Zobrazeno 1 - 10
of 901
pro vyhledávání: '"FAPI"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background [18F]Fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) is recommended during diagnostic work-up for ovarian cancer; however, [18F]FDG PET has several inherent limitations. The novel oncologic PET-tracer fibroblast a
Externí odkaz:
https://doaj.org/article/0aad819bc5d74f2194d1e07a5d1c070d
Autor:
Youcai Li, Yin Zhang, Zhihua Guo, Peng Hou, Jie Lv, Miao Ke, Shaoyu Liu, Siwen Li, Weiqiang Yin, Jianxing He, Xinlu Wang
Publikováno v:
Cancer Imaging, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background This study investigates the value of fluorine 18 ([18F])-labeled fibroblast activation protein inhibitor (FAPI) for lymph node (LN) metastases in patients with stage I-IIIA non-small cell lung cancer (NSCLC). Methods From November
Externí odkaz:
https://doaj.org/article/92905510e9cf48b6a6cd2b571846e600
Autor:
Yaxin Tian, Yanghongyan Jiang, Ping Ma, Xiaowei Ma, Liang Du, Fengkui Wang, Xiaodong Yu, Qian Zhao
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/8f62c0dbd7b6403a9ea613153f9f75b0
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Idiopathic pulmonary fibrosis (IPF) is a rare, chronic, and progressive interstitial lung disease with an average survival of approximately 3 years. The evolution of IPF is unpredictable, with some patients presenting a relatively stable condition wi
Externí odkaz:
https://doaj.org/article/df53b352b50f4deeb1d636d397de5df4
Autor:
Yaxin Tian, Yanghongyan Jiang, Ping Ma, Xiaowei Ma, Liang Du, Fengkui Wang, Xiaodong Yu, Qian Zhao
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeFibroblast activation protein (FAP) is highly expressed in the mesenchyme of most malignant epithelial tumors, while its expression is low in normal tissues. FAP inhibitors (FAPIs) bind specifically to FAP and are used for tumor-targeted diagn
Externí odkaz:
https://doaj.org/article/2f7f00069bdf40e3946e8860c6122f7c
Publikováno v:
Journal of Isotopes, Vol 38, Iss 2, Pp 97-105 (2024)
Abstract: Using N-(4-quinolinoyl)-Gly-(2-cyanopyrrolidine) as scaffold, we prolonged the linker with serine to obtain a FAPI derivative ATE-FAPI-03, which was subsequently labeled with 131I by electrophilic substitution. Then the in vitro stability,
Externí odkaz:
https://doaj.org/article/a0f8aa90d4544681ac0ccbcbb8fc3c17
Autor:
K. Arun Prashanth, Deepti Jain, R. Manikandan, Suman Kalyan, Vimalraj Velayutham, R. Surendran
Publikováno v:
European Journal of Hybrid Imaging, Vol 7, Iss 1, Pp 1-5 (2023)
Abstract A 60-year-old male patient diagnosed with mucinous adenocarcinoma of lower third of rectum underwent abdominoperineal resection and permanent colostomy followed by adjuvant chemotherapy. Response evaluation with F-18 FDG PET-CT showed a comp
Externí odkaz:
https://doaj.org/article/1133e06dcfb34b16a66dfd36d1c2d17d
Autor:
Louis-Paul Paty, Simon Degueldre, Claire Provost, Camille Schmitt, Laura Trump, Julien Fouque, Charles Vriamont, Frank Valla, Thibault Gendron, Olivier Madar
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Gallium-68-labeled FAPI-46 has recently been proposed as a novel positron emission tomography imaging probe to diagnose and monitor a wide variety of cancers. Promising results from several ongoing clinical trials have led to a soaring demand for thi
Externí odkaz:
https://doaj.org/article/e54e64c2c2784532a2ce2cdada441247
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeThis study aimed to investigate the characteristics of various pulmonary lesions as revealed by 68Ga-FAPI PET/CT and to determine the utility of 68Ga-FAPI PET/CT in distinguishing the nature of these pulmonary lesions.MethodsA retrospective an
Externí odkaz:
https://doaj.org/article/270640eb6380405b864c4a1805c76fcb
Publikováno v:
iRADIOLOGY, Vol 1, Iss 4, Pp 340-361 (2023)
Abstract Quinoline‐based fibroblast activation protein (FAP) inhibitor (FAPI)‐based positron emission tomography (PET) imaging and radioligand therapy (RLT) are being investigated for use in a wide variety of diseases, and recent results have bee
Externí odkaz:
https://doaj.org/article/a5f4e1478f444baa892c6d1c975ea7a5