Zobrazeno 1 - 10
of 116
pro vyhledávání: '"FANIA SZLAM"'
Autor:
Nicklaus T Rice, Fania Szlam, Jeffrey D Varner, Peter S Bernstein, Arthur D Szlam, Kenichi A Tanaka
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154127 (2016)
BACKGROUND:Thrombin generation (TG) is a pivotal process in achieving hemostasis. Coagulation profiles during pregnancy and early neonatal period are different from that of normal (non-pregnant) adults. In this ex vivo study, the differences in TG in
Externí odkaz:
https://doaj.org/article/c9f837031dca48cfa2152c958921c897
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:2909-2920
Thrombogenicity is a known complication of COVID-19, resulting from SARS-CoV-2 infection, with significant effects on morbidity and mortality.We aimed to better understand the effects of COVID-19 on fibrinogen and the resulting effects on clot struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b56a5605479063d4b4cd8dd015609d
https://doi.org/10.1111/jth.15882
https://doi.org/10.1111/jth.15882
Autor:
Fania Szlam, Christopher W. Coyle, Ernest T. Parker, Gabriela Denning, Roman M. Sniecinski, Eric A. Gaucher, Christopher B. Doering, H. Trent Spencer, Chen Michelle H, Jordan M. Shields, Kristopher A. Knight, Anatolii Purchel, Andrew Fedanov, Caelan E. Radford, Pete Lollar
Publikováno v:
Blood Adv
Orthologous proteins contain sequence disparity guided by natural selection. In certain cases, species-specific protein functionality predicts pharmacological enhancement, such as greater specific activity or stability. However, immunological barrier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6bfce55878e87a2640a3d2cba6be06c
https://doi.org/10.1182/bloodadvances.2021004742
https://doi.org/10.1182/bloodadvances.2021004742
Autor:
Yuxin Duan, Fania Szlam, Yuesong Hu, Wenchun Chen, Renhao Li, Yonggang Ke, Roman Sniecinski, Khalid Salaita
Cells transmit piconewton forces to mediate essential biological processes such as coagulation. One challenge is that cell-generated forces are infrequent, transient, and difficult to detect. Here, we report the development of Mechano-Cas12a Assisted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b7a3a64b0a4d89702ded8bccfd9fa41
https://doi.org/10.1101/2022.10.26.513907
https://doi.org/10.1101/2022.10.26.513907
Publikováno v:
Journal of Thrombosis and Thrombolysis
Patients critically ill with COVID-19 are at risk for thrombotic events despite prophylactic anticoagulation. Impaired fibrinolysis has been proposed as an underlying mechanism. Our objective was to determine if fibrinolysis stimulated by tissue plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fed8ed45a57253bff8216a572069aba
http://europepmc.org/articles/PMC8026096
http://europepmc.org/articles/PMC8026096
Publikováno v:
Journal of Clinical Anesthesia. 58:39-43
Study objective We investigated the coagulation changes that might occur in acute normovolemic hemodilution (ANH) blood over several hours during cardiac surgery requiring cardiopulmonary bypass. Design This study was a prospective observational stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fe4c9366e53a376de42ed10bf0ae10
https://doi.org/10.1016/j.jclinane.2019.04.032
https://doi.org/10.1016/j.jclinane.2019.04.032
Autor:
Fania Szlam, Ali Danesh, Jerrold H. Levy, Roman M. Sniecinski, Marie E. Steiner, Gayatri Ranganathan, Philip C. Spinella, Allan Doctor, Philip J. Norris, Mars Stone, Sheila M. Keating, Felicia L. Trachtenberg, Heather C. Inglis, Susan F. Assmann, John W. Heitman
Publikováno v:
Transfusion. 59:1209-1222
Background Retrospective studies suggested that storage age of RBCs is associated with inflammation and thromboembolism. The Red Cell Storage Duration Study (RECESS) trial randomized subjects undergoing complex cardiac surgery to receive RBCs stored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd52f63a7d876f0a0c50a84828cb917
https://doi.org/10.1111/trf.15228
https://doi.org/10.1111/trf.15228
Publikováno v:
Anesthesia and analgesia. 130(4)
BACKGROUND Coagulopathy and hemostatic abnormalities remain a challenge in patients following trauma and major surgery. Coagulopathy in this setting has a multifactorial nature due to tissue injury, hemodilution, hypothermia, and acidosis, the severi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777a89eefc5b3680e99d8eb47341f61d
https://pubmed.ncbi.nlm.nih.gov/31609256
https://pubmed.ncbi.nlm.nih.gov/31609256
Publikováno v:
Anesthesia & Analgesia. 123:535-546
BACKGROUND:The use of prothrombin complex concentrates in trauma- and surgery-induced coagulopathy is complicated by the possibility of thromboembolic events. To explore the effects of these agents on thrombin generation (TG), we investigated combina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1006ddd40f10a757fd2c5112315f24d
https://doi.org/10.1213/ane.0000000000001361
https://doi.org/10.1213/ane.0000000000001361
Autor:
Kenichi A. Tanaka, Janet D. Fernandez, Fania Szlam, Sarah W. Franklin, Nina A. Guzzetta, Traci Leong
Publikováno v:
Anesthesia & Analgesia. 122:935-942
Bleeding is a serious complication after pediatric cardiopulmonary bypass (CPB) that is associated with an increase in perioperative morbidity and mortality. Four-factor prothrombin complex concentrates (4F-PCCs) have been used off-label to supplemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e6997a5d6299f3911bc28238dc4883
https://doi.org/10.1213/ane.0000000000001098
https://doi.org/10.1213/ane.0000000000001098