Výsledky vyhledávání - "F.A.A. van Acker"

Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups

Autor: Chantal G.M Heijnen, F.A.A. van Acker, W.J.F. van der Vijgh, Guido R.M.M. Haenen, Aalt Bast

Publikováno v: Toxicology in Vitro, 15, 3-6. Elsevier Science

Toxicol In Vitro 2001 Feb;15(1):3-6 Related Articles, Books, LinkOut Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups.Heijnen CG, Haenen GR, van Acker FA, van der Vijgh WJ, Bast A.Department of Pharmacology and Toxicology, Facu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b793f309b30c5d44ec36920d83248253
https://doi.org/10.1016/s0887-2333(00)00053-9

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Chemokines: structure, receptors and functions. A new target for inflammation and asthma therapy?

Autor: H.P. Voss, F.A.A. van Acker, H. Timmerman

Publikováno v: Mediators of Inflammation, 5, 393-416. Hindawi Publishing Corporation
Mediators of Inflammation, Vol 5, Iss 6, Pp 393-416 (1996)
Mediators of Inflammation
van Acker, F A A, Voss, H P & Timmerman, H 1996, ' Chemokines: structure, receptors and functions. A new target for inflammation and asthma therapy? ', Mediators of Inflammation, vol. 5, pp. 393-416 . https://doi.org/10.1155/S0962935196000567

Five to 10% of the human population have a disorder of the respiratory tract called ‘asthma’. It has been known as a potentially dangerous disease for over 2000 years, as it was already described by Hippocrates and recognized as a disease entity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee81da8661908880025cceb32a42554
https://doi.org/10.1155/s0962935196000567

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Genotoxicity of hormonal steroids

Autor: G.J.M.J Horbach, H. F. P. Joosten, D. J. van den Dobbelsteen, E.I Krajnc, F.A.A van Acker

Publikováno v: Toxicology letters. 151(1)

Hormonal steroids have a widespread use in medicine and their side effects are continuously debated. The possible genotoxic activity of steroids has been the subject of many investigations. The natural estrogens estradiol, estrone and estriol are gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0c64c57e179737dde93082c8f3aaef
https://pubmed.ncbi.nlm.nih.gov/15177647

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New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity

Autor: Aalt Bast, J. Hulshof, Wiro M. P. B. Menge, W.J.F. van der Vijgh, Guido R.M.M. Haenen, F.A.A. van Acker

Publikováno v: Free Radical Biology and Medicine, 31, 31-37. Elsevier Science

Free Radic Biol Med 2001 Jul 1;31(1):31-7 Related Articles, Books, LinkOut New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity.van Acker FA, Hulshof JW, Haenen GR, Menge WM, van der Vijgh WJ, Bast A.Department of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11aee90050fee09e6f5dd2565c2e65d0
https://cris.maastrichtuniversity.nl/en/publications/dcd4a2b6-0739-4c0b-9cfa-fdb027c4bd66

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Acute exposure to ozone does not influence neuroreceptor density and sensitivity in guinea pig lung

Autor: H.P. Voss, H.J.M. van Hoof, F.A.A. van Acker, L. van Bree, Aalt Bast

Publikováno v: Toxicology Letters, 90, 53-60. Elsevier BV
van Hoof, H J M, van Acker, F A A, Voss, H P, van Bree, L & Bast, A 1997, ' Acute exposure to ozone does not influence neuroreceptor density and sensitivity in guinea pig lung. ', Toxicology Letters, vol. 90, pp. 53-60 . https://doi.org/10.1016/S0378-4274(96)03829-5

The effects of acute exposure of guinea pigs to 3 ppm of ozone for 2 h on the receptor density and sensitivity of the muscarinergic-, the histaminergic- and the beta-adrenergic receptor systems were studied, in order to provide more insight in the co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a4b8ed2cbeb73f3cbf423db41a797f
https://pubmed.ncbi.nlm.nih.gov/9020402

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Extension of a predictive substrate model for human cytochrome P450 2D6

Autor: F.A.A. van Acker, G. J. Bijloo, M.J. de Groot, C. Fonseca Guerra, J.G. Snijders, Nico P. E. Vermeulen

Publikováno v: de Groot, M J, Bijlo, G J, van Acker, F A A, Fonseca Guerra, C, Vermeulen, N P E & Snijders, J G 1997, ' Extension of a predictive substrate model for human cytochrome P450 2D6. ', Xenobiotica, vol. 27, pp. 357-368 . https://doi.org/10.1080/004982597240514
Xenobiotica, 27(4), 357-368
Xenobiotica, 27, 357-368. Informa Healthcare

1. Metoprolol, indoramine, codeine, tamoxifen and prodipine, compounds which are clinically used, and MDMA (ecstasy) were fitted in a small molecule model for substrates of human cytochrome P4502D6. 2. For both the R - and S -enantiomer of metoprolol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47790f8bbe8269ff2a6b6d55d033a405
https://hdl.handle.net/1871.1/575ec3a2-4ad0-479b-a2a1-d742e0e19103

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