Zobrazeno 1 - 10
of 478
pro vyhledávání: '"F. Willis"'
Autor:
M.K. Nyanzu, M. Abdalla, E. Fragkakis, B. Ajayi, J. Keefe, T. Bishop, J. Bernard, F. Willis, Y. Reya, E. Pereira, M. Papadopoulos, D. Lui
Publikováno v:
Brain and Spine, Vol 2, Iss , Pp 101250- (2022)
Externí odkaz:
https://doaj.org/article/fad049c0dcb347df918570c999a67995
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106614- (2024)
Perineuronal nets (PNNs) are extracellular matrix structures that surround excitable neurons and their proximal dendrites. PNNs play an important role in neuroprotection against oxidative stress. Oxidative stress within motor neurons can act as a tri
Externí odkaz:
https://doaj.org/article/9b188baf16d24c7cb9c3cb629ea735bb
Autor:
Samreen N. Shaikh, Emily F. Willis, Max Dierich, Yi Xu, Samuel J. S. Stuart, Glenda C. Gobe, Abate A. Bashaw, Oliver Rawashdeh, Seung Jae Kim, Jana Vukovic
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract Graft-versus-host disease (GVHD) is a serious complication of otherwise curative allogeneic haematopoietic stem cell transplants. Chronic GVHD induces pathological changes in peripheral organs as well as the brain and is a frequent cause of
Externí odkaz:
https://doaj.org/article/99d2dd503b23450b9fb4733adf954daa
Autor:
Sabine M. Ulamec, Roberto Maya-Martinez, Emily J. Byrd, Katherine M. Dewison, Yong Xu, Leon F. Willis, Frank Sobott, George R. Heath, Patricija van Oosten Hawle, Vladimir L. Buchman, Sheena E. Radford, David J. Brockwell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The authors of this work characterize the effect of amino acid substitution on α-synuclein (α-Syn) aggregation. Residues 38 and 42 (in addition to 39) within the P1 region of α-Syn affect amyloid formation. The effect of substitution at position 3
Externí odkaz:
https://doaj.org/article/795dea3b15b941688aa5f281361c1332
Autor:
Emily F. Willis, Ellen R. Gillespie, Kirsten Guse, Adrian W. Zuercher, Fabian Käsermann, Marc J. Ruitenberg, Jana Vukovic
Publikováno v:
Brain, Behavior, and Immunity. 109:37-50
Intravenous immunoglobulin (IVIG) is a promising immune-modulatory therapy for limiting harmful inflammation and associated secondary tissue loss in neurotrauma. Here, we show that IVIG therapy attenuates spatial learning and memory deficits followin
Autor:
Leon F. Willis, Amit Kumar, Tushar Jain, Isabelle Caffry, Yingda Xu, Sheena E. Radford, Nikil Kapur, Maximiliano Vásquez, David J. Brockwell
Publikováno v:
Engineering Reports, Vol 2, Iss 5, Pp n/a-n/a (2020)
Abstract The development of therapeutic monoclonal antibodies (mAbs) can be hindered by their tendency to aggregate throughout their lifetime, which can illicit immunogenic responses and render mAb manufacturing unfeasible. Consequently, there is a n
Externí odkaz:
https://doaj.org/article/0794a7674f0f47228bea193cef914dcc
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background Components of the innate immune complement system have been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS) specifically using hSOD1 transgenic animals; however, a comprehensive examination of complement expr
Externí odkaz:
https://doaj.org/article/44b8e714290847afa9c9c6c5b7c5ba39
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Akademický článek
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