Zobrazeno 1 - 10
of 28
pro vyhledávání: '"F. T. Counter"'
Autor:
J. M. Greene, David A. Preston, Lawrence C. Creemer, F. T. Counter, Jonathan W. Paschal, R L Clemens, J G Amos, William E. Alborn, K A Sullivan, Herbert A. Kirst
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:1436-1441
Dirithromycin is the 9-N,11-O-oxazine adduct formed from 9(S)-erythromycylamine and 2-(2-methoxyethoxy)acetaldehyde in which the methoxyethoxymethyl substituent on the oxazine ring possesses the R configuration. Epidirithromycin is its isomer in whic
Publikováno v:
The Journal of Antibiotics. 47:1052-1064
The synthesis and microbiological evaluation of a new series of 3-thiazol-4-yl-carba-1-dethiacephalosporins is described. Structure activity relationship was achieved by changing substitution at the 2-position of the thiazole moiety. The result was a
Autor:
Jeffrey S. Kasher, Andrew Pike, Susan E. Draheim, Judy A. Eudaly, F. T. Counter, Robert J. Ternansky
Publikováno v:
Journal of Medicinal Chemistry. 36:3224-3229
The structure-activity relationship among a series of novel pyrazolidinone antibacterial agents is described. Specifically, the effect of modification of the side chain attached to the nitrogen at C-7 was explored in an attempt to improve the potency
Publikováno v:
Journal of Industrial Microbiology. 11:253-257
The colonizing potential of Escherichia coli K12 containing a vector coding for somidobove (bovine somatotropin) was determined. Treated male and female Fischer-344 rats were given a single oral gavage inoculum of sucrose with/without tetracycline (1
Autor:
Robert Theodore Vasileff, Brown Raymond Frank, J. F. Quay, F. T. Counter, J. A. Webber, E. O. Davidson, Terry D. Lindstrom, Jeffrey S. Kasher, William Henry Walker Lunn, Mitchell I. Steinberg, J. M. Jun. Morin, J. A. Eudaly, Paul W. Ensminger, R. E. Koehler, Allen S. Katner, Michael Dean Kinnick, John K. Swartzendruber, Jan R. Turner, David A. Preston, J. K. Shadle, Walter E. Wright, J. F. Stucky, K. D. Kurz, John L. Ott, Karen M. Zimmerman
Publikováno v:
ChemInform. 22
Publikováno v:
ChemInform. 26
The synthesis and microbiological evaluation of a new series of 3-thiazol-4-yl-carba-1-dethiacephalosporins is described. Structure activity relationship was achieved by changing substitution at the 2-position of the thiazole moiety. The result was a
Autor:
F. T. Counter, Boeck Laverne Dwaine, Frederick P. Mertz, Patrick J. Baker, Yao Raymond Che-Fong, William E. Alborn, Walter Mitsuo Nakatsukasa, D. S. Fukuda, J. N. Hobbs, Norris E. Allen, Jon S. Mynderse, Donnis M. Berry, James A. Mabe, P. W. Ensminger, John L. Ott
Publikováno v:
The Journal of Antibiotics. 43:623-633
New semi-naphthaquinone antibiotics A80915A, B, C, and D were isolated from the fermented broth of Streptomyces aculeolatus A80915 (NRRL 18422). Factors A and C, present in both the broth filtrate and mycelial methanol extract, and factors B and D, f
Autor:
P. W. Ensminger, John L. Ott, David A. Preston, F. T. Counter, D. S. Fukuda, J. N. Hobbs, C. Y. E. Wu, Jon S. Mynderse, Norris E. Allen
Publikováno v:
The Journal of Antibiotics. 43:616-622
A54145 complex is made up of eight factors; A, A1, B, B1, C, D, E, and F which were active in vitro (MIC 0.25 approximately greater than 32 micrograms/ml) against Gram-positive aerobic organisms. The complex, factor B and B1 were found to be active a
Publikováno v:
The Journal of antibiotics. 47(9)
The synthesis and microbiological evaluation of a new series of 3-thiazol-4-yl-carba-1-dethiacephalosporins is described. Structure activity relationship was achieved by changing substitution at the 2-position of the thiazole moiety. The result was a
Autor:
Jonathan W. Paschal, David A. Preston, J. M. Greene, Herbert A. Kirst, P. W. Ensminger, F. T. Counter, C. Y. E. Wu, A. M. Felty-Duckworth
Publikováno v:
Antimicrobial agents and chemotherapy. 35(6)
Dirithromycin is a 9-N-11-O-oxazine derivative which is formed by condensation of 9(S)-erythromycylamine with 2-(2-methoxyethoxy)acetaldehyde. Dirithromycin is hydrolyzed, either under acidic conditions or in vivo, to its major active metabolite, 9(S