Zobrazeno 1 - 10
of 1 225
pro vyhledávání: '"FASN"'
Autor:
Miguel A. Diaz, Felisa Vázquez-Gómez, Irene Garrido, Francisco Arias, Julia Suarez, Ismael Buño, Álvaro Lassaletta
Publikováno v:
Current Oncology, Vol 31, Iss 11, Pp 7308-7318 (2024)
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, with a median overall survival (OS) of 15–18 months despite standard treatments. Approximately 8% of GBM cases exhibit genomic alterations in fibroblast growth factor re
Externí odkaz:
https://doaj.org/article/4975a9abcb9e42969adae2f227cc5828
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Intrahepatic lipid accumulation (IHL), a hallmark of metabolic disorders, is closely associated with de novo lipogenesis (DNL). Notably, fructose feeding increased the DNL. Lifestyle modifications resulting from dietary changes an
Externí odkaz:
https://doaj.org/article/0b7b5284fc514c16b1f331125e192a1e
Autor:
Huanxian Cui, Yongli Wang, Yuting Zhu, Xiaojing Liu, Lu Liu, Jie Wang, Xiaodong Tan, Yidong Wang, Siyuan Xing, Na Luo, Li Liu, Ranran Liu, Maiqing Zheng, Guiping Zhao, Jie Wen
Publikováno v:
Journal of Advanced Research, Vol 65, Iss , Pp 19-31 (2024)
Introduction: The proportion of animal based foods in daily diet of consumers is constantly increasing, with chicken being highly favored due to its high protein and low fat characteristics. The consumption of chicken around the world is steadily inc
Externí odkaz:
https://doaj.org/article/51f4a3f37da9413e86e4aaa20e0128d9
Autor:
Ichiro Kawahara, Hirofumi Yoshino, Wataru Fukumoto, Junya Arima, Saeki Saito, Gang Li, Ikumi Fukuda, Akihiko Mitsuke, Takashi Sakaguchi, Satoru Inoguchi, Ryosuke Matsushita, Masayuki Nakagawa, Shuichi Tatarano, Yasutoshi Yamada, Hideki Enokida
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2196-2211 (2024)
Gemcitabine plus cisplatin (GC) combination chemotherapy is the primary treatment for advanced bladder cancer (BC) with unresectable or metastatic disease. However, most cases develop resistance to this therapy. We investigated whether drug resistanc
Externí odkaz:
https://doaj.org/article/c2d8257116da49f8983df134c431822c
Autor:
Mohammad Javad Fattahi, Fatemeh Sedaghat, Mohammad Reza Haghshenas, Ali Ariafar, Zahra Shiravani, Mahyar Malekzadeh, Shima Madani
Publikováno v:
Caspian Journal of Internal Medicine, Vol 15, Iss 4, Pp 636-643 (2024)
Background: Bladder cancer is one of the most common cancers in the world and is associated with high treatment costs and mortality. The role of different enzymes and molecules in this cancer has been the subject of extensive research in recent years
Externí odkaz:
https://doaj.org/article/258401be52294d49b2cb71a87b4882bb
Autor:
Chiara Papulino, Ugo Chianese, Ahmad Ali, Gregorio Favale, Concetta Tuccillo, Fortunato Ciardiello, Annabella Di Mauro, Chiara Mignogna, Gerardo Ferrara, Alfredo Budillon, Wouter Leonard Megchelenbrink, Nunzio Del Gaudio, Mariarosaria Conte, Fabrizio Merciai, Pietro Campiglia, Lucia Altucci, Vincenzo Carafa, Eduardo Sommella, Rosaria Benedetti
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Breast cancer manifests as a heterogeneous pathology marked by complex metabolic reprogramming essential to satisfy its energy demands. Oncogenic signals boost the metabolism, modifying fatty acid synthesis and glucose use from th
Externí odkaz:
https://doaj.org/article/e1c9da9a03da4c08b5e34b1d243a2230
Publikováno v:
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, Vol 32, Iss 2, Pp 44-54 (2024)
Introduction: Consuming a high-fat diet causes obesity, which is one of the hallmarks of metabolic syndrome. The present study aimed to assess the effect of aerobic training and capsaicin supplementation on the expression of lipogenic genes SREBP-1c
Externí odkaz:
https://doaj.org/article/2c6efde0d9b54b449bc3c1d13352585c
Autor:
Qiuhong Xiong, Huimin Sun, Yanlin Wang, Qian Xu, Yu Zhang, Mei Xu, Zhonghua Zhao, Ping Li, Changxin Wu
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background β-Propeller protein-associated neurodegeneration (BPAN) is a genetic neurodegenerative disease caused by mutations in WDR45. The impairment of autophagy caused by WDR45 deficiency contributes to the pathogenesis of BPAN; however,
Externí odkaz:
https://doaj.org/article/f43fecb182874029af7c8e9dd2b43d79
Publikováno v:
Heliyon, Vol 10, Iss 23, Pp e40388- (2024)
Circadian disruption is a risk factor for Parkinson's disease (PD). Ferroptosis, a cellular death process, assumes a pivotal role in the degeneration of dopaminergic neurons in PD. Despite its significance, the potential contribution of circadian clo
Externí odkaz:
https://doaj.org/article/228e266030734704a3b0923de8e3e9e9
Autor:
Jasmeet Kaur, Farheen Azad, Anish Murtaja Alam Khan, Mohd. Farzaan, Javed Ahmad, Humaira Farooqi, Kailash Chandra, Bibhu Prasad Panda
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 13, Iss , Pp 100540- (2024)
Introduction: Lentinula edodes (shiitake mushroom) has been integral to Traditional Chinese Medicine (TCM) for centuries, with its cultivation dating back to the Song dynasty (960–1127) in China. Traditionally valued for its immune-boosting propert
Externí odkaz:
https://doaj.org/article/deb61040a501424b92298b7cf8cfc882