Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei

Autor: Christopher J. McLean, Jon Marles-Wright, Rafael Custodio, Jonathan Lowther, Amanda J. Kennedy, Jacob Pollock, David J. Clarke, Alan R. Brown, Dominic J. Campopiano

Publikováno v: Journal of Lipid Research, Vol 58, Iss 1, Pp 137-150 (2017)

Sphingolipids (SLs) are ubiquitous elements in eukaryotic membranes and are also found in some bacterial and viral species. As well as playing an integral structural role, SLs also act as potent signaling molecules involved in numerous cellular pathw

Externí odkaz: https://doaj.org/article/b88abd542b6b4e52bfb50f3531326388

An enzymatic tandem reaction to produce odor-active fatty aldehydes

Autor: Jean-Philippe Kanter, Philipp Jakob Honold, David Lüke, Sven Heiles, Bernhard Spengler, Marco Alexander Fraatz, Christoph Harms, Jakob Peter Ley, Holger Zorn, Andreas Klaus Hammer

Publikováno v: Applied microbiology and biotechnology. 106(18)

Abstract Aldehydes represent a versatile and favored class of flavoring substances. A biocatalytic access to odor-active aldehydes was developed by conversion of fatty acids with two enzymes of the α-dioxygenase pathway. The recombinant enzymes α-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4da7fce87fd4c0c8ae4d1ed4be6646
https://pubmed.ncbi.nlm.nih.gov/36040487

Disturbed brain ether lipid metabolism and histology in Sjögren-Larsson syndrome

Autor: Martin Lammens, Gert Van Goethem, Michèl A.A.P. Willemsen, Bram Heijs, Marjolein Breur, Martin Giera, Mia L. Pras-Raves, Pippa Staps, Marianna Bugiani, Ron A. Wevers, Marinette van der Graaf, Annemieke Groen, William B. Rizzo, Frédéric M. Vaz, Antoine H. C. van Kampen, Sacha Ferdinandusse

Publikováno v: Journal of Inherited Metabolic Disease
Staps, P, Rizzo, W B, Vaz, F M, Bugiani, M, Giera, M, Heijs, B, van Kampen, A H C, Pras-Raves, M L, Breur, M, Groen, A, Ferdinandusse, S, van der Graaf, M, Van Goethem, G, Lammens, M, Wevers, R A & Willemsen, M A A P 2020, ' Disturbed brain ether lipid metabolism and histology in Sjögren-Larsson syndrome ', Journal of Inherited Metabolic Disease, vol. 43, no. 6, pp. 1265-1278 . https://doi.org/10.1002/jimd.12275
Journal of inherited metabolic disease
Journal of Inherited Metabolic Disease, 43(6), 1265-1278. Springer Netherlands
Journal of Inherited Metabolic Disease, 43(6), 1265-1278. WILEY
Journal of Inherited Metabolic Disease, 43, 6, pp. 1265-1278
Journal of Inherited Metabolic Disease, 43, 1265-1278
Journal of inherited metabolic disease, 43(6), 1265-1278. Springer Netherlands

Contains fulltext : 229584.pdf (Publisher’s version ) (Open Access) Sjögren-Larsson syndrome (SLS) is a rare neurometabolic syndrome caused by deficient fatty aldehyde dehydrogenase. Patients exhibit intellectual disability, spastic paraplegia, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781e1d007f55fc9568293faf0b68d494
http://www.scopus.com/inward/record.url?scp=85087697934&partnerID=8YFLogxK

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Metabolism of phytol to phytanic acid in the mouse, and the role of PPARα in its regulation

Autor: J. Gloerich, D.M. van den Brink, J. P.N. Ruiter, N. van Vlies, F.M. Vaz, R. J.A. Wanders, S. Ferdinandusse

Publikováno v: Journal of Lipid Research, Vol 48, Iss 1, Pp 77-85 (2007)

Phytol, a branched-chain fatty alcohol, is the naturally occurring precursor of phytanic and pristanic acid, branched-chain fatty acids that are both ligands for the nuclear hormone receptor peroxisome proliferator-activated receptor α (PPARα). To

Externí odkaz: https://doaj.org/article/b815119721f64338b249701cc076ea95