Zobrazeno 1 - 10
of 1 631
pro vyhledávání: '"F. Wilkinson"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Conductive atomic force microscopy (c-AFM) can provide simultaneous maps of the topography and electrical current flow through materials with high spatial resolution and it is playing an increasingly important role in the characterization of
Externí odkaz:
https://doaj.org/article/1b9732436b52441aa4c25109a50470df
Publikováno v:
IEEE Access, Vol 12, Pp 72288-72302 (2024)
In this paper, we propose an innovative approach to multi-band source-segmentation that addresses the constraints of single-band max-tree-based methods and effectively manages component-graph complexity. Our method extends multiple max-trees by integ
Externí odkaz:
https://doaj.org/article/2ea4ad6f07504917955e936d3625672c
Autor:
Clare E. West, Mohd Karim, Maria J. Falaguera, Leo Speidel, Charlotte J. Green, Lisa Logie, Jeremy Schwartzentruber, David Ochoa, Janet M. Lord, Michael A. J. Ferguson, Chas Bountra, Graeme F. Wilkinson, Beverley Vaughan, Andrew R. Leach, Ian Dunham, Brian D. Marsden
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-13 (2023)
Abstract Advancing age is the greatest risk factor for developing multiple age-related diseases. Therapeutic approaches targeting the underlying pathways of ageing, rather than individual diseases, may be an effective way to treat and prevent age-rel
Externí odkaz:
https://doaj.org/article/bd0a4e946edc4e929857d3968138af9c
Autor:
Tri A. Sardjono, Peter M. A. Van Ooijen, I. Ketut Eddy Purnama, Berlian Al Kindhi, Ardian Yusuf Wicaksono, Eko M. Yuniarno, G. J. Verkerke, Mauridhi Hery Purnomo, Michael H. F. Wilkinson
Publikováno v:
IEEE Access, Vol 10, Pp 110323-110334 (2022)
Deformable models are widely used in medical image segmentation methods, to find not only single but also multiple objects within an image. They have the ability to follow the contours of an object of interest, define the boundary of ROI (Region Of I
Externí odkaz:
https://doaj.org/article/8043f96531bc4e59ae52aeac612cf193
Autor:
Denise M. Smith, Michael L. Niehoff, Karen Ling, Paymaan Jafar-Nejad, Frank Rigo, Susan A. Farr, Miles F. Wilkinson, Andrew D. Nguyen
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
A common cause of frontotemporal dementia (FTD) are nonsense mutations in the progranulin (GRN) gene. Because nonsense mutations activate the nonsense-mediated RNA decay (NMD) pathway, we sought to inhibit this RNA turnover pathway as a means to incr
Externí odkaz:
https://doaj.org/article/82651a85b9bf4f0082f04f8ac4b72d06
Autor:
Denise M Smith, Michael L Niehoff, Karen Ling, Paymaan Jafar-Nejad, Frank Rigo, Susan A Farr, Miles F Wilkinson, Andrew D Nguyen
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282822 (2023)
A common cause of frontotemporal dementia (FTD) are nonsense mutations in the progranulin (GRN) gene. Because nonsense mutations activate the nonsense-mediated RNA decay (NMD) pathway, we sought to inhibit this RNA turnover pathway as a means to incr
Externí odkaz:
https://doaj.org/article/2ad2dd39ffdc4781a13de2fb69a7b98a
Autor:
Charles F. Wilkinson
In Crossing the Next Meridian, Charles F. Wilkinson, an expert on federal public lands, Native American issues, and the West's arcane water laws explains some of the core problems facing the American West now and in the years to come. He examines the
Autor:
Milad Mortazavi, Yangsu Ren, Shubham Saini, Danny Antaki, Celine L. St. Pierre, April Williams, Abhishek Sohni, Miles F. Wilkinson, Melissa Gymrek, Jonathan Sebat, Abraham A. Palmer
Publikováno v:
Cell Genomics, Vol 2, Iss 3, Pp 100102- (2022)
Summary: Mouse substrains are an invaluable model for understanding disease. We compared C57BL/6J, which is the most commonly used inbred mouse strain, with eight C57BL/6 and five C57BL/10 closely related inbred substrains. Whole-genome sequencing an
Externí odkaz:
https://doaj.org/article/5054ab5d148241bd8a1a1f891627b975
Publikováno v:
The Neurodiagnostic Journal. :1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c82e8676ef8e551ddf98a5a8390f5c4a
https://doi.org/10.1080/21646821.2023.2178807
https://doi.org/10.1080/21646821.2023.2178807
Autor:
Kun Tan, Samantha H Jones, Blue B Lake, Jennifer N Chousal, Eleen Y Shum, Lingjuan Zhang, Song Chen, Abhishek Sohni, Shivam Pandya, Richard L Gallo, Kun Zhang, Heidi Cook-Andersen, Miles F Wilkinson
Publikováno v:
eLife, Vol 9 (2020)
The UPF3B-dependent branch of the nonsense-mediated RNA decay (NMD) pathway is critical for human cognition. Here, we examined the role of UPF3B in the olfactory system. Single-cell RNA-sequencing (scRNA-seq) analysis demonstrated considerable hetero
Externí odkaz:
https://doaj.org/article/8a0c1bf4ffd94ebebb77c22183768b09