Zobrazeno 1 - 10
of 48
pro vyhledávání: '"FCM, flow cytometry"'
Autor:
Shijun Zhang, Zhuomao Mo, Wen Ma, Ling Yu, Zhenjie Wang, Binhua Zou, Rui Sun, Yuanyuan Yang, Zhiqiang Yu, Meng Yu
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 2004-2015 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 2004-2015 (2021)
Hepatocellular carcinoma (HCC) has been known as the second common leading cancer worldwide, as it responds poorly to both chemotherapy and medication. Triptolide (TP), a diterpenoid triepoxide, is a promising treatment agent for its effective antica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228ab8ce9785b9f5dd7b0474572f6403
http://europepmc.org/articles/PMC8343191
http://europepmc.org/articles/PMC8343191
Autor:
Rheinallt M. Jones, Bejan Saeedi, Richard U. Eboka, Trevor Darby, Joshua A. Owens, Crystal Naudin, Sarah Hunter-Chang, Maria E. Barbian, Lauren Askew, Brian S. Robinson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1311-1327 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims In colorectal cancer, approximately 95% of patients are refractory to immunotherapy because of low antitumor immune responses. Therefore, there is an exigent need to develop treatments that increase antitumor immune responses and de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a2842f4bdfc40a2fd1a616f50f932c
https://doi.org/10.1016/j.jcmgh.2021.06.001
https://doi.org/10.1016/j.jcmgh.2021.06.001
Autor:
Rui Wang, Dandan Zhong, Yiqing Qiu, Jingni Wu, Yongliang Zhu, Zhenya Song, Jingwen Liu, Hongping Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1433-1455 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Rapid gastric epithelial progenitor cell (EPC) proliferation and inflammatory response inhibition play key roles in promoting the repair of gastric mucosal damage. However, specific targets inducing these effects are unknown. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f416abd6bb2732c90ffabe02f872fe52
https://doi.org/10.1016/j.jcmgh.2021.06.020
https://doi.org/10.1016/j.jcmgh.2021.06.020
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss, Pp 101137-(2021)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Cytoskeletal proteins are essential in maintaining cell morphology, proliferation, and viability as well as internalizing molecules in phagocytic and non-phagocytic cells. Orderly aligned cytoskeletons are disturbed by a range of biological processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a8d217c5bd4f1ce52f0a2d7d85fcd6
http://www.sciencedirect.com/science/article/pii/S2405580821002314
http://www.sciencedirect.com/science/article/pii/S2405580821002314
Autor:
Juhui Chen, Junxin Wu, Lurong Zhang, Jiancheng Li, Jun Liu, Xiandong Lin, Wanzun Lin, Sufang Qiu, Jiayu Ma
Publikováno v:
EBioMedicine, Vol 49, Iss, Pp 133-144 (2019)
EBioMedicine
EBioMedicine
Background: Active immunotherapy is an effective, long-lasting, cheap and safe way to suppress the progression of cancer, however, the key issue is to find the appropriate tumor vaccines. Oncoproteins are up-regulated under various stresses, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24a04deb52f11113fb861ab77556485
http://www.sciencedirect.com/science/article/pii/S2352396419306899
http://www.sciencedirect.com/science/article/pii/S2352396419306899
Autor:
Zhigang Xu, Peng Xue, Tian Zhang, Yao Xiao, Xiaoxiao Shi, Zhi-Jun Sun, Shao-Chen Yang, Yuejun Kang, Xianbin Ma, Qi-Chao Yang, Shuo Wang, Gang Liu
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 451-466 (2022)
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 451-466 (2022)
The combination of chemotherapy and immunotherapy motivates a potent immune system by triggering immunogenic cell death (ICD), showing great potential in inhibiting tumor growth and improving the immunosuppressive tumor microenvironment (ITM). Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5211c83ba6d95f3418ded0361dee33da
https://pubmed.ncbi.nlm.nih.gov/35127398
https://pubmed.ncbi.nlm.nih.gov/35127398
Autor:
Zongming Song, Xiexie Liu, Ji-Neng Lv, Xiaoyu Liu, Junzhao Zhao, Haihua Xie, Chenchen Zhou, Yuanyuan Liu, Bang Wang, Xiubin He, Yong Liu, Xiujuan Lv, Mingchun Li, Feng Gu, Lianchao Tang, Changbao Liu
Publikováno v:
The Journal of Biological Chemistry
Clustered regularly interspaced short palindromic repeat–Cas12a has been harnessed to manipulate the human genome; however, low cleavage efficiency and stringent protospacer adjacent motif hinder the use of Cas12a-based therapy and applications. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7595f67ca5aefcb1841f84fec2c1f167
http://europepmc.org/articles/PMC7961096
http://europepmc.org/articles/PMC7961096
Autor:
Florencio C. Ballesteros, Vincenzo Belgiorno, Pietro Campiglia, Tiziano Zarra, Antonio Buonerba, Giovanni Vigliotta, Vincenzo Naddeo, Gregory V. Korshin, Mary Vermi Aizza Corpuz
Publikováno v:
The Science of the Total Environment
Science of The Total Environment
Science of The Total Environment
This paper presents an updated and comprehensive review on the different methods used for detection and quantification of viruses in wastewater treatment systems. The analysis of viability of viruses in wastewater and sludge is another thrust of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5de715260124c1c1d43266a10381b20
http://europepmc.org/articles/PMC7368910
http://europepmc.org/articles/PMC7368910
Autor:
Yasuaki Shirayoshi, Kohei Fukuoka, Kumi Morikawa, Yoshiko Suyama, Shunjiro Yagi, Kazuomi Nakamura, Kenshiro Yamamoto, Tetsuya Ohbayashi, Ichiro Hisatome
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 18, Iss, Pp-(2019)
Biochemistry and Biophysics Reports, Vol 18, Iss, Pp-(2019)
In the present study, we have established a novel transgenic mouse and transgenic rats with dual reporters of EGFP and ELuc. In these transgenic (Tg) rodents, both GFP fluorescent and luciferase luminescent signals were ubiquitously detected in the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3ff2dc0bfce64d3be01b86a85a9ef8
https://pubmed.ncbi.nlm.nih.gov/31193220
https://pubmed.ncbi.nlm.nih.gov/31193220
Autor:
Baranyi, Ulrike, Farkas, Andreas M., Hock, Karin, Mahr, Benedikt, Linhart, Birgit, Gattringer, Martina, Focke-Tejkl, Margit, Petersen, Arnd, Wrba, Fritz, Rülicke, Thomas, Valenta, Rudolf, Wekerle, Thomas
Publikováno v:
EBioMedicine
EBioMedicine, Vol 7, Iss C, Pp 230-239 (2016)
EBioMedicine, Vol 7, Iss C, Pp 230-239 (2016)
Background Therapeutic strategies for the prophylaxis of IgE-mediated allergy remain an unmet medical need. Cell therapy is an emerging approach with high potential for preventing and treating immunological diseases. We aimed to develop a cell-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1cff621a3dd57452f02889e4e632776e
http://europepmc.org/articles/PMC4909362
http://europepmc.org/articles/PMC4909362