Zobrazeno 1 - 10
of 481
pro vyhledávání: '"F. SCHELLER"'
Autor:
David Wolf, Renée Hartig, Yi Zhuo, Max F. Scheller, Mirko Articus, Marcel Moor, Valery Grinevich, Christiane Linster, Eleonora Russo, Wolfgang Weber-Fahr, Jonathan R. Reinwald, Wolfgang Kelsch
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Social recognition is essential for the formation of social structures. Many times, recognition comes with lesser exploration of familiar animals. This lesser exploration has led to the assumption that recognition may be a habituation memory
Externí odkaz:
https://doaj.org/article/a3b1546b7b9d4f5c96c915a242ef42c0
Autor:
Xueqi Cao, Sandra Huber, Ata Jadid Ahari, Franziska R. Traube, Marc Seifert, Christopher C. Oakes, Polina Secheyko, Sergey Vilov, Ines F. Scheller, Nils Wagner, Vicente A. Yépez, Piers Blombery, Torsten Haferlach, Matthias Heinig, Leonhard Wachutka, Stephan Hutter, Julien Gagneur
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background Rare oncogenic driver events, particularly affecting the expression or splicing of driver genes, are suspected to substantially contribute to the large heterogeneity of hematologic malignancies. However, their identification remai
Externí odkaz:
https://doaj.org/article/755f5087257242b19bf86f64f3d3d40e
Autor:
Christian Mertes, Ines F. Scheller, Vicente A. Yépez, Muhammed H. Çelik, Yingjiqiong Liang, Laura S. Kremer, Mirjana Gusic, Holger Prokisch, Julien Gagneur
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Aberrant splicing is a major contributor to rare disease, but detection accuracy using current methods is limited. Here, the authors develop an algorithm that detects aberrant splicing and intron retention events from RNA-seq data and apply it to dia
Externí odkaz:
https://doaj.org/article/d817b03e44e24e348c43693c66ebb662
Autor:
Christian Mertes, Ines F. Scheller, Vicente A. Yépez, Muhammed H. Çelik, Yingjiqiong Liang, Laura S. Kremer, Mirjana Gusic, Holger Prokisch, Julien Gagneur
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/d57dd2d4307f4866a1062b0569b6e510
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Detection of aberrantly spliced genes is an important step in RNA-seq-based rare disease diagnostics. We recently developed FRASER, a denoising autoencoder-based method for aberrant splicing detection that outperformed alternative approaches. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2686e3117c1216c96d7cf6535570821
https://doi.org/10.1101/2023.03.31.23287997
https://doi.org/10.1101/2023.03.31.23287997
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Christian Staufner, Slama A, Agnieszka Nadel, von Kleist-Retzow J, Mayr H, Thomas Meitinger, Ines F. Scheller, Loipfinger S, Peter Freisinger, Christina Ludwig, Kei Murayama, Smirnov D, Bucher M, Felix Distelmaier, Nasca A, Chen Meng, René Santer, Kulterer L, Sarah L. Stenton, Yepez, Jürgen Behr, Akira Ohtake, Maja Hempel, T. M. Strom, Metodi D. Metodiev, Saskia B. Wortmann, Christian Mertes, Mirjana Gusic, Holger Prokisch, Baski R, Dorota Piekutowska-Abramczuk, Verloo P, Riccardo Berutti, Rikke Katrine Jentoft Olsen, Robert Kopajtich, Daniele Ghezzi, Costanza Lamperti, Detlev Schindler, Julien Gagneur, Yasushi Okazaki, Roetig A
By lack of functional evidence, genome-based diagnostic rates cap at approximately 50% across diverse Mendelian diseases. Here, we demonstrate the effectiveness of combining genomics, transcriptomics, and, for the first time, proteomics and phenotypi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebb00b9f36f99cf158fd26b59438d08d
https://doi.org/10.1101/2021.03.09.21253187
https://doi.org/10.1101/2021.03.09.21253187
Autor:
Holger Prokisch, Michaela F. Müller, Vicente A. Yépez, Laure Fresard, Patricia F. Goldberg, Mirjana Gusic, Ines F. Scheller, Christian Mertes, Julien Gagneur, Daniela Klaproth-Andrade, Leonhard Wachutka
Publikováno v:
Nat. Protoc. 16, 1276–1296 (2021)
RNA sequencing (RNA-seq) has emerged as a powerful approach to discover disease-causing gene regulatory defects in individuals affected by genetically undiagnosed rare disorders. Pioneering studies have shown that RNA-seq could increase the diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2dd1dd015329f3f298234a31ce66fd
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61091
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61091