Zobrazeno 1 - 10
of 1 290
pro vyhledávání: '"F. VOGT"'
Publikováno v:
European Journal of Medical Research, Vol 24, Iss 1, Pp 1-5 (2019)
Abstract Background Intensive care unit (ICU) capacity is a scant and precious resource in hospitals. Therefore, an optimal occupancy rate as well as detailed occupation planning is of great importance. Most literature deals with admission to the ICU
Externí odkaz:
https://doaj.org/article/f5976b53d50944708acde5cb179f2a8e
Autor:
Maura Galimberti, Maria R. Nucera, Vittoria D. Bocchi, Paola Conforti, Elena Vezzoli, Matteo Cereda, Camilla Maffezzini, Raffaele Iennaco, Andrea Scolz, Andrea Falqui, Chiara Cordiglieri, Martina Cremona, Ira Espuny-Camacho, Andrea Faedo, Dan P. Felsenfeld, Thomas F. Vogt, Valeria Ranzani, Chiara Zuccato, Dario Besusso, Elena Cattaneo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Huntington’s disease (HD) causes selective degeneration of striatal and cortical neurons, resulting in cell mosaicism of coexisting still functional and dysfunctional cells. The impact of non-cell autonomous mechanisms between these cellul
Externí odkaz:
https://doaj.org/article/f886204e00154c1a8e03cf3cdc9d56ff
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Colorectal cancer (CRC) is a complex and heterogeneous disease characterized by dysregulated interactions between tumor cells and the immune system. The tumor microenvironment plays a pivotal role in cancer initiation as well as progression, with mye
Externí odkaz:
https://doaj.org/article/ed205b08bf2948a390fdb58d49b731e2
Autor:
Eva-Maria Cox, Mohamed El-Behi, Stefanie Ries, Johannes F. Vogt, Vivien Kohlhaas, Thomas Michna, Benoît Manfroi, Mona Al-Maarri, Florian Wanke, Boaz Tirosh, Corinne Pondarre, Harry Lezeau, Nir Yogev, Romy Mittenzwei, Marc Descatoire, Sandra Weller, Jean-Claude Weill, Claude-Agnès Reynaud, Pierre Boudinot, Luc Jouneau, Stefan Tenzer, Ute Distler, Anne Rensing-Ehl, Christoph König, Julian Staniek, Marta Rizzi, Aude Magérus, Frederic Rieux-Laucat, F. Thomas Wunderlich, Nadine Hövelmeyer, Simon Fillatreau
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112378- (2023)
Summary: The signals controlling marginal zone (MZ) and follicular (FO) B cell development remain incompletely understood. Here, we show that AKT orchestrates MZ B cell formation in mice and humans. Genetic models that increase AKT signaling in B cel
Externí odkaz:
https://doaj.org/article/92cc14fd0e5540159395986a3869f5d7
DNA methylation study of Huntington’s disease and motor progression in patients and in animal models
Autor:
Ake T. Lu, Pritika Narayan, Matthew J. Grant, Peter Langfelder, Nan Wang, Seung Kwak, Hilary Wilkinson, Richard Z. Chen, Jian Chen, C. Simon Bawden, Skye R. Rudiger, Marc Ciosi, Afroditi Chatzi, Alastair Maxwell, Timothy A. Hore, Jeff Aaronson, Jim Rosinski, Alicia Preiss, Thomas F. Vogt, Giovanni Coppola, Darren Monckton, Russell G. Snell, X. William Yang, Steve Horvath
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Although Huntington’s disease (HD) is a well-studied genetic disorder, less is known about the epigenetic changes underlying it. Here, the authors characterize DNA methylation levels in tissues from patients, a mouse huntingtin (Htt) gene knock-in
Externí odkaz:
https://doaj.org/article/9415f3c0bb6441ffad6d13aeb09b8ee8
Autor:
Paul Dantonio, Norma P. Tavakoli, Brooke Migliore, Elizabeth McCown, Timothy Lim, Sunju Park, Michele Caggana, Katerina S. Kucera, Han Phan, Natalie Street, Konstantinos Petritis, Robert F. Vogt
Publikováno v:
International Journal of Neonatal Screening, Vol 9, Iss 1, p 13 (2023)
Pilot studies to detect newborns with Duchenne Muscular Dystrophy (DMD) by newborn bloodspot screening (NBS) have been conducted under the New York State Newborn Screening Program (NYS) and are currently in progress as part of the Early Check Program
Externí odkaz:
https://doaj.org/article/50059432012c4dfe8f39ab3fe2862908
Autor:
B. Bonfond, Z. H. Yao, G. R. Gladstone, D. Grodent, J.‐C. Gérard, J. Matar, B. Palmaerts, T. K. Greathouse, V. Hue, M. H. Versteeg, J. A. Kammer, R. S. Giles, C. Tao, M. F. Vogt, A. Mura, A. Adriani, B. H. Mauk, W. S. Kurth, S. J. Bolton
Publikováno v:
AGU Advances, Vol 2, Iss 1, Pp n/a-n/a (2021)
Abstract Dawn storms are among the brightest events in the Jovian aurorae. Up to now, they had only been observed from Earth‐based observatories, only showing the Sun‐facing side of the planet. Here, we show for the first time global views of the
Externí odkaz:
https://doaj.org/article/9c6034768a7446e6bf5afb93ec339397
Autor:
Lucile Megret, Barbara Gris, Satish Sasidharan Nair, Jasmin Cevost, Mary Wertz, Jeff Aaronson, Jim Rosinski, Thomas F Vogt, Hilary Wilkinson, Myriam Heiman, Christian Neri
Publikováno v:
eLife, Vol 10 (2021)
Loss of cellular homeostasis has been implicated in the etiology of several neurodegenerative diseases (NDs). However, the molecular mechanisms that underlie this loss remain poorly understood on a systems level in each case. Here, using a novel comp
Externí odkaz:
https://doaj.org/article/6b1d0cbc21bb45b297ea7b0f27e6a897
Publikováno v:
International Journal of Neonatal Screening, Vol 8, Iss 2, p 37 (2022)
Dr [...]
Externí odkaz:
https://doaj.org/article/5d9b89fcc1824551a32938ab68ef6df5
Autor:
Natsuko Macabuag, William Esmieu, Perla Breccia, Rebecca Jarvis, Wesley Blackaby, Ovadia Lazari, Liudvikas Urbonas, Maria Eznarriaga, Rachel Williams, Annelieke Strijbosch, Rhea Van de Bospoort, Kim Matthews, Cole Clissold, Tammy Ladduwahetty, Huw Vater, Patrick Heaphy, Douglas G. Stafford, Hong-Jun Wang, John E. Mangette, George McAllister, Vahri Beaumont, Thomas F. Vogt, Hilary A. Wilkinson, Elizabeth M. Doherty, Celia Dominguez
Publikováno v:
Journal of medicinal chemistry. 65(18)
Huntington's disease (HD) is a lethal autosomal dominant neurodegenerative disorder resulting from a CAG repeat expansion in the huntingtin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9b7293f23145d9276a05495bc08822
https://pubmed.ncbi.nlm.nih.gov/36098485
https://pubmed.ncbi.nlm.nih.gov/36098485