Soluble and pelletable factors in porcine, canine and human notochordal cell-conditioned medium: implications for IVD regeneration

Autor: FC Bach, SAH de Vries, FM Riemers, J Boere, FWM van Heel, M van Doeselaar, SS Goerdaya, PGJ Nikkels, K Benz, LB Creemers, AF Maarten Altelaar, BP Meij, K Ito, MA Tryfonidou

Publikováno v: European Cells & Materials, Vol 32, Pp 163-180 (2016)

During intervertebral disc (IVD) maturation, notochordal cells (NCs) are replaced by chondrocyte-like cells (CLCs) in the nucleus pulposus, suggesting that NCs play a role in maintaining tissue health. Affirmatively, NC-conditioned medium (NCCM) exer

Externí odkaz: https://doaj.org/article/dd49067ba6dc45d48bab91803fd316f4

Targeted screening of inflammatory mediators in spontaneous degenerative disc disease in dogs reveals an upregulation of the tumor necrosis superfamily.

Autor: Bitterli T; Clinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty University of Zurich Zurich Switzerland., Schmid D; Clinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty University of Zurich Zurich Switzerland., Ettinger L; Clinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty University of Zurich Zurich Switzerland., Krupkova O; Clinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty University of Zurich Zurich Switzerland.; Spine Surgery University Hospital Basel Basel Switzerland.; Department of Biomedicine University of Basel & University Hospital Basel, Tissue Engineering Basel Switzerland., Bach FC; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht the Netherlands., Tryfonidou MA; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht the Netherlands., Meij BP; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht the Netherlands., Pozzi A; Clinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty University of Zurich Zurich Switzerland., Steffen F; Clinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty University of Zurich Zurich Switzerland., Wuertz-Kozak K; Institute for Biomechanics, ETH Zurich Zurich Switzerland.; Department of Biomedical Engineering Rochester Institute of Technology (RIT) Rochester New York USA.; Schön Clinic Munich Harlaching, Spine Center Academic Teaching Hospital and Spine Research Institute of the Paracelsus Medical University Salzburg (Austria) Munich Germany., Smolders LA; Clinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty University of Zurich Zurich Switzerland.

Publikováno v: JOR spine [JOR Spine] 2023 Nov 23; Vol. 7 (1), pp. e1292. Date of Electronic Publication: 2023 Nov 23 (Print Publication: 2024).

Epidemiology of Modic changes in dogs: Prevalence, possible risk factors, and association with spinal phenotypes.

Autor: Beukers M; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Grinwis GCM; Department of Biomolecular Health Sciences, Pathology Division, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Vernooij JCM; Department of Population Health Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., van der Hoek L; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Tellegen AR; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Meij BP; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Veraa S; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Samartzis D; Department of Orthopaedic Surgery, Rush Medical College Rush University Medical Center Chicago Illinois USA., Tryfonidou MA; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Bach FC; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands.

Publikováno v: JOR spine [JOR Spine] 2023 Jul 21; Vol. 6 (3), pp. e1273. Date of Electronic Publication: 2023 Jul 21 (Print Publication: 2023).

Harmonization and standardization of nucleus pulposus cell extraction and culture methods.

