Zobrazeno 1 - 10
of 841
pro vyhledávání: '"F. Wong-Staal"'
Autor:
W. Xu, Y. Zhang, L.-Y. Yeh, C.R. Ruprecht, F. Wong-Staal, B.A. McFadden, T.R. Reddy, R.M. Ruprecht
Publikováno v:
BioTechniques, Vol 32, Iss 6, Pp 1266-1270 (2002)
A fast and efficient site-directed mutagenesis method has been developed, using the newly constructed plasmid pTPS19, which expresses the toxic CcdB protein originally encoded by the E. coli F plasmid. Once the target gene is cloned into pTPS19, desi
Externí odkaz:
https://doaj.org/article/f95b4163ce8a4a8ba00eb5e80fd2af31
Publikováno v:
Blood. 90:4822-4831
Evaluation of candidate genes for stem cell gene therapy for acquired immunodeficiency syndrome (AIDS) has been limited by the difficulty of supporting in vitro T-cell differentiation of genetically modified hematopoietic progenitor cells. Using a no
Publikováno v:
Blood. 90:4822-4831
Evaluation of candidate genes for stem cell gene therapy for acquired immunodeficiency syndrome (AIDS) has been limited by the difficulty of supporting in vitro T-cell differentiation of genetically modified hematopoietic progenitor cells. Using a no
Publikováno v:
Blood. 82:2774-2780
tat protein, a human immunodeficiency virus (HIV) gene product that functions as a transactivator for HIV replication, is known to be secreted extracellularly by infected cells. To determine the potential role of tat in the dissemination of HIV into
Publikováno v:
Blood. 82:2774-2780
tat protein, a human immunodeficiency virus (HIV) gene product that functions as a transactivator for HIV replication, is known to be secreted extracellularly by infected cells. To determine the potential role of tat in the dissemination of HIV into
Autor:
A. Hildebrand, William S. Craig, F. Wong-Staal, Michael D. Pierschbacher, Bruce E. Vogel, Shu-Jan Lee, Erkki Ruoslahti
Publikováno v:
The Journal of Cell Biology
Several studies have addressed the interaction of the HIV Tat protein with the cell surface. Our analysis of the cell attachment-promoting activity of Tat and peptides derived from it revealed that the basic domain of Tat, not the arg-gly-asp (RGD) s
Publikováno v:
Histology and histopathology. 22(2)
RNAi-mediated gene inactivation has become a cornerstone of the present day gene function studies that are the foundation of mechanism and target based drug discovery and development, which could potentially shorten the otherwise long process of drug
NR4A1, 2, 3--an orphan nuclear hormone receptor family involved in cell apoptosis and carcinogenesis
Publikováno v:
Histology and histopathology. 21(5)
Three members of the NR4A1/Nur77/ NGFIB orphan nuclear hormone receptor subfamily (NR4A1, NR4A2, and NR4A3) belong to the steroid nuclear hormone receptor superfamily. They share similar structural features and have no known natural ligand. They cons
Publikováno v:
Retrovirology. 2
Background Human xenograft tumor models are widely used for evaluation of potential cancer targets, by assessing the antitumor effects of specific agents, such as siRNA. siRNA is usually stably introduced into tumor cells prior to transplantation. Ho
Autor:
J R, Gilbert, F, Wong-Staal
Publikováno v:
Somatic cell and molecular genetics. 26(1-6)
Lentiviral vectors have received much attention in recent years due to their ability to efficiently transduce non-dividing cells. Of the lentiviruses HIV-2 and SIV offer several unique benefits as the basis for lentiviral vector design. HIV-1, HIV-2