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Bis-basic-substituted polycyclic aromatic compounds. New class of antiviral agents. 1. Bisalkamine esters of fluorenone-, fluorenol-, and fluorenedicarboxylic acids

Autor: Andrews Er, S. W. Horgan, A. D. Sill, F. W. Sweet, Roberts Em, William L. Albrecht, Robert W. Fleming

Publikováno v: Journal of Medicinal Chemistry. 16:240-245

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7eeab5da6c4a28f21b20cb7793ffa0
https://doi.org/10.1021/jm00261a016

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Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 5. Bis-basic ethers of anthraquinone and bisalkamine esters of anthraquinonedicarboxylic acids

Autor: Andrews Er, J. W. Hoffman, A. D. Sill, Mayer Gd, P. L. Tiernan, Grisar Jm, Robert W. Fleming, F. W. Sweet

Publikováno v: Journal of medicinal chemistry. 17(9)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fcf9eb2c838423dde32789754e0487f
https://pubmed.ncbi.nlm.nih.gov/4369818

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ChemInform Abstract: Bis-Basic-Substituted Polycyclic Aromatic Compounds. A New Class of Antiviral Agents. Part 7. Bisalkamine Esters of 9-Oxoxanthene-2,7-dicarboxylic Acid, 3,6-Bis-Basic Ethers of Xanthen-9-one, and 2,7-Bis(aminoacyl)xanthen-9-ones, -xan

Autor: J. M. Grisar, Robert W. Fleming, B. J. Scheve, J. F. Grunwell, A. A. Carr, G. D. Mayer, F. W. Sweet, A. D. Sill, D. R. Meyer

Publikováno v: Chemischer Informationsdienst. 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a1f03a84a6114db8a104c61bdd0ed50
https://doi.org/10.1002/chin.197701260

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ChemInform Abstract: BIS-BASIC-SUBSTITUTED POLYCYCLIC AROMATIC COMPOUNDS, A NEW CLASS OF ANTIVIRAL AGENTS PART 5, BIS-BASIC ETHERS OF ANTHRAQUINONE AND BISALKAMINE ESTERS OF ANTHRAQUINONEDICARBOXYLIC ACIDS

Autor: J. M. Grisar, A. D. Sill, Robert W. Fleming, G. D. Mayer, J. W. Hoffman, F. W. Sweet, Edwin Ruffin Andrews, P. L. Tiernan

Publikováno v: Chemischer Informationsdienst. 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34e35b7c82d1c4cab4990f6fa884085a
https://doi.org/10.1002/chin.197501231

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ChemInform Abstract: SYNTHESIS OF S-TRIAZOLOCYCLOALKYL-, S-TRIAZOLOBENZOCYCLOALKYL-, AND S-TRIAZOLOCYCLOALKYLHYDROTHIADIAZINES

Autor: W. L. ALBRECHT, W. D. JUN. JONES, F. W. SWEET

Publikováno v: Chemischer Informationsdienst. 9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a04a74bd6b215b5ce513c5488585588f
https://doi.org/10.1002/chin.197836224

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Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 7. Bisalkamine esters of 9-oxoxanthene-2,7-dicarboxylic acid, 3,6-bis-basic ethers of xanthen-9-one, and 2,7-bis(aminoacyl)xanthen-9-ones-xanthenes, and -thioxanthenes

Autor: F. W. Sweet, B. J. Scheve, A. A. Carr, Robert W. Fleming, J. F. Grunwell, Grisar Jm, A. D. Sill, D. R. Meyer, G D Mayer

Publikováno v: Journal of medicinal chemistry. 19(9)

3,6-Bis[2-(dimethylamino)ethoxy]-9H-xanthen-9-one dihydrochloride (4, RMI 10874DA) and 1,1'-(9H-xanthene 2,7-diyl)bis[2-(dimethylamino)ethanone] dihydrochloride (16, RMI 11513DA) were found to prolong survival of mice infected with lethal challenges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f197a662d1d2f50026b70a0ca30753
https://pubmed.ncbi.nlm.nih.gov/185385

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ChemInform Abstract: BIS-BASISCH SUBSTITUIERTE POLYCYCLISCHE AROMATEN, EINE NEUE KLASSE VON VERBINDUNGEN MIT WIRKUNG GEGEN VIREN 1. MITT. BIS-ALKAMIN-ESTER VON FLUORENON-, FLUORENOL- UND FLUOREN-DICARBONSAEUREN

Autor: Robert W. Fleming, E. Mc. C. Roberts, S. W. Horgan, F. W. Sweet, A. D. Sill, William L. Albrecht, Edwin Ruffin Andrews

Publikováno v: Chemischer Informationsdienst. 4

Aus den entsprechenden Saurechloriden erhalt man die Fluorenon-dicarbonsaureester-thigester (I) mit basischen Gruppen.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20dd8ddcb4556013c939e099a69f14d6
https://doi.org/10.1002/chin.197329268

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