AB1186 Optimisation of rheumatology undergraduate teaching: self-directed development of powerpoint presentations based on theoretical clinical cases

Autor: RL Batten, D Coady, J Stewart, Fah Cooles

Publikováno v: Abstracts Accepted for Publication.

Background One element of rheumatology undergraduate teaching in City Hospital Sunderland, UK traditionally involves “paper cases” delivered via small group learning and discussion. Although popular it has had poor feedback from both the students

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dee3be8483290dd0e526887db01dc614
https://doi.org/10.1136/annrheumdis-2017-eular.6451

A1.13 The prevalence of a raised interferon gene signature is increased in early ra and is associated with worse disease activity

Autor: AE Anderson, Fah Cooles, Cmu Hilkens, John D. Isaacs

Publikováno v: Annals of the Rheumatic Diseases. 75:A6.1-A6

Background and Objectives An interferon gene signature (IGS) is present in 20–30% of established rheumatoid arthritis (RA) patients where it does not correlate with disease activity. However immunomodulatory treatment may mask underlying associatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c3f411d041d4fec988c912b22902e3c
https://doi.org/10.1136/annrheumdis-2016-209124.13

Role of IFN-α in Rheumatoid Arthritis.

Autor: Lin CMA; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Isaacs JD; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Cooles FAH; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK. faye.cooles@ncl.ac.uk.; Musculoskeletal Unit, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK. faye.cooles@ncl.ac.uk.

Publikováno v: Current rheumatology reports [Curr Rheumatol Rep] 2024 Feb; Vol. 26 (2), pp. 37-52. Date of Electronic Publication: 2023 Dec 05.

Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming.

Autor: Cooles FAH; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK faye.cooles@ncl.ac.uk., Tarn J; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Lendrem DW; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Naamane N; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Lin CM; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Millar B; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Maney NJ; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Anderson AE; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Thalayasingam N; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Diboll J; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Bondet V; Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France., Duffy D; Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France.; Center for Translational Research, Institut Pasteur, Paris, France., Barnes MR; Centre for Translational Bioinformatics, William Harvey Research Institute, London, UK., Smith GR; Bioinformatics Support Unit, Newcastle University Faculty of Medical Sciences, Newcastle Upon Tyne, UK., Ng S; Centre for Translational Bioinformatics, William Harvey Research Institute, London, UK., Watson D; Department of Statistical Science, University College London, London, UK., Henkin R; Centre for Translational Bioinformatics, William Harvey Research Institute, London, UK., Cope AP; Academic Department of Rheumatology, King's College London, London, UK., Reynard LN; Newcastle University Biosciences Institute, Newcastle University, Newcastle Upon Tyne, UK., Pratt AG; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK.; Musculoskeletal Research Group, The Freeman Hospital, Newcastle Upon Tyne, UK., Isaacs JD; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK.; Musculoskeletal Research Group, The Freeman Hospital, Newcastle Upon Tyne, UK.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2022 Aug 11; Vol. 81 (9), pp. 1214-1223. Date of Electronic Publication: 2022 Aug 11.

The interferon gene signature as a clinically relevant biomarker in autoimmune rheumatic disease.

Autor: Cooles FAH; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Isaacs JD; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK; Musculoskeletal Unit, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK. Electronic address: john.isaacs@ncl.ac.uk.

Publikováno v: The Lancet. Rheumatology [Lancet Rheumatol] 2022 Jan; Vol. 4 (1), pp. e61-e72. Date of Electronic Publication: 2021 Nov 17.