Pb(II) Induces Scramblase Activation and Ceramide-Domain Generation in Red Blood Cells

Autor: Hasna Ahyayauch, Aritz B. García-Arribas, Jesús Sot, Emilio J. González-Ramírez, Jon V. Busto, Bingen G. Monasterio, Noemi Jiménez-Rojo, F. Xabier Contreras, Adela Rendón-Ramírez, Cesar Martin, Alicia Alonso, Félix M. Goñi

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)

Abstract The mechanisms of Pb(II) toxicity have been studied in human red blood cells using confocal microscopy, immunolabeling, fluorescence-activated cell sorting and atomic force microscopy. The process follows a sequence of events, starting with

Externí odkaz: https://doaj.org/article/37d7248c8b5a44c8b4b2d7778320e8bc

Membrane Nanodomains

Autor: Félix M Goñi, Alicia Alonso, F Xabier Contreras

Publikováno v: eLS. :1-8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5884bffdf16f536a0a01256ead2b5cdb
https://doi.org/10.1002/9780470015902.a0028879

Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA

Autor: Edgar D. Páez-Pérez, Lei Wang, Itxaso Anso, Christian Jäger, Martine Gilleron, Beatriz Trastoy, Francisco Corzana, Luis G.M. Basso, Montse Tersa, Carole L. Linster, Jacques Prandi, Floriane Gavotto, Todd L. Lowary, Sebastián Perrone, Alberto Marina, Marcelo E. Guerin, F.-Xabier Contreras

Publikováno v: Science Advances
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7 (42), ⟨10.1126/sciadv.abj4565⟩
Addi. Archivo Digital para la Docencia y la Investigación
instname
RIUR. Repositorio Institucional de la Universidad de La Rioja

Glycolipids are prominent components of bacterial membranes that play critical roles not only in maintaining the structural integrity of the cell but also in modulating host-pathogen interactions. PatA is an essential acyltransferase involved in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3720361a3bc619cbe003dbb5c82714d8
https://hal.archives-ouvertes.fr/hal-03420446

Super-Resolution Microscopy Using a Bioorthogonal-Based Cholesterol Probe Provides Unprecedented Capabilities for Imaging Nanoscale Lipid Heterogeneity in Living Cells

Autor: María Calleja-Felipe, Ornella Morana, Iratxe Rojo-Bartolomé, Aroa Arboleya, Marta Szynkiewicz, Alexia Martin, June Olazar-Intxausti, F.-Xabier Contreras, Jorge Bernardino de la Serna, Dalila Ciceri, Maier Lorizate, Jon Ander Nieto-Garai, Oihana Terrones

Publikováno v: Addi. Archivo Digital para la Docencia y la Investigación
instname

Despite more than 20 years of work since the lipid raft concept was proposed, the existence of these nanostructures remains highly controversial due to the lack of noninvasive methods to investigate their native nanorganization in living unperturbed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f70dcdd78194e587c5755a0dbee367e
http://hdl.handle.net/10810/53119

Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1.

Autor: Nuria Izquierdo-Useros, Maier Lorizate, F-Xabier Contreras, Maria T Rodriguez-Plata, Bärbel Glass, Itziar Erkizia, Julia G Prado, Josefina Casas, Gemma Fabriàs, Hans-Georg Kräusslich, Javier Martinez-Picado

Publikováno v: PLoS Biology, Vol 10, Iss 4, p e1001315 (2012)

HIV-1 is internalized into mature dendritic cells (mDCs) via an as yet undefined mechanism with subsequent transfer of stored, infectious virus to CD4+ T lymphocytes. Thus, HIV-1 subverts a DC antigen capture mechanism to promote viral spread. Here,

Externí odkaz: https://doaj.org/article/67a559c3a89b445685c0d1df2464c95f