Zobrazeno 1 - 10
of 97
pro vyhledávání: '"F. W. Saunders"'
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 4, p e1000071 (2008)
BIOLOGY IS ENCODED IN MOLECULAR SEQUENCES: deciphering this encoding remains a grand scientific challenge. Functional regions of DNA, RNA, and protein sequences often exhibit characteristic but subtle motifs; thus, computational discovery of motifs i
Externí odkaz:
https://doaj.org/article/c4bcaa1c08354951850c7ba274930266
Autor:
Anil S Thakur, Gautier Robin, Gregor Guncar, Neil F W Saunders, Janet Newman, Jennifer L Martin, Bostjan Kobe
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1091 (2007)
Crystallization is a major bottleneck in the process of macromolecular structure determination by X-ray crystallography. Successful crystallization requires the formation of nuclei and their subsequent growth to crystals of suitable size. Crystal gro
Externí odkaz:
https://doaj.org/article/0185573710f247c4a1ea407cf547006f
Autor:
Ingrid S. Tarr, Roger Pamphlett, Shu Yang, Emily P. McCann, Garth A. Nicholson, Jennifer A. Fifita, Dominic B. Rowe, Ian P. Blair, Alison L. Hogan, Denis C. Bauer, Neil F. W. Saunders, Katharine Y. Zhang, Jasmin Galper, Kelly L. Williams
Publikováno v:
Neurodegenerative Diseases. 17:304-312
Background: Mutations in the genes encoding the heterogeneous nuclear ribonucleoproteins hnRNPA1 and hnRNPA2/B1 have been reported in a multisystem proteinopathy that includes amyotrophic lateral sclerosis (ALS) and inclusion body myopathy associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494f5a97ca62df9531723711348b38ce
https://doi.org/10.1159/000481258
https://doi.org/10.1159/000481258
Autor:
Marie-France Hétu, A Lahaye, Murray F. Matangi, J.D. Spence, P Norman, Amer M. Johri, F W Saunders, Julia E. Herr, D.K. Heyland
Publikováno v:
European Heart Journal. 40
Background/Introduction L-carnitine (L-C) has been investigated as a potential therapy for cardiovascular (CV) disease, but its direct effects on human atherosclerosis are unknown. Epidemiological studies suggest a possible reduction of CV risk facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4fa10d93aa1bda5d80c3e53ca7a5cce
https://doi.org/10.1093/eurheartj/ehz745.0807
https://doi.org/10.1093/eurheartj/ehz745.0807
Autor:
Bostjan Kobe, Neil F. W. Saunders
Publikováno v:
Nucleic Acids Research
The Predikin webserver allows users to predict substrates of protein kinases. The Predikin system is built from three components: a database of protein kinase substrates that links phosphorylation sites with specific protein kinase sequences; a perl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2511210d035a0c56852e9f74bb73dced
http://europepmc.org/articles/PMC2447752
http://europepmc.org/articles/PMC2447752
Autor:
Friedrich Lottspeich, K Sohn, Dirk Rothenstein, Klaus Schröppel, M. Roehm, Harald Brunner, Neil F. W. Saunders, Constantin F. Urban, Steffen Rupp
Publikováno v:
Eukaryotic Cell. 4:2160-2169
We applied two-dimensional gel electrophoresis to identify downstream effectors of CPH1 and EFG1 under hypha-inducing conditions in Candida albicans . Among the proteins that were expressed in wild-type cells but were strongly downregulated in a cph1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156c5ae5aec745b8d33d9a02bf864a64
https://doi.org/10.1128/ec.4.12.2160-2169.2005
https://doi.org/10.1128/ec.4.12.2160-2169.2005
Autor:
Neil F. W. Saunders, Mark J. Raftery, Michael Guilhaus, Amber Goodchild, Ricardo Cavicchioli, Paul M. G. Curmi
Publikováno v:
Journal of Proteome Research. 4:464-472
Using liquid chromatography-mass spectrometry, 528 proteins were identified that are expressed during growth at 4 degrees C in the cold adapted archaeon, Methanococcoides burtonii. Of those, 135 were annotated previously as unique or conserved hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40c28d8de3330626296d2f2f601b5d8
https://doi.org/10.1021/pr049797+
https://doi.org/10.1021/pr049797+
Publikováno v:
Journal of Proteome Research. 4:473-480
Using isotope coded affinity tag (ICAT) chromatography and liquid chromatography-mass spectrometry, 163 proteins were identified from the cold-adapted archaeon, Methanococcoides burtonii. 14 proteins were differentially expressed during growth at 4 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c3a634610a739b284b06916326afb7
https://doi.org/10.1021/pr049760p
https://doi.org/10.1021/pr049760p
Publikováno v:
Journal of Proteome Research. 3:1164-1176
Genome sequence data of the cold-adapted archaeon, Methanococcoides burtonii, was linked to liquid chromatography-mass spectrometry analysis of the expressed-proteome to define the key biological processes functioning at 4 degrees C. 528 proteins ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbe4a60127c303cff2a9f00d4a7dd9e
https://doi.org/10.1021/pr0498988
https://doi.org/10.1021/pr0498988
Autor:
Michael Guilhaus, Amber Goodchild, Neil F. W. Saunders, Ricardo Cavicchioli, Mark J. Raftery, Haluk Ertan, Paul M. G. Curmi
Publikováno v:
Molecular Microbiology. 53:309-321
A global view of the biology of the cold-adapted archaeon Methanococcoides burtonii was achieved using proteomics. Proteins specific to growth at 4degreesC versus T-opt (23degreesC) were identified by mass spectrometry using the draft genome sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::030e48ef939bd70dd378d65c156c3d14
https://doi.org/10.1111/j.1365-2958.2004.04130.x
https://doi.org/10.1111/j.1365-2958.2004.04130.x