FAT1: a potential target for monoclonal antibody therapy in colon cancer

Autor: Luigi Terracciano, Alberto Grandi, Matteo Parri, Ilaria Naldi, Guido Grandi, Chaojun Song, Elisa De Camilli, Susanna Campagnoli, Boquan Jin, Renata Grifantini, Caterina Cinti, Luisa Ganfini, Giuseppe Viale, Piero Pileri, Aurelien Lacombe, Paolo Sarmientos

Publikováno v: British Journal of Cancer 114 (2016): 40–51. doi:10.1038/bjc.2016.145
info:cnr-pdr/source/autori:Piero Pileri, Susanna Campagnoli, Alberto Grandi, Matteo Parri, Elisa De Camilli, Chaojun Song, Luisa Ganfini, Aurelien Lacombe, Ilaria Naldi, Paolo Sarmientos, Caterina Cinti, Boquan Jin, Guido Grandi, Giuseppe Viale, Luigi Terracciano and Renata Grifantini/titolo:FAT1: a potential target for monoclonal antibody therapy in colon cancer/doi:10.1038%2Fbjc.2016.145/rivista:British Journal of Cancer/anno:2016/pagina_da:40/pagina_a:51/intervallo_pagine:40–51/volume:114
British Journal of Cancer

Background: Colorectal cancer (CRC) is one of the major causes of cancer-associated mortality worldwide. The currently approved therapeutic agents have limited efficacy. Methods: The atypical cadherin FAT1 was discovered as a novel CRC-associated pro

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