Zobrazeno 1 - 10
of 81
pro vyhledávání: '"F.K. Jansen"'
Autor:
P. Dousset, Xavier Dumont, Mourad Kaghad, P. Lelong, B. Pességué, David Shire, R Legoux, J.-M. Derocq, F.K. Jansen, H. Vidal, C. Carillon, B.J.P. Bourrié
Publikováno v:
Gene. 93:183-188
To assess the biological activity and pharmacokinetic properties of nonglycosylated ricin A-chain (RA), we have obtained the polypeptide following expression of a synthetic 842-bp RA gene in Escherichia coli. Expression of the gene was carried out us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3659a5a6dddaae7d767970e0c80ff850
https://doi.org/10.1016/0378-1119(90)90223-e
https://doi.org/10.1016/0378-1119(90)90223-e
Publikováno v:
International Journal of Cancer. 36:705-711
Two ricins were purified from the seeds of Ricinus communis by a simple method based on affinity chromatography allowing large-scale preparations. Separation of these 2 ricins was achieved by ion-exchange chromatography and studies of purified subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cab635c0c21789f2439f589498dd9be
https://doi.org/10.1002/ijc.2910360615
https://doi.org/10.1002/ijc.2910360615
Autor:
Hildur E. Blythman, P. Poncelet, Bernard Pau, Guy A. Voisin, J. Diaz, Gilbert Richer, F.K. Jansen, S.L. Salhi, D. Carriere, J.R. Hennequin, H. Vidal, Pierre Gros, Pierre Casellas, Francis Paolucci
Publikováno v:
Immunology Letters. 2:97-102
In an attempt to develop highly efficient antibody—drug conjugates for passive immunotherapy of cancer the A-chain of the potent toxin, ricin, was coupled to antibodies in order to render them specifically cytotoxic for target cells without the par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe6b43a286627851319521e72b4230e7
https://doi.org/10.1016/0165-2478(80)90057-7
https://doi.org/10.1016/0165-2478(80)90057-7
Publikováno v:
Journal of Immunological Methods. 81:283-297
The preparation of immunotoxins, hybrid proteins formed by disulfide bonding an antibody and the A-chain of ricin, has been studied in detail. Optimal conditions, both for the modification of the antibody and the coupling reaction between the modifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e669897a22b36dc245a0bc667fb3a88
https://doi.org/10.1016/0022-1759(85)90213-3
https://doi.org/10.1016/0022-1759(85)90213-3
Akademický článek
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Akademický článek
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Autor:
Joseph S. Lipsick, J. Mirouze, J.L Selam, J. R. Farndon, I. D. A. Johnston, Gillian M. Beattie, B Vialettes, A.Sitges Serra, PH Vague, Nathan O. Kaplan, F.K Jansen, B.K Shenton, O Thurneyssen, A G Osler
Publikováno v:
Lancet (London, England). 1(8129)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2274f2b48118d6c75170e657d5957bc
https://pubmed.ncbi.nlm.nih.gov/87744
https://pubmed.ncbi.nlm.nih.gov/87744
High Efficiency of Immunotoxin Potentiated by Lysosomotropic Amines to Specifically Kill Tumor Cells
A new class of reagents, called immunotoxins, has been synthetized, consisting of the A-ckain of ricin linked by a disulphide bridge to an antibody against defined cell surface antigens. The feasability of this approach is supported by experiments wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1feed7d604447d2d9a5151c7f701dd7d
https://doi.org/10.1016/b978-0-08-029815-3.50083-0
https://doi.org/10.1016/b978-0-08-029815-3.50083-0
Autor:
P. Poncelet, Joseph P. Brown, Ingegerd Hellström, Karl Erik Hellström, R. Roncucci, F.K. Jansen, O. Gros, H. Vidal, P. Gros, Pierre Casellas
Publikováno v:
International journal of cancer. 30(4)
Conjugates (immunotoxins) comprising ricin A-chain and monoclonal antibody 96.5, which is specific for human melanoma-associated antigen p97, inhibited protein synthesis and colony formation of cultured human melanoma cells that expressed more than 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2717dcb23864a98fa3a520617c1df9
https://pubmed.ncbi.nlm.nih.gov/7141740
https://pubmed.ncbi.nlm.nih.gov/7141740
Autor:
J. Beyer, H. Drost, Jörg Bertrams, F.A. Gries, E. Kuwert, F.K. Jansen, D. Gruneklee, H. E. Reis
Publikováno v:
Tissue antigens. 8(1)
HLA-A and B antigens were determined in 112 patient with insulin-dependent juvenile onset diabetes mellitus, who could be subdivided into “non” and “high responders” to insulin. The data revealed a trend of an association of these diabetes su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b40de2154b96327fd1a1dfb4af38792
https://pubmed.ncbi.nlm.nih.gov/960073
https://pubmed.ncbi.nlm.nih.gov/960073