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of 37
pro vyhledávání: '"F. Stephen Laroux"'
Autor:
F. Stephen Laroux, Bradford L. McRae, Wallace Craig, Jamie Erickson, Stephanie M. Gaudette, Christopher Stedman, Christine M. Nelson, Gricelda H. Simler, Samuel D. Karsen, Annette J. Schwartz Sterman, Rajesh V. Kamath, Liang Zhang, Marc Wurbel, Soumya Mitra, Calvin S. Pohl, Ruoqi Peng
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Intestinal permeability and neutrophil activity are closely linked to inflammatory bowel disease (IBD) pathophysiology. Here we discuss two techniques for assessing permeability and neutrophil activity in mouse IBD models using near infrared (NIR) de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2f8a755a7d915f7ebbc5505f5af7c0
http://link.springer.com/article/10.1038/s41598-020-61756-y
http://link.springer.com/article/10.1038/s41598-020-61756-y
Akademický článek
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Autor:
Duncan Howie, Christopher Fraser, Lucia E. Rosas, Abhay R. Satoskar, F. Stephen Laroux, Massimo Morra, Anthony J. Coyle, Cox Terhorst, Svend Rietdijk, Aimée Julien, William A. Faubion
Ly108, a glycoprotein of the signaling lymphocytic activation molecule family of cell surface receptors expressed by T, B, NK, and APCs has been shown to have a role in NK cell cytotoxicity and T cell cytokine responses. In this study, we describe th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0c1d0ed6d720e7a098857124949156
https://doi.org/10.4049/jimmunol.174.10.5931
https://doi.org/10.4049/jimmunol.174.10.5931
Autor:
Adam S. Cockrell, Matthew B. Grisham, Shigeyuki Kawachi, Lan Feng, Laura Gray, Robert A. Specian, D. Neil Granger, Elaine M. Conner, Michael Wolcott, Stephen R. Jennings, Zenichi Morise, F. Stephen Laroux, Henri C. van der Heyde, Robert Chervenak
Publikováno v:
Inflammatory Bowel Diseases. 6:171-180
The objectives of this study were to quantify colonic cytokine and endothelial cell adhesion molecule (ECAM) expression in the colons of severe combined immunodeficient (SCID) mice reconstituted with different subsets of CD4+ T lymphocytes. We found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c958a568c834301eae56f88d74387883
https://doi.org/10.1002/ibd.3780060304
https://doi.org/10.1002/ibd.3780060304
Autor:
F. Stephen Laroux, Laura Gray, Dmitry V. Ostanin, Christopher G. Kevil, Kevin P. Pavlick, Kathryn L. Furr, Carla M. Brown, Matthew B. Grisham
Publikováno v:
International Immunology. 18:389-398
The b2 integrin lymphocyte function-associated antigen-1 (LFA-1; CD11a/CD18) is important for lymphocyte trafficking and activation as well as recruitment to sites of tissue inflammation. The objective of this study was to assess the role of ‘T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb4298d08cdcb8e29217670e9f4232c
https://doi.org/10.1093/intimm/dxh378
https://doi.org/10.1093/intimm/dxh378
Publikováno v:
The Journal of Immunology. 175:5596-5600
MyD88 is an adaptor protein for the TLR family of proteins that has been implicated as a critical mediator of innate immune responses to pathogen detection. In this study, we report that MyD88 plays a crucial role in killing Gram-negative bacteria by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4335dcf623801640b9f0be48b30ccf90
https://doi.org/10.4049/jimmunol.175.9.5596
https://doi.org/10.4049/jimmunol.175.9.5596
Autor:
William A. Faubion, Cristina Cozzo, Cox Terhorst, Ana C. Abadía-Molina, F. Stephen Laroux, Hongbin Ji, Gongxian Liao, Andrew J. Caton
Publikováno v:
The Journal of Immunology. 172:5823-5827
CD4+25+ regulatory T (Treg) cells maintain immunological self-tolerance through mechanisms that are only in part understood. Previous studies suggest that the glucocorticoid-induced TNFR-related protein (GITR), which is preferentially expressed on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631514b52606c9c01958d43bbb4d3873
https://doi.org/10.4049/jimmunol.172.10.5823
https://doi.org/10.4049/jimmunol.172.10.5823
Autor:
F. Stephen Laroux, Jason M. Hoffman, Kevin P. Pavlick, Laura Gray, Robert E. Wolf, Matthew B. Grisham, John W. Fuseler
Publikováno v:
Free Radical Biology and Medicine. 33:311-322
The inflammatory bowel diseases (IBD; Crohn's disease, ulcerative colitis) are a collection of chronic idiopathic inflammatory disorders of the intestine and/or colon. Although the pathophysiology of IBD is not known with certainty, a growing body of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b04feac72b31fe8065368dd56492859
https://doi.org/10.1016/s0891-5849(02)00853-5
https://doi.org/10.1016/s0891-5849(02)00853-5
Autor:
Guido Schürmann, F. Stephen Laroux, Wolfgang H. Cerwinka, Christian F. Krieglstein, Matthew B. Grisham, T. Matthias Brüwer, D. Neil Granger
Publikováno v:
Journal of Surgical Research. 101:166-175
There is growing clinical evidence suggesting that certain secondary lymphoid tissues (e.g., appendix and spleen) contribute to the initiation and/or perpetuation of ulcerative colitis. In this study, the importance of secondary lymphoid tissues in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f48157ebda96d0f1d27c4cc7143e493
https://doi.org/10.1006/jsre.2001.6223
https://doi.org/10.1006/jsre.2001.6223
Publikováno v:
Physiology. 16:272-277
The mucosal interstitia of the intestine and colon are continuously exposed to large amounts of dietary and microbial antigens. Fortunately, the mucosal immune system has evolved efficient mechanisms to distinguish potentially pathogenic from nonpath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289279727f6311b07bcb3f6883770d0b
https://doi.org/10.1152/physiologyonline.2001.16.6.272
https://doi.org/10.1152/physiologyonline.2001.16.6.272