Zobrazeno 1 - 10
of 63
pro vyhledávání: '"F. Woodward Hopf"'
Autor:
Raizel M. Frasier, Thatiane De Oliveira Sergio, Phillip A. Starski, Angela J. Grippo, F. Woodward Hopf
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionMental health conditions remain a substantial and costly challenge to society, especially in women since they have nearly twice the prevalence of anxiety disorders. However, critical mechanisms underlying sex differences remain incomplete
Externí odkaz:
https://doaj.org/article/b2a4441552504744addf643e49c058a7
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Neurons of the locus coeruleus (LC) are implicated in attention and arousal. Here the authors use CRISPR/Cas9 to disrupt dopamine beta hydroxylase in LC neurons and see this reduces LC-evoked sleep-to-wake transitions and wake length.
Externí odkaz:
https://doaj.org/article/26d3ded6f2ac42a3a93af43e8748351e
Autor:
Matthew B Pomrenze, E Zayra Millan, F. Woodward Hopf, Ronald eKeiflin, Rajani eMaiya, Angelo eBlasio, Jahan eDadgar, Viktor eKharazia, Giordano eDe Guglielmo, Elena eCrawford, Patricia H. Janak, Olivier eGeorge, Kenner C. Rice, Robert O. Messing
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates adaptive responses to stress. CRF projections from neurons in the central nucleus of the amygdala (CeA) to the brainstem are of particular interest for their role
Externí odkaz:
https://doaj.org/article/8a11322451a04110bf704ab01cc4fe68
Autor:
Phillip Starski, Mitch Morningstar, Simon Katner, Raizel Frasier, Thatiane De Oliveira Sergio, Sarah Wean, Christopher Lapish, F Woodward Hopf
Compulsive-like alcohol drinking (CLAD), where intake persists despite adverse consequences, is often a core facet of alcohol use disorder. Recent work sheds light on underlying mechanisms, but much remains unknown about CLAD etiology. Previously, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3466f6183c098086467451c9251639e
https://doi.org/10.1101/2022.05.24.493243
https://doi.org/10.1101/2022.05.24.493243
Autor:
Susmita Chatterjee, Nathan Santos, Joan Holgate, Carolina L Haass-Koffler, F Woodward Hopf, Viktor Kharazia, Henry Lester, Antonello Bonci, Selena E Bartlett
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68300 (2013)
Human genetic association studies have shown gene variants in the α5 subunit of the neuronal nicotinic receptor (nAChR) influence both ethanol and nicotine dependence. The α5 subunit is an accessory subunit that facilitates α4* nAChRs assembly in
Externí odkaz:
https://doaj.org/article/6f289e2fd0f94888a0c610893ebf2350
Autor:
F. Woodward Hopf
Publikováno v:
Biological Psychiatry. 87:940-941
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d20bdeefc97bf4781241cd417cb151b6
https://doi.org/10.1016/j.biopsych.2020.04.005
https://doi.org/10.1016/j.biopsych.2020.04.005
Autor:
Hitoshi Morikawa, F. Woodward Hopf, Kelly Lei, Matthew B. Pomrenze, Jorge Tovar-Diaz, Robert O. Messing, Angelo Blasio, Simone M. Giovanetti, Rajani Maiya
The central amygdala (CeA) is important for fear responses to discrete cues. Recent findings indicate that the CeA also contributes to states of sustained apprehension that characterize anxiety, although little is known about the neural circuitry inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efbab4259fd4dd26a3b28ae99822492
https://europepmc.org/articles/PMC6363927/
https://europepmc.org/articles/PMC6363927/
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Locus coeruleus (LC) neurons in the brainstem have long been associated with attention and arousal. Optogenetic stimulation of LC-NE neurons induces immediate sleep-to-wake transitions. However, LC neurons also secrete other neurotransmitters in addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ac4302ba76f6ab4d65944d83984566
https://doi.org/10.1038/s41467-018-07566-3
https://doi.org/10.1038/s41467-018-07566-3
Publikováno v:
Alcohol. 55:9-16
Addiction is mediated in large part by pathological motivation for rewarding, addictive substances, and alcohol-use disorders (AUDs) continue to extract a very high physical and economic toll on society. Compulsive alcohol drinking, where intake cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfc602d5b083b3a258d2cc66b9a5d13
https://doi.org/10.1016/j.alcohol.2016.07.008
https://doi.org/10.1016/j.alcohol.2016.07.008
Autor:
F. Woodward Hopf, Regina A. Mangieri
Publikováno v:
The Neuropharmacology of Alcohol ISBN: 9783319965222
Ionotropic glutamate receptors (AMPA, NMDA, and kainate receptors) play a central role in excitatory glutamatergic signaling throughout the brain. As a result, functional changes, especially long-lasting forms of plasticity, have the potential to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c1bc1358d5f6cf923501ec641a3e5d6
https://doi.org/10.1007/164_2018_105
https://doi.org/10.1007/164_2018_105