Výsledky vyhledávání - "F. W. Miller"

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes

Publikováno v: Genes & Immunity. 16:470-480

Autoimmune muscle diseases (myositis) comprise a group of complex phenotypes influenced by genetic and environmental factors. To identify genetic risk factors in patients of European ancestry, we conducted a genome-wide association study (GWAS) of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bcd9c6902e2b96ed557a87be46c59d
https://doi.org/10.1038/gene.2015.28

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Predominant TCR-alpha beta variable and joining gene expression by muscle-infiltrating lymphocytes in the idiopathic inflammatory myopathies

Autor: T P O'Hanlon, M C Dalakas, P H Plotz, F W Miller

Publikováno v: The Journal of Immunology. 152:2569-2576

The idiopathic inflammatory myopathies (IIM) are a heterogeneous group of diseases in which autoreactive T cells are thought to play a pathogenetic role. We have determined the pattern of TCR-alpha beta gene expression by muscle-infiltrating lymphocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38818bdd5a7b676ff749c3dbe6ddc2cf
https://doi.org/10.4049/jimmunol.152.5.2569

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Validation of the Childhood Health Assessment Questionnaire in the juvenile idiopathic myopathies. Juvenile Dermatomyositis Disease Activity Collaborative Study Group

Autor: A M, Huber, J E, Hicks, P A, Lachenbruch, M D, Perez, L S, Zemel, R M, Rennebohm, C A, Wallace, C B, Lindsley, M H, Passo, S H, Ballinger, S L, Bowyer, A M, Reed, P H, White, I M, Katona, F W, Miller, L G, Rider, B M, Feldman

Publikováno v: The Journal of rheumatology. 28(5)

To examine the validity of the Childhood Health Assessment Questionnaire (CHAQ) in patients with juvenile idiopathic inflammatory myopathy (IIM).One hundred fifteen patients were enrolled in a multicenter collaborative study, during which subjects we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eb3ce02d7eb3f65a424f26789841958a
https://pubmed.ncbi.nlm.nih.gov/11361197

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Magnetic resonance imaging detection of occult skin and subcutaneous abnormalities in juvenile dermatomyositis. Implications for diagnosis and therapy

Autor: A B, Kimball, R M, Summers, M, Turner, E M, Dugan, J, Hicks, F W, Miller, L G, Rider

Publikováno v: Arthritis and rheumatism. 43(8)

To assess the utility of magnetic resonance imaging (MRI) of skin, subcutaneous tissue, and fascia in evaluating disease activity in juvenile dermatomyositis (DM).Short tau inversion recovery (STIR) MRI of the proximal thighs and buttocks, cutaneous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::50e69e73671f9326c5e015c0a6baf8ac
https://pubmed.ncbi.nlm.nih.gov/10943878

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Genetic risk and protective factors for idiopathic inflammatory myopathy in Koreans and American whites: a tale of two loci

Autor: L G, Rider, E, Shamim, S, Okada, J P, Pandey, I N, Targoff, T P, O'Hanlon, H A, Kim, Y S, Lim, H, Han, Y W, Song, F W, Miller

Publikováno v: Arthritis and rheumatism. 42(6)

To better understand genetic contributions to autoimmunity, immunogenetic markers were studied in two racially discrete and geographically isolated populations of patients with idiopathic inflammatory myopathy (IIM).Clinical characteristics, as well

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c28f6e77d2f8b692c4142f569d288787
https://pubmed.ncbi.nlm.nih.gov/10366124

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Clinical, serologic, and immunogenetic features of familial idiopathic inflammatory myopathy

Autor: L G, Rider, R C, Gurley, J P, Pandey, I, Garcia de la Torre, A E, Kalovidouris, T P, O'Hanlon, L A, Love, R C, Hennekam, L L, Baumbach, H E, Neville, C A, Garcia, J, Klingman, M, Gibbs, M H, Weisman, I N, Targoff, F W, Miller

Publikováno v: Arthritis and rheumatism. 41(4)

To describe the clinical, serologic, and immunogenetic features of familial idiopathic inflammatory myopathy (IIM) and to compare these with the features of sporadic IIM.Clinical signs and symptoms, autoantibodies, HLA-DRB1 and DQA1 alleles, and GM/K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2ca359b4f03825de614f83bceccbb3d
https://pubmed.ncbi.nlm.nih.gov/9550481

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Familial autoimmunity in pedigrees of idiopathic inflammatory myopathy patients suggests common genetic risk factors for many autoimmune diseases

Autor: L R, Ginn, J P, Lin, P H, Plotz, S J, Bale, R L, Wilder, A, Mbauya, F W, Miller

Publikováno v: Arthritis and rheumatism. 41(3)

To test the hypothesis that many autoimmune diseases share common genetic risk factors and to define the frequency and distribution of autoimmune diseases in relatives of patients with very rare disorders, the idiopathic inflammatory myopathies (IIM)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae26a8ea4b2eb2c0ca7fb57022ec50c2
https://pubmed.ncbi.nlm.nih.gov/9506566

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Treatment of refractory myositis: a randomized crossover study of two new cytotoxic regimens

Autor: L, Villalba, J E, Hicks, E M, Adams, J B, Sherman, M F, Gourley, R L, Leff, B C, Thornton, S H, Burgess, P H, Plotz, F W, Miller

Publikováno v: Arthritis and rheumatism. 41(3)

To assess the clinical usefulness of 2 novel therapies for treatment-resistant myositis.Thirty patients with refractory myositis, of whom 25 had an inadequate or no response to previous cytotoxic therapy, were randomized to begin either a combination

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4902b19654b8d46bb3dc23e3d16b630e
https://pubmed.ncbi.nlm.nih.gov/9506565

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Development of validated disease activity and damage indices for the juvenile idiopathic inflammatory myopathies: I. Physician, parent, and patient global assessments. Juvenile Dermatomyositis Disease Activity Collaborative Study Group

Autor: L G, Rider, B M, Feldman, M D, Perez, R M, Rennebohm, C B, Lindsley, L S, Zemel, C A, Wallace, S H, Ballinger, S L, Bowyer, A M, Reed, M H, Passo, I M, Katona, F W, Miller, P A, Lachenbruch

Publikováno v: Arthritis and rheumatism. 40(11)

To determine the reliability, content validity, and responsiveness of physician global assessments of disease activity and damage in the juvenile idiopathic inflammatory myopathies (IIM), and to investigate concordance among physician, parent, and pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::517a010e92df20762bae21983503e8f5
https://pubmed.ncbi.nlm.nih.gov/9365086

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