Opposite Effects of Mechanical Action of Fluid Flow on Proangiogenic Factor Secretion From Human Adipose-Derived Stem Cells With and Without Oxidative Stress

Autor: B. BRAVO, C. DE DURANGO, A. GONZALEZ, A. GORTAZAR, X. SANTOS, J. FORTEZA-VILA, F. VIDAL-VANACLOCHA

Publikováno v: JOURNAL OF CELLULAR PHYSIOLOGY
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
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Mechanical forces, hypoxia, and oxidative stress contribute to skin renewal, perfusion, and wound healing, but how are they regulating subcutaneous adipose-derived stem cells (ASCs) in the inflammatory microenvironment associated to skin repair and d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::3f0860b43c5a5b03abda33a347e64a6e
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=1515

Theophylline administration markedly reduces hepatic and pulmonary implantation of B16-F10 melanoma cells in mice

Autor: Simone Beninati, Alessandro Lentini, Michele Caraglia, F. Vidal-Vanaclocha, Alberto Abbruzzese, Francesco Facchiano

Publikováno v: Melanoma Research. 10:435-443

Theophylline-treated B16-F10 melanoma cells show a lower experimental metastatic potential in vivo. To identify the possible mechanism(s) involved and on the basis of previous reports, we tested the induction of apoptosis in B16-F10 cells. Fluorescen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99d2c8e2fa6942de69341d4bfcb0f01
https://doi.org/10.1097/00008390-200010000-00005

Growth-associated changes in glutathione content correlate with liver metastatic activity of B16 melanoma cells

Autor: J, Carretero, E, Obrador, M J, Anasagasti, J J, Martin, F, Vidal-Vanaclocha, J M, Estrela

Publikováno v: Clinicalexperimental metastasis. 17(7)

B16 melanoma (B16M) was used to study the relationship between glutathione (GSH) metabolism and the metastatic activity of malignant cells. GSH content increased in B16M cells during the initial period of exponential growth in vitro, to reach a maxim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9596f831832a822f79f15ade5d8663da
https://pubmed.ncbi.nlm.nih.gov/10845555

Characterization of a new human liver myofibroblast cell line: transcriptional regulation of plasminogen activator inhibitor type I by transforming growth factor beta 1

Autor: F X, Weill, S, Blazejewski, J F, Blanc, S, Huet, J M, Gauthier, V, Neaud, E, Olaso, L, Dubuisson, V, Azais-Braesco, F, Vidal-Vanaclocha, C, Balabaud, P, Bioulac-Sage, J, Rosenbaum

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 77(1)

Myofibroblasts (MF) are a major effector cell type in liver fibrogenesis, where they are thought to derive from the activation of hepatic stellate cells. Cultured human MF, grown from liver explants, retain most of the in vivo characteristics of live

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd6d01bb4fc257ce6c26851faa8f033a
https://pubmed.ncbi.nlm.nih.gov/9251679

Interleukin-1 receptor blockade reduces the number and size of murine B16 melanoma hepatic metastases

Autor: F, Vidal-Vanaclocha, C, Amézaga, A, Asumendi, G, Kaplanski, C A, Dinarello

Publikováno v: Cancer research. 54(10)

Hepatic metastasis in melanoma is affected by processes of tumor cell adhesion to sinusoidal cells, avoidance of cytotoxic cells, and local growth-promoting activity. A role for interleukin-1 (IL-1) in these events was evaluated in vitro and in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::224536643e277ea4a4bdb56bcb9f3a9c
https://pubmed.ncbi.nlm.nih.gov/8168095