Zobrazeno 1 - 10
of 776
pro vyhledávání: '"FC FRAGMENT"'
Autor:
Anna Zakrzewicz, Katrien Vanderheyden, Yad Galaly, Simon Feldhoff, Magdalena Sips, Maximilian Brinkhaus, Ritva Tikkanen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The neonatal Fc receptor (FcRn) is important for numerous cellular processes that involve antibody recycling and trafficking. A major function of FcRn is IgG recycling and half-life prolongation, and FcRn blockade results in a reduction of autoantibo
Externí odkaz:
https://doaj.org/article/d8db3bf2f6a64a55929016d2d491384e
Autor:
Taoping Zhang, Zhixin Chen, Lyu Xie, Ruixian Xu, Lu Chen, Ting Jia, Wengang Shi, Yongbo Wang, Yuzhu Song, Qinqin Han, Xueshan Xia, Tao Yuan, Jinyang Zhang
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Japanese encephalitis virus (JEV), a member of the Flaviviridae family and a flavivirus, is known to induce acute encephalitis. Vimentin protein has been identified as a potential receptor for JEV, engaging in interactions with the viral membrane pro
Externí odkaz:
https://doaj.org/article/c20a332ab3ca48009ab95f4b8d01c691
Publikováno v:
Zhongguo shuxue zazhi, Vol 36, Iss 2, Pp 121-125 (2023)
Objective To establish a method for determinating the antigen-dependent cell-mediated cytotoxicity (ADCC) of human immunoglobulin (pH4)for intravenous injection (IVIG) on luciferase reporter gene-modified cell assay. Methods As effector cells, Jurkat
Externí odkaz:
https://doaj.org/article/23fd35dc0a1942818abdb9ce53b8077c
Publikováno v:
Zhongguo shuxue zazhi, Vol 36, Iss 2, Pp 125-129 (2023)
Objective To investigate the effect of immunoglobulin G (IgG) dimer concentration of intravenous immunoglobulin (IVIG) on the binding ability of IgG Fc fragment to THP-1 cell surface receptors. Methods Firstly, protein purification and high performan
Externí odkaz:
https://doaj.org/article/6f95c7167e5c46658430a81c9a2a5614
Publikováno v:
Zhongguo shuxue zazhi, Vol 35, Iss 12, Pp 1199-1203 (2022)
Objective To research the effect of the Fc, Fab and F(ab′)2 fragments of immunoglobulin G, the main components of Human Immunoglobulin(pH4) for Intravenous Injection(IVIG), on the phagocytic function of macrophages derived from THP-1 cells. Methods
Externí odkaz:
https://doaj.org/article/0effad24342d41698dceccccd9e4c26b
Autor:
Yuhong Suo, Chunyu Hou, Guang Yang, Hongfeng Yuan, Lina Zhao, Yufei Wang, Ningning Zhang, Xiaodong Zhang, Wei Lu
Publikováno v:
Biomolecules & Biomedicine, Vol 23, Iss 4 (2023)
The Fc fragment of IgG binding protein (FCGBP) has been confirmed to play an important role in various cancers. However, the specific role of FCGBP in hepatocellular carcinoma (HCC) remains undefined. Thus, in this study, the enrichment analyses (Gen
Externí odkaz:
https://doaj.org/article/a0f0ceaf29d84ac6a038f196957db37e
Autor:
Xiang-Yu Liu, Mao-Hua Zhu, Xiao-Yu Wang, Xiao Dong, Hai-Jun Liu, Rui-Yang Li, Shi-Chong Jia, Qin Lu, Mei Zhao, Peng Sun, Hong-Zhuan Chen, Chao Fang
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Harnessing the immune system to fight cancer has led to prominent clinical successes. Strategies to stimulate innate immune effectors are attracting considerable interest in cancer therapy. Here, through conjugating multivalent Fc
Externí odkaz:
https://doaj.org/article/964439c5324b4c4294f327a7b9c4217b
Akademický článek
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Publikováno v:
Инфекция и иммунитет, Vol 10, Iss 1, Pp 55-63 (2020)
The pathogenesis of poststreptococcal glomerulonephritis (PSGN), a major complication of acute infections caused by group A streptococci (GAS) remains unclear. Several theories, based on the role of certain streptococcal virulence factors, as well as
Externí odkaz:
https://doaj.org/article/f2b92b17085a4617959d3c4aa4a97c91
Autor:
Céline Monnet, Emilie Jacque, Christophe de Romeuf, Alexandre Fontayne, Toufik Abache, Nathalie Fournier, Gilles Dupont, Delphine Derache, Anais Engrand, Aurélie Bauduin, Aurélie Terrier, Alexander Seifert, Cécile Beghin, Alain Longue, Nicholas Masiello, Laetitia Danino, Michel Nogre, Anais Raia, Frederic Dhainaut, Louis Fauconnier, Dieudonnée Togbe, Carmen Reitinger, Falk Nimmerjahn, Wil Stevens, Sami Chtourou, Philippe Mondon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Novel molecules that directly target the neonatal Fc receptor (FcRn) and/or Fc gamma receptors (FcγRs) are emerging as promising treatments for immunoglobulin G (IgG)-dependent autoimmune pathologies. Mutated Fc regions and monoclonal antibodies tha
Externí odkaz:
https://doaj.org/article/cb98171ccd1c4db4b09ceb279bdb5740