Zobrazeno 1 - 10
of 4 076
pro vyhledávání: '"FAp"'
Autor:
Xiang Zhao, Jieming Lin, Mingyang Liu, Dongxin Jiang, Yu Zhang, Xin Li, Bo Shi, Jun Jiang, Chunhui Ma, Hongda Shao, Qingrong Xu, Huang Ping, Jiajin Li, Yanzheng Gao
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Osteoarthritis (OA) is a common joint disease that leads to chronic pain and functional limitations. Recent research has revealed soluble fibroblast activation protein (FAP) secreted from OA synovium could degrade type II collagen
Externí odkaz:
https://doaj.org/article/97193c2a411b496bbb45e0b772781f27
Autor:
Shaoyu Liu, Ziqi Zhang, Jiawei Zhong, Huizhen Zhong, Yimin Fu, Lifang Liu, Xiaoting Ye, Xinlu Wang
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background Fibroblast activation protein (FAP) has gained attention as a promising molecular target with potential utility for cancer diagnosis and therapy. [68Ga]Ga-labeled FAP-targeting peptides have been successfully applied to positron e
Externí odkaz:
https://doaj.org/article/0e8c3cda9bac4f9996e99d54f6b91124
Publikováno v:
Journal of Biomedical Physics and Engineering, Vol 14, Iss 4, Pp 323-334 (2024)
Background: Fibroblast Activation Protein (FAP)-targeted nanoparticles (NPs) are designed to accumulate in cancerous stroma. These NPs hold promise for imaging applications in cancer therapy.Objective: This systematic review aimed to comprehensively
Externí odkaz:
https://doaj.org/article/0f5e5a27b03a4754bf14c8a87883abc5
Autor:
Circe D. van der Heide, Hanyue Ma, Mark W.H. Hoorens, Joana D. Campeiro, Debra C. Stuurman, Corrina M.A. de Ridder, Yann Seimbille, Simone U. Dalm
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Background Fibroblast activation protein (FAP), a transmembrane serine protease overexpressed by cancer-associated fibroblasts in the tumor stroma, is an interesting biomarker for targeted radionuclide theranostics. FAP-targeting radiotracer
Externí odkaz:
https://doaj.org/article/faeb0767207f487993563351427f99e8
Autor:
Fatemeh Eskandari-Malayeri, Marzieh Rezeai, Tahmineh Narimani, Nafiseh Esmaeil, Mahdieh Azizi
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Fusobacterium nucleatum, (F. nucleatum) as a known factor in inducing oncogenic, invasive, and inflammatory responses, can lead to an increase in the incidence and progression of colorectal cancer (CRC). Cancer-associated fibroblasts (CAF) a
Externí odkaz:
https://doaj.org/article/ef2d5702d4994ac7be5ae293fa34bde1
Autor:
Laura C. Jorgenson, Michael S. Torbenson, Thorvardur R. Halfdanarson, Lionel A. Kankeu Fonkoua, Nguyen H. Tran, Lewis R. Roberts, Rory L. Smoot, Ajit H. Goenka, Scott M. Thompson
Publikováno v:
Frontiers in Nuclear Medicine, Vol 4 (2024)
PurposeThe aims of this study were to evaluate and compare fibroblast activation protein (FAP) expression and localization in surgically resected cholangiocarcinoma (CCA), primary and metastatic hepatocellular carcinoma (HCC), hepatocellular adenoma
Externí odkaz:
https://doaj.org/article/3d65c3d15d544dd99b73fb6b89d3c9b6
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Idiopathic pulmonary fibrosis (IPF) is a rare, chronic, and progressive interstitial lung disease with an average survival of approximately 3 years. The evolution of IPF is unpredictable, with some patients presenting a relatively stable condition wi
Externí odkaz:
https://doaj.org/article/df53b352b50f4deeb1d636d397de5df4
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/3a59cca7053246dd8093beb714c1db17
Publikováno v:
Journal of Isotopes, Vol 38, Iss 2, Pp 106-125 (2024)
Abstract: Fibroblast activation protein (FAP) exists in tumor stromal fibroblasts and is a significant target for tumor diagnosis and treatment recently. Among the radioactive FAP-targeted tumor imaging agents, small-molecule tracers have received th
Externí odkaz:
https://doaj.org/article/24a036854a3b42cb934466ab078ab6d3
Autor:
Yan Zhao, Yunlong Jia, Jiali Wang, Xiaolin Chen, Jingya Han, Shuman Zhen, Shuxian Yin, Wei Lv, Fan Yu, Jiaqi Wang, Fan Xu, Xinming Zhao, Lihua Liu
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-20 (2024)
Abstract Background Cancer-associated fibroblasts (CAFs) orchestrate a supportive niche that fuels cancer metastatic development in non-small cell lung cancer (NSCLC). Due to the heterogeneity and plasticity of CAFs, manipulating the activated phenot
Externí odkaz:
https://doaj.org/article/51cf8744b8f44dd88cd61cc209c5c8cb