Zobrazeno 1 - 10
of 11
pro vyhledávání: '"FAHD ALMULLA"'
Autor:
Abdulmohsen Al-Terki, Mohamed Abu-Farha, Irina AlKhairi, Preethi T. Cherian, Devarajan Sriraman, Ambika Shyamsundar, Shamsha Ali, Fahd Almulla, Jaakko Tuomilehto, Jehad A. Abubaker
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Objective: Obstructive sleep apnea (OSA) is a sleep disorder caused by the complete or partial obstruction of the upper airways. The worldwide prevalence of OSA is increasing due to its close association with obesity epidemic and multiple health comp
Externí odkaz:
https://doaj.org/article/0db38d9af72c43448d99645642087058
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145721 (2015)
Previous Studies have mapped putative loci that may probably regulate leukocyte telomere length (LTL). The strongest associations with LTL were reported for SNP rs12696304 and rs16847897 near the non-coding Ribose Nucleic Acid (RNA) molecule componen
Externí odkaz:
https://doaj.org/article/bd311d9aa6d24bc3bd140cc55fe364c4
Autor:
ASHRAF AL MADHOUN, PRASHANTHA HEBBAR, RASHEEBA NIZAM, DANIA HADDAD, MOHAMMED H. DASHTI, MOHAMED ABU-FARHA, RASHEED AHMAD, ALPHONSE T. THANGAVEL, FAHD ALMULLA
Publikováno v:
Diabetes. 71
Studies have implicated CAV1 in the pathophysiology of diabetes and obesity. Previously, we demonstrated a potential association between the CAV1 rs1997623 C/A variant and metabolic syndrome (MetS) in Kuwaiti children. In the present study, we substa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fb99c7f9e6e9fa67f5bc12602cca200
https://doi.org/10.2337/db22-1279-p
https://doi.org/10.2337/db22-1279-p
Autor:
SIHAM ABDELGANI, JOHN M. ADAMS, GIUSEPPE DANIELE, FAHD ALMULLA, RALPH A. DEFRONZO, MUHAMMAD ABDUL-GHANI, MOHAMED ABU-FARHA, STEFANO DEL PRATO
Publikováno v:
Diabetes. 71
Aim: To examine the mechanisms responsible for the increase in glucose and ketone production caused by SGLT2 inhibition with empagliflozin in T2DM patients. Research Design and Methods: 12 T2DM subjects (Age = 53; BMI = 31.7; HbA1c = 7.4%) participat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b29ab3010136778b4d03e9d3fcef9b47
https://doi.org/10.2337/db22-54-lb
https://doi.org/10.2337/db22-54-lb
Autor:
ALPHONSE T. THANGAVEL, MOHAMED ABU-FARHA, PRASHANTHA HEBBAR, MOHAMMAD G. QADDOUMI, FAHD ALMULLA, JEHAD ABUBAKER
Publikováno v:
Diabetes. 71
Background: Polypeptide N-Acetylgalactosaminyltransferase 2 (GALNT2) gene has been associated with serum lipid levels, insulin resistance, and adipogenesis. One of its variants, rs4846914 has been shown to associate with Triglycerides and HDL levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::110bd8dbf3eaf5683fd0da195eaf1018
https://doi.org/10.2337/db22-478-p
https://doi.org/10.2337/db22-478-p
Autor:
ASHRAF AL MADHOUN, DANIA HADDAD, SHIHAB P. KOCHUMON, RASHEEBA NIZAM, SINDHU JACOB, SARDAR T. SINDHU, RASHEED AHMAD, FAHD ALMULLA
Publikováno v:
Diabetes. 71
We Have previously established that caveolin-1 (CAV1) rs1997623 C/A variant is associated with metabolic syndrome in obese children (PMID: 30622557) and adults (ADA 82) . Here, we evaluated the functional role of the identified variant in association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcda06d9364c586f5b5c28dd193f0985
https://doi.org/10.2337/db22-1278-p
https://doi.org/10.2337/db22-1278-p
Autor:
MOHAMED ABU-FARHA, JEHAD ABUBAKER, IRINA AL KHAIRI, PREETHI T. CHERIAN, CHRISTINA AGYIN, SIHAM ABDELGANI, EBAA S. ALOZAIRI, JOHN M. ADAMS, FAHD ALMULLA, RALPH A. DEFRONZO, MUHAMMAD ABDUL-GHANI
Publikováno v:
Diabetes. 71
Aim: ANGPTL8 plays an important role in regulating lipoprotein lipase activity. Its plasma level is increased following nutrient ingestion. Its not well characterized whether insulin or glucose drive the increased ANGPTL8 after food uptake. To addres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e80eec719123b49fbc774dd80b0618c9
https://doi.org/10.2337/db22-211-or
https://doi.org/10.2337/db22-211-or
Autor:
FATEMA ALRASHED, FATEMAH ALZAQQAH, ASHRAF AL MADHOUN, RAWAN ALQABANDI, SARDAR T. SINDHU, FAHD ALMULLA, RASHEED AHMAD
Publikováno v:
Diabetes. 71
The onset of obesity is vastly associated with low levels of high-density lipoprotein cholesterol (HDL-C) , which predisposes to cardiovascular diseases. Recently, mounting evidence indicates that IL-6 plays a key role in metabolism, especially in li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8e4ee6eb185305db49ab74f365a21bd
https://doi.org/10.2337/db22-75-or
https://doi.org/10.2337/db22-75-or
Autor:
MOHAMMED H. DASHTI, RASHEEBA NIZAM, PRASHANTHA HEBBAR, SINDHU JACOB, SUMI E. JOHN, ARSHAD M. CHANNANATH, HESSA ALKANDARI, ALPHONSE T. THANGAVEL, FAHD ALMULLA
Publikováno v:
Diabetes. 71
There has recently been a growing interest in examining the role of epigenetic modifications, such as DNA methylation, in the etiology of type 1 diabetes (T1D) . This study aimed to delineate differences in methylation patterns between T1D-affected a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5d69b75dbe6b01574280e28c7f452f4
https://doi.org/10.2337/db22-1270-p
https://doi.org/10.2337/db22-1270-p
Autor:
ANWAR MOHAMMAD, MOHAMED ABU-FARHA, DHANYA MADHU, PREETHI T. CHERIAN, IRINA AL KHAIRI, PRASHANTHA HEBBAR, SINA A. KAVALAKATT, HOSSEIN AREFANIAN, NADA ALAM-ELDIN, ALPHONSE T. THANGAVEL, FAHD ALMULLA, JEHAD ABUBAKER
Publikováno v:
Diabetes. 71
Background: ANGPTL8 has been recently identified as lipid metabolism and inflammation regulator. It interacts with ANGPTL3 and, more recently, ANGPTL4 to regulate LPL activity. It was also shown to modulate NF-κB activity through its interaction wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b6ee30b8a8835087bbd24f5393db114
https://doi.org/10.2337/db22-1434-p
https://doi.org/10.2337/db22-1434-p