Zobrazeno 1 - 10 of 203 pro vyhledávání: '"F. W. Fitch"'
1
TCR-gamma delta cells in CD3 zeta-deficient mice contain Fc epsilon RI gamma in the receptor complex but are specifically unresponsive to antigen
Autor: R Khattri, A I Sperling, D Qian, F W Fitch, E W Shores, P E Love, J A Bluestone
Publikováno v: The Journal of Immunology. 157:2320-2327
Unlike TCR-alpha beta cells, TCR-gamma delta cells express a distinct member of the zeta family, the gamma-chain of Fc epsilon RI (Fc epsilon RI gamma) within the TCR complex. To study the role of the Fc epsilon RI gamma-chain in TCR-gamma delta cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25e5ab9f1c6570f36f0261840a58ded6
https://doi.org/10.4049/jimmunol.157.6.2320
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2
Differential requirement for protein tyrosine kinase Fyn in the functional activation of antigen-specific T lymphocyte clones through the TCR or Thy-1
Autor: D W Lancki, D Qian, P Fields, T Gajewski, F W Fitch
Publikováno v: The Journal of Immunology. 154:4363-4370
The protein tyrosine kinase Fyn has been shown to be involved in signal transduction through the TCR and the glycosyl-phosphatidylinositol-linked surface molecule Thy-1 expressed on T cells. In this study, we examine the requirement for Fyn expressio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a48c741385ec4780e0d987cb984c7971
https://doi.org/10.4049/jimmunol.154.9.4363
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3
IL-4-producing CD8+ T cell clones can provide B cell help
Autor: D C Cronin, R Stack, F W Fitch
Publikováno v: The Journal of Immunology. 154:3118-3127
Interactions between CD4+ T cells and B cells are mediated by both soluble factors and cell surface molecules. The Ag-independent interaction between the CD40 ligand, expressed on activated T cells, and its CD40 receptor, expressed on B cells, enhanc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b554925ce9ea138440d91082502ff030
https://doi.org/10.4049/jimmunol.154.7.3118
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4
IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2
Autor: R M Stack, D J Lenschow, G S Gray, J A Bluestone, F W Fitch
Publikováno v: The Journal of Immunology. 152:5723-5733
IL-4 has been shown to be involved in the early stages of B cell maturation. Changes induced by IL-4 include cell enlargement, increased viability, and increased MHC class II expression. However IL-4 alone does not induce B cell activation as defined
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85f5ca45c39d2ecc4f89ddb73f84dad7
https://doi.org/10.4049/jimmunol.152.12.5723
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5
Cytolytic activity of murine IL-2-producing CD4+ and CD8+ T cell clones cycles in response to IL-2
Autor: M D McKisic, D W Lancki, D C Cronin, F W Fitch
Publikováno v: The Journal of Immunology. 151:4055-4066
Alloreactive or OVA-reactive cloned murine CD4+ or CD8+ T cells that produce IL-2 exhibit greatly reduced cytolytic activity after being cultured with high concentrations of rIL-2. Furthermore, such cells fail to produce lymphokines or proliferate wh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4deccd8adb791c85ed2d9ea3e11bdefa
https://doi.org/10.4049/jimmunol.151.8.4055
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7
Cytolytic activity of murine CD4+ T cell clones correlates with IFN-gamma production in mouse strains having a BALB/c background
Autor: M D McKisic, D W Lancki, F W Fitch
Publikováno v: The Journal of Immunology. 150:3793-3805
CD4+ murine T cell clones were derived from various strains of mice, and their pattern of lymphokine secretion and cytolytic activity was compared. Limiting dilution cultures were established with lymph node cells from mice sensitized with OVA. Allor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ae880e40b4d21b1b8189799a55b0c5d
https://doi.org/10.4049/jimmunol.150.9.3793
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8
Identification and propagation of a putative immunosuppressive orphan parvovirus in cloned T cells
Autor: M D McKisic, D W Lancki, G Otto, P Padrid, S Snook, D C Cronin, P D Lohmar, T Wong, F W Fitch
Publikováno v: The Journal of Immunology. 150:419-428
A putative parvovirus related to minute virus of mice (MVM), but distinct from MVM-prototype and MVM-immunosuppressive, was identified, using serologic techniques and Southern blot analysis, in maintenance cultures of established T cell clones. This
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7b3d6d18c4a495aa38a635afd3fa15f
https://doi.org/10.4049/jimmunol.150.2.419
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9
A murine CD4-, CD8- T cell receptor-gamma delta T lymphocyte clone specific for herpes simplex virus glycoprotein I
Autor: R M Johnson, D W Lancki, A I Sperling, R F Dick, P G Spear, F W Fitch, J A Bluestone
Publikováno v: The Journal of Immunology. 148:983-988
The role of TCR-gamma delta T lymphocytes in immune responses is currently not well understood. TCR-gamma delta cells have a limited repertoire suggesting that TCR-gamma delta T a limited number of evolutionarily conserved Ag such as nonpolymorphic M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edfa7e9da4b3a01addab1d2134b1fe98
https://doi.org/10.4049/jimmunol.148.4.983
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10
Some cloned murine CD4+ T cells recognize H-2Ld class I MHC determinants directly. Other cloned CD4+ T cells recognize H-2Ld class I MHC determinants in the context of class II MHC molecules
Autor: M D McKisic, A J Sant, F W Fitch
Publikováno v: The Journal of Immunology. 147:2868-2874
Murine T lymphocytes recognize nominal Ag presented by class I or class II MHC molecules. Most CD8+ T cells recognize Ag presented in the context of class I molecules, whereas most CD4+ cells recognize Ag associated with class II molecules. However,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59f70acc747d0f4f5a42828bca89ce77
https://doi.org/10.4049/jimmunol.147.9.2868
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