Zobrazeno 1 - 10
of 26
pro vyhledávání: '"F. S. Tjoeng"'
Autor:
Suzanne Metz, Mahima Trivedi, William M. Moore, Timothy J. Hagen, Mark E. Zupec, Jane R. Connor, Mark G. Currie, B. S. Pitzele, Kam F. Fok, M. V. Toth, Pamela T. Manning, Ronald Keith Webber, D. W. Hansen, Gina M. Jerome, F. S. Tjoeng
Publikováno v:
Journal of Medicinal Chemistry. 41:96-101
A series of analogues of 2-iminopiperidine have been prepared and shown to be potent inhibitors of the human nitric oxide synthase (NOS) isoforms. Methyl substitutions on the 4-position (3) or 4- and 6-positions (8) afforded the most potent analogues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0f40a0d108843036268d55d4ebec4b
https://doi.org/10.1021/jm9705059
https://doi.org/10.1021/jm9705059
Autor:
J A, Zablocki, J G, Rico, R B, Garland, T E, Rogers, K, Williams, L A, Schretzman, S A, Rao, P R, Bovy, F S, Tjoeng, R J, Lindmark
Publikováno v:
Journal of medicinal chemistry. 38(13)
Our initial orally active fibrinogen receptor antagonist benzamidinopentanoyl (BAP) series which was discovered through truncation of our i.v. antiplatelet agent (SC-52012) demonstrated modest oral activity in canine studies (ethyl [5-(4-amindinophen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f8b6ef5701f22716b8436aba26c226
https://pubmed.ncbi.nlm.nih.gov/7608903
https://pubmed.ncbi.nlm.nih.gov/7608903
Autor:
P. R. Bovy, F. S. Tjoeng, J. G. Rico, T. E. Rogers, R. J. Lindmark, J. A. Zablocki, R. B. Garland, D. E. McMackins, H. Dayringer, M. V. Tóth, M. E. Zupec, S. Rao, S. G. Panzer-Knodle, N. S. Nicholson, A. Salyers, B. B. Taite, M. F. Hérin, M. Miyano, L. P. Feigen, S. P. Adams
Publikováno v:
Peptides 1994 ISBN: 9789072199218
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::620b95f8fea5dddf6249efa11071a7a5
https://doi.org/10.1007/978-94-011-1468-4_25
https://doi.org/10.1007/978-94-011-1468-4_25
Autor:
S. G. Panzer-Knodle, Anita K. Salyers, Jeffery Alan Zablocki, Nancy S. Nicholson, Mihaly V. Toth, F. S. Tjoeng, Beatrice B. Taite, Larry P. Feigen
Publikováno v:
Peptides 1994 ISBN: 9789072199218
Peptides 1994
Peptides 1994
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efc4a84a1d002cddfb2f1537c91fdccf
https://doi.org/10.1007/978-94-011-1468-4_327
https://doi.org/10.1007/978-94-011-1468-4_327
Autor:
Mark G. Currie, Thomas P. Misko, Gina M. Jerome, F. S. Tjoeng, Ronald Keith Webber, William M. Moore
Publikováno v:
Journal of medicinal chemistry. 37(23)
L-N6-(1-Iminoethyl)lysine (L-NIL) has been synthesized and is shown to be both a potent and selective inhibitor of mouse inducible nitric oxide synthase (miNOS). L-NIL has an IC50 of 3.3 microM for miNOS compared to an IC50 of 92 microM for rat brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d220d88b43fe00fd47bcfa217f4cd6d3
https://pubmed.ncbi.nlm.nih.gov/7525961
https://pubmed.ncbi.nlm.nih.gov/7525961
Autor:
D. E. Mcmackins, Nancy S. Nicholson, Jeffery Alan Zablocki, Thomas E. Rogers, Mihaly V. Toth, Steven Paul Adams, Beatrice B. Taite, Anita K. Salyers, M. Miyano, M. E. Zupec, R. B. Garland, R. J. Lindmark, F. S. Tjoeng, Larry P. Feigen, P. R. Bovy, J. G. Rico, S G Panzer-Knodle
Publikováno v:
Peptides ISBN: 9789401042956
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad2aa1184fb4053127c0246eabcc23b
https://doi.org/10.1007/978-94-011-0683-2_101
https://doi.org/10.1007/978-94-011-0683-2_101
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(3)
8-Guanidino-octanoyl-aspartic acid-phenylalanine (SC-49992), a mimetic of the tetrapeptide arginine-glycine-aspartic acid-phenylalanine, is a potent inhibitor of platelet aggregation. In this study, the authors examined the effects of SC-49992 on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::438efb2d09ecc2fc0ff0d018e12555bf
https://pubmed.ncbi.nlm.nih.gov/8263779
https://pubmed.ncbi.nlm.nih.gov/8263779
Autor:
N S, Nicholson, S G, Panzer-Knodle, A K, Salyers, B B, Taite, L W, King, M, Miyano, R J, Gorczynski, M H, Williams, M E, Zupec, F S, Tjoeng
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 256(3)
Arginine-glycine-aspartic acid (RGD) is the minimal sequence in fibrinogen that leads to recognition and binding to the glycoprotein IIb/IIIa platelet receptor during aggregation. Analogs of tetrapeptides containing the RGD sequence have been previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::686b4c0562c62c615086ca03b307c66f
https://pubmed.ncbi.nlm.nih.gov/2005585
https://pubmed.ncbi.nlm.nih.gov/2005585
Autor:
F. S. TJOENG, G. A. HEAVNER
Publikováno v:
Chemischer Informationsdienst. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dbca35a7246954f099d87c9e335f9da
https://doi.org/10.1002/chin.198211340
https://doi.org/10.1002/chin.198211340
Publikováno v:
Chemischer Informationsdienst. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd8b14ad56d59b47785d91162109b430
https://doi.org/10.1002/chin.197912367
https://doi.org/10.1002/chin.197912367