Direct Observation of an Iron-Bound Terminal Hydride in [FeFe]-Hydrogenase by Nuclear Resonance Vibrational Spectroscopy

Autor: Judith F. Siebel, Ryan Gilbert-Wilson, Leland B. Gee, Agnieszka Adamska-Venkatesh, Thomas B. Rauchfuss, Edward J. Reijerse, Kenji Tamasaku, Cindy C. Pham, Vladimir Pelmenschikov, Stephen P. Cramer, Wolfgang Lubitz, Yoshitaka Yoda

Publikováno v: Journal of the American Chemical Society. 139:4306-4309

[FeFe]-hydrogenases catalyze the reversible reduction of protons to molecular hydrogen with extremely high efficiency. The active site (“H-cluster”) consists of a [4Fe–4S]H cluster linked through a bridging cysteine to a [2Fe]H subsite coordina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3d5577a5cb032657dd5fda38bed1b5
https://doi.org/10.1021/jacs.7b00686

A very-low-cost dosimeter based on the off-the-shelf CD4007 MOSFET array for in vivo radiotherapy applications

Autor: Márcio Cherem Schneider, O. F. Siebel, R.S. Souza, J. G. Pereira, F. J. Ramirez-Fernandez, Carlos Galup-Montoro

Publikováno v: Radiation Measurements. 75:53-63

Purpose This paper presents a low-cost MOSFET dosimeter suitable for in vivo radiotherapy applications. We analyze different methods to extract the threshold voltage and how this extraction is affected by the dose dependence of slope factor and carri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d7ca447746b0ea7a9de1aff35904f8e
https://doi.org/10.1016/j.radmeas.2015.03.004

Artificially maturated [FeFe] hydrogenase from Chlamydomonas reinhardtii: a HYSCORE and ENDOR study of a non-natural H-cluster

Autor: Trevor R. Simmons, Judith F. Siebel, Agnieszka Adamska-Venkatesh, Vincent Artero, Marc Fontecave, Edward J. Reijerse, Wolfgang Lubitz

Publikováno v: Physical Chemistry Chemical Physics
Physical Chemistry Chemical Physics, Royal Society of Chemistry, 2015, 17 (7), pp.5421-5430. ⟨10.1039/C4CP05426A⟩
Physical Chemistry Chemical Physics, 2015, 17 (7), pp.5421-5430. ⟨10.1039/C4CP05426A⟩

Hydrogenases are enzymes that catalyze the oxidation of H2 as well as the reduction of protons to form H2. The active site of [FeFe] hydrogenase is referred to as the "H-cluster" and consists of a "classical" [4Fe-4S] cluster connected via a bridging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0cb18ccafb4a5a2f21c25d216c56fb
https://doi.org/10.1039/c4cp05426a

A low-cost microcontrolled dosimeter based on CD4007 devices for in vivo radiotherapy applications

Autor: O. F. Siebel, C. W. C. Saraiva, Carlos Galup-Montoro, Márcio Cherem Schneider, F. J. Ramirez-Fernandez

Publikováno v: LASCAS

This work presents a low-cost microcontrolled dosimeter based on CD4007 device, a popular off-the-shelf CMOS circuit. This dosimeter is aimed at in vivo radiotherapy applications and combines a simple and accurate readout with a small size, low-cost,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56bd79df983c927de5a06be3b710b2ef
https://doi.org/10.1109/lascas.2016.7451061

Insertion of Heme b into the Structure of the Cys34-Carbamidomethylated Human Lipocalin α1-Microglobulin: Formation of a [(Heme)2(α1-Microglobulin)]3 Complex

Autor: Markus Knipp, Bo Åkerström, Judith F. Siebel, Robyn Laura Kosinsky

Publikováno v: ChemBioChem. 13:879-887

α(1)-Microglobulin (α(1)m) is a 26 kDa plasma and tissue protein belonging to the lipocalin protein family. Previous investigations indicate that the protein interacts with heme and suggest that it has a function in heme metabolism. However, detail

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8c28b60b2468377dd8ef26c35eba5e
https://doi.org/10.1002/cbic.201100808