10.1016/j.vgie.2019.02.004
https://doi.org/10.1016/j.vgie.2019.02.004
Publikováno v:
Applied Materials Today
Highlights • Nitric oxide gas and donors are promising candidates for antiviral therapies. • Combined with dual antimicrobial and antithrombotic properties. • Emerging therapies are undergoing clinical trials. • Potential to develop medical d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3549bc09a794687347a5219e98002bdc
Publikováno v:
Contemporary Clinical Trials Communications
Contemporary Clinical Trials Communications, Vol 19, Iss, Pp 100601-(2020)
Contemporary Clinical Trials Communications, Vol 19, Iss, Pp 100601-(2020)
Background: Hepatitis B virus (HBV) infection is an important etiology for chronic hepatitis globally, and especially so in China. HBV infection can lead to the development of cirrhosis through the pathological process of liver fibrosis. The effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6512a13cbe689af21cf6786f7ddafb1d
http://europepmc.org/articles/PMC7334581
http://europepmc.org/articles/PMC7334581
Publikováno v:
Ecotoxicology and Environmental Safety
Disinfectant quaternary ammonium compounds (Quats) have diverse uses in a variety of consumer and commercial products, particularly cleaning products. With the emergence of the COVID-19 pandemic, they have become a primary tool to inactivate the SARS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9ed2ec3a45399229e797dfd2066e53
https://pubmed.ncbi.nlm.nih.gov/32890921
https://pubmed.ncbi.nlm.nih.gov/32890921