Autor: Basatvat S; Biomolecular Sciences Research Centre Sheffield Hallam University Sheffield UK., Bach FC; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Barcellona MN; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin The University of Dublin Dublin Ireland., Binch AL; Biomolecular Sciences Research Centre Sheffield Hallam University Sheffield UK., Buckley CT; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin The University of Dublin Dublin Ireland., Bueno B; Leni & Peter W. May Department of Orthopaedics Icahn School of Medicine at Mount Sinai New York New York USA., Chahine NO; Departments of Orthopedic Surgery and Biomedical Engineering Columbia University New York New York USA., Chee A; Department of Orthopedic Surgery Rush University Medical Center Chicago Illinois USA., Creemers LB; Department of Orthopedics University Medical Center Utrecht Utrecht The Netherlands., Dudli S; Center for Experimental Rheumatology University of Zurich Zurich Switzerland., Fearing B; Department of Orthopedic Surgery Atrium Health Musculoskeletal Institute Charlotte North Carolina USA., Ferguson SJ; Institute for Biomechanics ETH Zurich Zurich Switzerland., Gansau J; Leni & Peter W. May Department of Orthopaedics Icahn School of Medicine at Mount Sinai New York New York USA., Gantenbein B; Bone & Joint Program, Department for BioMedical Research (DBMR), Medical Faculty University of Bern Bern Switzerland.; Department for Orthopedics and Traumatology, Insel University Hospital University of Bern Bern Switzerland., Gawri R; Division of Orthopaedic Surgery, Department of Surgery McGill University Montreal Canada.; Regenerative Orthopaedics and Innovation Laboratory McGill University Montreal Canada., Glaeser JD; Cedars-Sinai Medical Center Los Angeles California USA., Grad S; AO Research Institute Davos Davos Switzerland., Guerrero J; Bone & Joint Program, Department for BioMedical Research (DBMR), Medical Faculty University of Bern Bern Switzerland.; Center of Dental Medicine, Oral Biotechnology & Bioengineering University of Zurich Zurich Switzerland., Haglund L; Division of Orthopaedic Surgery, Department of Surgery McGill University Montreal Canada., Hernandez PA; Department of Orthopaedic Surgery University of Texas Southwestern Medical Center Dallas Texas USA., Hoyland JA; School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre The University of Manchester Manchester UK., Huang C; Department of Biomedical Engineering University of Miami Coral Gables Florida USA., Iatridis JC; Leni & Peter W. May Department of Orthopaedics Icahn School of Medicine at Mount Sinai New York New York USA., Illien-Junger S; Department of Orthopaedics Emory University School of Medicine Atlanta GA USA., Jing L; Department of Orthopaedics Emory University School of Medicine Atlanta GA USA.; Department of Biomedical Engineering Washington University in St. Louis St. Louis Missouri USA., Kraus P; Department of Orthopaedics Emory University School of Medicine Atlanta GA USA.; Department of Biology Clarkson University Potsdam New York USA., Laagland LT; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Lang G; Department of Orthopedics and Trauma Surgery, Medical Center, Faculty of Medicine Albert-Ludwigs-University of Freiburg Freiburg im Breisgau Germany., Leung V; Department of Orthopaedics & Traumatology The University of Hong Kong Hong Kong SAR China., Li Z; AO Research Institute Davos Davos Switzerland., Lufkin T; Department of Biology Clarkson University Potsdam New York USA., van Maanen JC; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., McDonnell EE; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin The University of Dublin Dublin Ireland., Panebianco CJ; Leni & Peter W. May Department of Orthopaedics Icahn School of Medicine at Mount Sinai New York New York USA., Presciutti SM; Department of Orthopaedics Emory University School of Medicine Atlanta GA USA., Rao S; Leni & Peter W. May Department of Orthopaedics Icahn School of Medicine at Mount Sinai New York New York USA., Richardson SM; School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre The University of Manchester Manchester UK., Romereim S; Department of Orthopedic Surgery Atrium Health Musculoskeletal Institute Charlotte North Carolina USA., Schmitz TC; Orthopaedic Biomechanics, Department of Biomedical Engineering Eindhoven University of Technology Eindhoven The Netherlands., Schol J; Department of Orthopedic Surgery Tokai University School of Medicine Isehara Japan., Setton L; Departments of Biomedical Engineering and Orthopedic Surgery Washington University in St. Louis St. Louis Missouri USA., Sheyn D; Cedars-Sinai Medical Center Los Angeles California USA., Snuggs JW; Biomolecular Sciences Research Centre Sheffield Hallam University Sheffield UK., Sun Y; Department of Orthopaedics & Traumatology The University of Hong Kong Hong Kong SAR China., Tan X; Department of Biomedical Engineering Washington University in St. Louis St. Louis Missouri USA., Tryfonidou MA; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Vo N; Department of Orthopaedic Surgery University of Pittsburgh Pittsburgh Pennsylvania USA., Wang D; Department of Orthopaedic Surgery University of Pittsburgh Pittsburgh Pennsylvania USA., Williams B; Department of Orthopedic Surgery Rush University Medical Center Chicago Illinois USA., Williams R; Biomolecular Sciences Research Centre Sheffield Hallam University Sheffield UK., Yoon ST; Department of Orthopaedics Emory University School of Medicine Atlanta GA USA., Le Maitre CL; Biomolecular Sciences Research Centre Sheffield Hallam University Sheffield UK.; Department of Oncology and Metabolism University of Sheffield Sheffield South Yorkshire UK.

Publikováno v: JOR spine [JOR Spine] 2023 Jan 10; Vol. 6 (1), pp. e1238. Date of Electronic Publication: 2023 Jan 10 (Print Publication: 2023).

Hyperosmolar expansion medium improves nucleus pulposus cell phenotype.

Autor: Laagland LT; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Bach FC; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Creemers LB; Department of Orthopedics University Medical Centre Utrecht Utrecht The Netherlands., Le Maitre CL; Biomolecular Sciences Research Centre Sheffield Hallam University Sheffield UK., Poramba-Liyanage DW; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands., Tryfonidou MA; Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands.

Publikováno v: JOR spine [JOR Spine] 2022 Aug 18; Vol. 5 (3), pp. e1219. Date of Electronic Publication: 2022 Aug 18 (Print Publication: 2022).