Zobrazeno 1 - 10 of 20 pro vyhledávání: '"FAIHAA AHMED"'
1
Akademický článek
Meprin β expression modulates the interleukin‐6 mediated JAK2‐STAT3 signaling pathway in ischemia/reperfusion‐induced kidney injury
Autor: Shaymaa Abousaad, Faihaa Ahmed, Ayman Abouzeid, Elimelda Moige Ongeri
Publikováno v: Physiological Reports, Vol 10, Iss 18, Pp n/a-n/a (2022)
Abstract Meprin metalloproteinases have been implicated in the pathophysiology of ischemia/reperfusion (IR)‐induced kidney injury. Previous in vitro data showed that meprin β proteolytically processes interleukin‐6 (IL‐6) resulting in its inac
Externí odkaz: https://doaj.org/article/9a7ed1b479d44b3a83c334a77731ed95
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2
Akademický článek
Meprin β metalloproteases associated with differential metabolite profiles in the plasma and urine of mice with type 1 diabetes and diabetic nephropathy
Autor: Jessica Gooding, Lei Cao, Courtney Whitaker, Jean-Marie Mwiza, Mizpha Fernander, Faihaa Ahmed, Zach Acuff, Susan McRitchie, Susan Sumner, Elimelda Moige Ongeri
Publikováno v: BMC Nephrology, Vol 20, Iss 1, Pp 1-18 (2019)
Abstract Background Meprin metalloproteases are abundantly expressed in the brush border membranes of kidney proximal tubules and small intestines. Meprins are also expressed in podocytes and leukocytes (monocytes and macrophages). Meprins are implic
Externí odkaz: https://doaj.org/article/532c8128eae745d486d4c4df41ccc9b8
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4
Akademický článek
Meprin Metalloprotease Deficiency Associated with Higher Mortality Rates and More Severe Diabetic Kidney Injury in Mice with STZ-Induced Type 1 Diabetes
Autor: John E. Bylander, Faihaa Ahmed, Sabena M. Conley, Jean-Marie Mwiza, Elimelda Moige Ongeri
Publikováno v: Journal of Diabetes Research, Vol 2017 (2017)
Meprins are membrane-bound and secreted metalloproteinases consisting of α and/or β subunits that are highly expressed in kidney epithelial cells and are differentially expressed in podocytes and leukocytes (macrophages and monocytes). Several stud
Externí odkaz: https://doaj.org/article/d3dc75f0b2b14e329b72113c6e19445f
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5
PKA Cβ: a forgotten catalytic subunit of cAMP-dependent protein kinase opens new windows for PKA signaling and disease pathologies
Autor: Bjørn Steen Skålhegg, Susan S. Taylor, Lily Vu, Maximilian Wallbott, Jian Wu, Jessica G.H. Bruystens, Friedrich W. Herberg, Erik M F Machal, Blaine Baker, Kristoffer Søberg, Elimelda Moige Ongeri, Francesco Raimondi, Faihaa Ahmed
Publikováno v: Biochemical Journal. 478:2101-2119
3′,5′-cyclic adenosine monophosphate (cAMP) dependent protein kinase or protein kinase A (PKA) has served as a prototype for the large family of protein kinases that are crucially important for signal transduction in eukaryotic cells. The PKA cat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaa8b0037ae445a37c267eda66d661a
https://doi.org/10.1042/bcj20200867
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