Zobrazeno 1 - 10 of 244 pro vyhledávání: '"F. Van Eeden"'
1
Akademický článek
Thalassemia, a human blood disorder
Autor: F. Shafique, S. Ali, T. Almansouri, F. Van Eeden, N. Shafi, M. Khalid, S. Khawaja, S. Andleeb, M. ul Hassan
Publikováno v: Brazilian Journal of Biology, Vol 83 (2021)
Abstract A group of inherited blood defects is known as Thalassemia is among the world’s most prevalent hemoglobinopathies. Thalassemias are of two types such as Alpha and Beta Thalassemia. The cause of these defects is gene mutations leading to lo
Externí odkaz: https://doaj.org/article/e97603ce667f420e974baa3f8d85fce2
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2
Akademický článek
Systemic and Airway Epigenetic Disruptions Are Associated with Health Status in COPD
Autor: Ana I. Hernandez Cordero, Xuan Li, Chen Xi Yang, Julia Yang, Julia L. MacIsaac, Kristy Dever, Michael S. Kobor, Stephen Milne, Stephan F. van Eeden, Tawimas Shaipanich, Stephen Lam, Janice M. Leung, Don D. Sin
Publikováno v: Biomedicines, Vol 11, Iss 1, p 134 (2023)
Epigenetic modifications are common in chronic obstructive pulmonary disease (COPD); however, their clinical relevance is largely unknown. We hypothesized that epigenetic disruptions are associated with symptoms and health status in COPD. We profiled
Externí odkaz: https://doaj.org/article/463c23cd21d74f45b6e16347812f1dfe
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3
Akademický článek
Airway Eosinophilia on Bronchoalveolar Lavage and the Risk of Exacerbations in COPD
Autor: Chunman Germain Ho, Stephen Milne, Xuan Li, Chen Xi Yang, Fernando Sergio Leitao Filho, Chung Yan Cheung, Julia Shun Wei Yang, Ana I Hernández Cordero, Cheng Wei Tony Yang, Tawimas Shaipanich, Stephan F van Eeden, Janice M Leung, Stephen Lam, Don D Sin
Publikováno v: Biomedicines, Vol 10, Iss 6, p 1412 (2022)
The associations between airway eosinophilia, measured in sputum or peripheral blood, and acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are inconsistent. We therefore aimed to determine the association between eosinophilia in
Externí odkaz: https://doaj.org/article/0088314fb8474ed5a63a92359b68577f
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4
Akademický článek
Inhaled Corticosteroids Selectively Alter the Microbiome and Host Transcriptome in the Small Airways of Patients with Chronic Obstructive Pulmonary Disease
Autor: William Yip, Xuan Li, Graeme J. Koelwyn, Stephen Milne, Fernando Sergio Leitao Filho, Chen Xi Yang, Ana I. Hernández Cordero, Julia Yang, Cheng Wei Tony Yang, Tawimas Shaipanich, Stephan F. van Eeden, Janice M. Leung, Stephen Lam, Kelly M. McNagny, Don D. Sin
Publikováno v: Biomedicines, Vol 10, Iss 5, p 1110 (2022)
Background: Patients with chronic obstructive pulmonary disease (COPD) are commonly treated with inhaled corticosteroid/long-acting ß2-agonist combination therapy. While previous studies have investigated the host–microbiome interactions in COPD,
Externí odkaz: https://doaj.org/article/017237e0b7f04cc5b05b75260a171d9a
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5
Akademický článek
Adhesion molecule gene variants and plasma protein levels in patients with suspected obstructive sleep apnea.
Autor: Andrew J Sandford, Amanda Ha, David A Ngan, Loubna Akhabir, Aabida Saferali, Nurit Fox, A J Hirsch Allen, Simon C Warby, Stephan F van Eeden, Najib T Ayas
Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210732 (2019)
Study objectivesUntreated obstructive sleep apnea (OSA) patients have an increased risk of cardiovascular disease (CVD). Adhesion molecules, including soluble E-selectin (sE-selectin), intercellular adhesion molecule-1 (ICAM-1), and vascular adhesion
Externí odkaz: https://doaj.org/article/4d7d6cc9d00940ad86790deff39a693a
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8
Lung Macrophages: Pivotal Immune Effector Cells Orchestrating Acute and Chronic Lung Diseases
Autor: Stephan F. van Eeden, Don D. Sin
Publikováno v: Macrophages-Celebrating 140 Years of Discovery
Macrophages-Celebrating 140 Years of Discovery ISBN: 9781803556246
Macrophages are key immune cells, where they play a pivotal role in host defense and tissue homeostasis. The lungs have two major subsets, alveolar macrophages (AMs) found in airspaces and interstitial macrophages (IMs) found in lung tissues. Lung ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf062cee138b7f24393a8748c0c59c60
https://mts.intechopen.com/articles/show/title/lung-macrophages-pivotal-immune-effector-cells-orchestrating-acute-and-chronic-lung-diseases
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9
Obstructive Sleep Apnea Severity, Body Mass Index, and Circulating Levels of Cellular Adhesion Molecules
Autor: Nurit Fox, Ismail Laher, Bernardo U Peres, A J Hirsch Allen, Najib T. Ayas, Andrew J. Sandford, Fernanda R. Almeida, Tetyana Kendzerska, Rachel Jen, Stephan F. van Eeden, Aditi Shah
Publikováno v: Lung. 198:939-945
To investigate the relationship between obstructive sleep apnea (OSA) severity, body mass index (BMI), and circulating levels of inflammatory adhesion molecules (intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-selectin). A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f54a94143a8249c239bba62be00f7cc
https://doi.org/10.1007/s00408-020-00401-x
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10
Immunmodulation bei chronisch-obstruktiver Lungenerkrankung: Aktuelle Konzepte und zukünftige Strategien
Autor: J C Hogg, Stephan F. van Eeden
Publikováno v: Kompass Pneumologie. 8:6-20
Die chronisch-obstruktive Lungenerkrankung (chronic obstructive pulmonary disease, COPD) wird durch das langjährige aktive oder passive Einatmen schädlicher Partikel und Gase (vor allem, aber nicht nur, Zigarettenrauch) verursacht, wodurch es zu ei
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9b6b2134d5e1036eb5243f4fa465d4d
https://doi.org/10.1159/000504951
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