Zobrazeno 1 - 10
of 72
pro vyhledávání: '"F.-X. Jarreau"'
Publikováno v:
Experiment. 2:253-275
Befloxatone, a novel oxazolidinone derivative, inhibited selectively and competitively monoamine oxidase (MAO)-A in human and rat brain, heart, liver and duodenum homogenates with Ki values ranging from 1.9 to 3.6 nM for MAO-A and from 270 to 900 nM
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(1)
Befloxatone, a novel oxazolidinone derivative, inhibited selectively and competitively monoamine oxidase (MAO)-A in human and rat brain, heart, liver and duodenum homogenates with Ki values ranging from 1.9 to 3.6 nM for MAO-A and from 270 to 900 nM
Autor:
D, Caille, O E, Bergis, C, Fankhauser, A, Gardes, R, Adam, T, Charieras, A, Grosset, V, Rovei, F X, Jarreau
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(1)
The pharmacological profile of befloxatone, a reversible, selective and competitive inhibitor of monoamine oxidase-A has been investigated in rodents. In mice, befloxatone was more active at potentiating generalized tremors induced by L-5-hydroxytryp
Autor:
J L, Moretti, C, Blanchot, P, Nicolas, L, Artaud, J J, Koenig, F X, Jarreau, R, Germack, G, Defer, G, Perret
Publikováno v:
Journal of nuclear biology and medicine (Turin, Italy : 1991). 38(4 Suppl 1)
3-Bromobenzyloxy phenyloxy hydroxymethyl propanol was labelled with iodine-125. Labeling yield was approximately 92%. Using HPLC and an RP18 column, Iodo*MD (MW = 412) was obtained at no-carrier-added conditions (specific activity 125 Ci/mmole). Bioc
Publikováno v:
Journal of neural transmission. Supplementum. 41
In vitro and ex-vivo studies show that befloxatone, a new oxazolidinone derivative, is a potent, reversible, competitive and specific MAO-A inhibitor (KiA from 1.9 to 3.6 nM and KiB/KiA ratio between 100 and 400, in the Rat and in Man, depending on t
Publikováno v:
Amine Oxidases: Function and Dysfunction ISBN: 9783211825211
In vitro and ex-vivo studies show that befloxatone, a new oxazolidinone derivative, is a potent, reversible, competitive and specific MAO-A inhibitor (KiA from 1.9 to 3.6 nM and KiB/KiA ratio between 100 and 400, in the Rat and in Man, depending on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a217261cc2b39f16352d08f81ffc5d0
https://doi.org/10.1007/978-3-7091-9324-2_45
https://doi.org/10.1007/978-3-7091-9324-2_45
Autor:
J, Wouters, F, Moureau, D P, Vercauteren, G, Evrard, F, Durant, J J, Koenig, F, Ducrey, F X, Jarreau
Publikováno v:
Journal of neural transmission. Supplementum. 41
Experimental and theoretical physico-chemical methods were used to investigate the interaction between aryl-oxazolidinones and monoamine oxidase (MAO). Several arguments suggest that these compounds interact with the flavin adenine dinucleotide (FAD)
Publikováno v:
Amine Oxidases: Function and Dysfunction ISBN: 9783211825211
Single administration of befloxatone (0.75 mg/kg, i.p.) in the rat increased extracellular levels of DA (+300%) in striatum. In frontal cortex, befloxatone (0.75 mg/kg, i.p.) and nialamide (100 mg/kg, i.p.) increased NA by +100% but did not modify 5H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::170c95d3cffa73b3960c4cdd134a8f15
https://doi.org/10.1007/978-3-7091-9324-2_46
https://doi.org/10.1007/978-3-7091-9324-2_46
Publikováno v:
Journal of neural transmission. Supplementum. 41
Single administration of befloxatone (0.75 mg/kg, i.p.) in the rat increased extracellular levels of DA (+300%) in striatum. In frontal cortex, befloxatone (0.75 mg/kg, i.p.) and nialamide (100 mg/kg, i.p.) increased NA by +100% but did not modify 5H
Autor:
J. Wouters, F. Moureau, M. Dory, G. Evrard, J. J. Koenig, F. Ducrey, F. X. Jarreau, F. Durant
Publikováno v:
Trends in QSAR and Molecular Modelling 92 ISBN: 9789072199133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50ca4d9aef3926ba913803a355a23d9b
https://doi.org/10.1007/978-94-011-1472-1_50
https://doi.org/10.1007/978-94-011-1472-1_50