Zobrazeno 1 - 10
of 220
pro vyhledávání: '"F. W. James"'
Publikováno v:
American Journal of Epidemiology
In this study, we examined temporal changes in the incidence of primary biliary cirrhosis (PBC) and investigated associations between PBC incidence and sociodemographic factors and spatial clustering. We included 982 patients aged ≥40 years from No
Autor:
Carmen Martin-Ruiz, Wendy P. J. den Elzen, Laura Wiley, Oliver F. W. James, Andrew Kingston, Thomas B. L. Kirkwood, Bernard Keavney, Martin P Eccles, Louise Robinson, Simon H. S. Pearce, Catharien M. U. Hilkens, Joanna Collerton, Mick Dunn, Carol Jagger, Duncan Talbot, John C. Mathers, John Bond, Karen Davies, Michael Catt, Thomas von Zglinicki
Publikováno v:
Mechanisms of Ageing and Development, 132(10), 496-502
Sensitive and specific biomarkers of ageing are needed to evaluate interventions to extend health span. However, there is growing evidence that information provided by candidate biomarkers may change with age itself. Little is yet known about the val
Autor:
Anna Baragiotta, Simon H. S. Pearce, Peter T. Donaldson, Valerie Wilson, Julia L. Newton, Oliver F. W. James, Margaret F. Bassendine, C. Venturi, Sivakumar Veeramani, Annarosa Floreani, David Jones, John J. Taylor
Publikováno v:
Clinical Gastroenterology and Hepatology. 5:755-760
Twin and family studies suggest that there is a significant heritable component to primary biliary cirrhosis (PBC). Selected cytotoxic T-lymphocyte-associated antigen-4 (CTLA4) gene polymorphisms have been proposed as nonspecific determinants of dise
Autor:
Niall E. F. Cartlidge, John Bamford, Anthony Hildreth, Christopher S. Gray, Peter Sandercock, Donna E Johnston, Oliver F. W. James, Janice E. O’Connell, K. George M. M. Alberti
Publikováno v:
The Lancet Neurology. 6:397-406
Summary Background Hyperglycaemia after acute stroke is a common finding that has been associated with an increased risk of death. We sought to determine whether treatment with glucose-potassium-insulin (GKI) infusions to maintain euglycaemia immedia
Autor:
C. Venturi, David Jones, Michael A. Heneghan, Oliver F. W. James, J Underhill, Anna Baragiotta, Annarosa Floreani, Margaret F. Bassendine, Peter T. Donaldson
Publikováno v:
Hepatology. 44:667-674
Twin and family studies suggest there is a significant genetic component to primary biliary cirrhosis (PBC). However, the inability to replicate reported associations has been a recurring problem, with the only consistently reported genetic associati
Publikováno v:
Liver International. 24:194-197
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease, which predominantly affects women. It is characterised histologically by necroinflammation of small intrahepatic bile ducts and biochemically by elevated serum alkaline phosphata
Publikováno v:
Gut. 53:865-870
Background: Many patients with primary biliary cirrhosis (PBC) are asymptomatic at the time of diagnosis. However, because most studies of asymptomatic PBC have been small and from tertiary centres, asymptomatic PBC remains poorly characterised. Aims
Autor:
Martin I Prince, Oliver F. W. James
Publikováno v:
Clinics in Liver Disease. 7:795-819
Over the last 30 years, many studies have reported on the epidemiology of PBC. Substantial increases in prevalence were noted in the majority of studies examining longitudinal data, and several have reported increases in the incidence of PBC. Further
Publikováno v:
Stroke. 34:1604-1609
Background and Purpose— There are no previously published studies of the long-term outcome of stroke in sub-Saharan Africa. Our goal was to determine the case fatality, time to and cause of death, and recovery in a hospital cohort of stroke patient